scholarly journals Pharmacokinetics and serum bactericidal activity of vancomycin alone and in combination with ceftazidime in healthy volunteers.

1988 ◽  
Vol 32 (1) ◽  
pp. 92-95 ◽  
Author(s):  
M Boeckh ◽  
H Lode ◽  
K Borner ◽  
G Hoffken ◽  
J Wagner ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Bactericidal Activity ◽  
Serum Bactericidal Activity

Cefminox: correlation between in-vitro susceptibility and pharmacokinetics and serum bactericidal activity in healthy volunteers

1994 ◽  
Vol 33 (1) ◽  
pp. 91-101 ◽  
Author(s):  
L. Aguilar ◽  
C. Esteban ◽  
J. Frias ◽  
I. Pérez-Balcabao ◽  
A. J. Carcas ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Bactericidal Activity ◽  
In Vitro Susceptibility ◽  
Serum Bactericidal Activity

scholarly journals Pharmacodynamic effects of amoxicillin versus cefotaxime against penicillin-susceptible and penicillin-resistant pneumococcal strains: a phase I study.

1997 ◽  
Vol 41 (6) ◽  
pp. 1389-1391 ◽  
Author(s):  
L Aguilar ◽  
J Rosendo ◽  
I P Balcabao ◽  
M Martín ◽  
M J Giménez ◽  
...  
Keyword(s):  
Streptococcus Pneumoniae ◽  
Phase I ◽  
Healthy Volunteers ◽  
Bactericidal Activity ◽  
Resistant Strain ◽  
Phase I Study ◽  
Peak Level ◽  
Crossover Fashion ◽  
Activity Time ◽  
Serum Bactericidal Activity

Serum bactericidal activity against a penicillin-susceptible strain and a penicillin-resistant strain of Streptococcus pneumoniae (amoxicillin and cefotaxime MICs, 0.001 and 1 microg/ml, respectively, and MBCs, 0.01 and 2 microg/ml, respectively) was measured in 12 healthy volunteers who each received an oral 875-mg dose of amoxicillin and an intramuscular 1-g dose of cefotaxime in a crossover fashion. The areas under the bactericidal activity-time curves for the two strains were found to be similar for both antibiotics despite the significantly higher (P < 0.002) AUC/MIC and peak level/MIC values for cefotaxime.

scholarly journals Serum bactericidal activity of trovafloxacin, in combination with cefepime or amikacin, in healthy volunteers

2003 ◽  
Vol 9 (7) ◽  
pp. 670-677 ◽  
Author(s):  
A. Lubasch ◽  
S. Ziege ◽  
B. Brodersen ◽  
K. Borner ◽  
P. Koeppe ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Bactericidal Activity ◽  
Serum Bactericidal Activity
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