scholarly journals Susceptibility of Haemophilus influenzae to Ampicillin as Determined by Use of a Modified, One-Minute Beta-Lactamase Test

1976 ◽  
Vol 9 (1) ◽  
pp. 196-198 ◽  
Author(s):  
J. Escamilla
Keyword(s):  
Haemophilus Influenzae ◽  
Beta Lactamase

scholarly journals Ketolide Treatment of Haemophilus influenzae Experimental Pneumonia

1999 ◽  
Vol 43 (3) ◽  
pp. 708-710 ◽  
Author(s):  
Kerryl E. Piper ◽  
Mark S. Rouse ◽  
James M. Steckelberg ◽  
Walter R. Wilson ◽  
Robin Patel
Keyword(s):  
Haemophilus Influenzae ◽  
Murine Model ◽  
Beta Lactamase ◽  
Experimental Pneumonia ◽  
Pulmonary Clearance ◽  
Erythromycin A

The MICs of HMR 3004 and HMR 3647 at which 90% of beta-lactamase-producing Haemophilus influenzae isolates were inhibited were 4 and 2 μg/ml, respectively. Both HMR 3004 and HMR 3647 were active against beta-lactamase-producing H. influenzae in a murine model of experimental pneumonia. As assessed by pulmonary clearance of H. influenzae, HMR 3004 was more effective (P < 0.05) than was azithromycin, ciprofloxacin, clarithromycin, erythromycin A, pristinamycin, or HMR 3647 in this model.

Sign in / Sign up

Export Citation Format

Share Document