Clinicopathological profile of adenoid cystic carcinoma of minor salivary gland tumour: our experience at a tertiary care centre

<p class="abstract"><strong>Background:</strong> Adenoid cystic carcinoma (ACC) is a rare malignant tumour originating from minor salivary glands. It is known for perineural spread, local recurrences and distant metastasis. The minor salivary gland tumour represents 3% of all head and neck neoplasms, whereas ACC constitutes about 0.5% of all malignant salivary gland neoplasms. This study was done to evaluate the clinical presentation and histopathological findings of minor salivary gland tumour.</p><p class="abstract"><strong>Methods:</strong> This study was done in the department of ENT, Bangalore Medical College and Research Institute from May 2017 to July 2019. Of the 25 patients with minor salivary gland tumour, 10 patients with ACC were considered for the present study. A detailed clinical and histopathological evaluation was done. Results were documented and tabulated in excel sheet. </p><p class="abstract"><strong>Results:</strong> We analysed data of 25 (16 female, 9 male) patients in the age group of 30-60 years, of which 10 patients had adenoid cystic carcinoma of minor salivary gland tumour. The most frequent site of tumour occurrence was noted in the hard palate (6 patients), followed by retromolar trigone (2 patients), floor of mouth (1 patient) and tongue (1 patient). The histopathological pattern noted most commonly in our study: cribriform pattern (6 cases), tubular (1 case) and solid (3 cases).</p><p class="abstract"><strong>Conclusions:</strong> ACC of minor salivary glands is rare. The otorhinolaryngologist should bear this clinical entity in mind when encountered with a painless swelling over the hard palate. This would lead to an early diagnosis and prompt management in such patients.</p>

Usual pathology at an unusual site - pleomorphic adenoma of parapharyngeal space: a rare case report

<p class="abstract">The parapharyngeal space is an inverted triangular pyramid. Parapharyngeal space masses account for 0.5% of all head and neck tumours and the majority is benign. Minor salivary gland tumour is a rare entity. A 75 years old female presented with a mass left side soft palate, per operatively mass of size about 6×3 cm was deeply extending to left parapharyngeal space and excised through transoral approach which came out to be pleomorphic adenoma of minor salivary gland on histopathological examination. Although external approach should be preferred due to important structure in vicinity but transoral approach can be used in selective cases.</p>

Myoepithelioma of nasal septum: a rare minor salivary gland tumour

Myoepithelioma is rare benign neoplasm, usually involves salivary glands and very less often seen in minor salivary glands of nose. Clinically it resembles like other tumour masses and thus posed challenge to clinician and pathologist. It becomes very difficult to diagnose due to its varied presentation and propensity for malignant transformation. We reported a case of a male patient with pink fleshy mass in the left nose with epistaxis and nasal obstruction. Preliminary biopsy and contrast-enhanced CT were done to delineate tumour size and type and then patient underwent endoscopic en-bloc resection. Histopathology and immunohistochemistry were found to be consistent for myoepithelioma. No recurrence was seen during a 6-month follow-up period. Its rarity should be a part of differential diagnosis among nasal tumours. Many of the tumour recurrences are associated with incomplete surgical resection so wide local excision with regular follow-up is essential for this rare entity.

Rare Occurrence of Lip Spindle Cell Lipoma

Spindle cell lipoma (SCL) is a rare distinct variant of lipoma, which presents as a painless, circumscribed, slow-growing, superficial lesion on the lip and can mimic a minor salivary gland tumour. We present a slow growing lower lip lesion and its management.Case Report. A 38-year-old female gave an eight-year history of a slow-growing mass on her lower lip with intermittent change in size. She presented with a submucosal nodule and thin overlying mucosa adjacent to the vermilion border. Surgical excision was carried as the diagnostic and therapeutic approach.Conclusion. Lip SCL is rare, and surgical excision is advocated in order to exclude underlying pathology and minor salivary gland tumours.

A minor salivary gland tumour presenting with dysphagia

A case is reviewed of a giant benign myoepithelioma of the soft palate presenting in an elderly female patient. Due to the large size of the lesion and its mass effect the patient developed dysphagia with subsequent significant weight loss. The clinico-pathological features of this rare tumour are described and the literature reviewed.

Glycogen-rich clear cell carcinoma in the tongue

The case of a minor salivary gland tumour, arising from the tongue, with nodal metastasis is presented. Biopsy of the tumour and fine-needle aspiration cytology of the neck swelling showed the presence of a clear cell carcinoma with evidence of nodal metastases. A commando operation was performed and the defect was reconstructed using a local tongue flap. The literature review indicated that the neoplasm was rare and its site of occurrence rather unusual.

Clinicopathological study of minor salivary gland tumour

Objectives: To find out the clinicopathological factors of minor salivary gland tumour. Methods: An attempt has been made to explore the relative incidence, clinical presentation, age and sex distribution, histological type, site of involvement of each cases of minor salivary gland tumour. Thirty cases of minor salivary gland tumours were studied. Sampling method was purposive, convenient. Data were collected in a prescribed data sheet from BSMMU, DMCH and BKZMC and SSH, Dhaka, during the period of October 2006 to May 2007. Results: In this series of 30 patients, 20 cases (67%) were found malignant and 10 cases (33%) were benign. Regarding the site of distribution of minor salivary gland tumour, 67% (20) were found in the hard palate, three patients were found in the soft palate, three patients in the check, two in the nasopharynx and two in the alveolar margin. All benign tumours in this series were pleomorphic adenoma. Monomorphic adenoma was not found in any patients. Among malignant tumour adenoid cystic carcinoma was the most common 70% (14). Pleomorphic adenoma was found in 33% (10) of total cases. Muco-epidermoid carcinoma was the 2nd most common malignant tumour 12.5% (4). Carcinoma in pleomorphic adenoma was the least common histological type 6% (2). Conclusion: Early diagnosis and treatment of minor salivary gland tumour is likely to lead to a fair outcome. All patients with swelling in hard palate should be considered as a minor salivary tumour. Sub clinical lymphatic metastasis may occur in malignant cases, so all patients should be referred for radiotherapy following surgery. Distant metastases are also rare in such type of malignancy. Key words: Minor salivary gland; Neoplasm. DOI: 10.3329/bjo.v17i1.7628 Bangladesh J Otorhinolaryngol 2011; 17(1): 48-52