WE-AB-BRA-02: Study of the Therapeutic Effects of Pulsed Focused Ultrasound Combined with Encapsulated Chemotherapeutic Agents for Prostate Cancer in Vivo

2016 ◽  
Vol 43 (6Part38) ◽  
pp. 3791-3791
Author(s):  
L Chen ◽  
D Cvetkovic ◽  
X Chen ◽  
B Wang ◽  
R Gupta ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Focused Ultrasound ◽  
Chemotherapeutic Agents ◽  
Therapeutic Effects ◽  
Pulsed Focused Ultrasound

SU-F-J-225: Histology Study of MR Guided Pulsed Focused Ultrasound On Treatment of Prostate Cancer in Vivo

2016 ◽  
Vol 43 (6Part12) ◽  
pp. 3460-3461
Author(s):  
L Chen ◽  
D Cvetkovic ◽  
X Chen ◽  
B Wang ◽  
R Gupta ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Focused Ultrasound ◽  
Pulsed Focused Ultrasound

SU-E-T-245: MR Guided Focused Ultrasound Increased PARP Related Apoptosis On Prostate Cancer in Vivo

2014 ◽  
Vol 41 (6Part15) ◽  
pp. 279-280
Author(s):  
L Chen ◽  
X Chen ◽  
D Cvetkovic ◽  
R Gupta ◽  
D Yang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Focused Ultrasound

Heating of tissues in vivo by pulsed focused ultrasound to stimulate enhanced HSP expression

2011 ◽  
Author(s):  
Tamara Kujawska ◽  
Janusz Wójcik ◽  
Andrzej Nowicki ◽  
Yoichiro Matsumoto ◽  
Lawrence A. Crum ◽  
...  
Keyword(s):  
Focused Ultrasound ◽  
Pulsed Focused Ultrasound

scholarly journals A Review of the Potential of Phytochemicals from Prunus africana (Hook f.) Kalkman Stem Bark for Chemoprevention and Chemotherapy of Prostate Cancer

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Richard Komakech ◽  
Youngmin Kang ◽  
Jun-Hwan Lee ◽  
Francis Omujal
Keyword(s):  
Prostate Cancer ◽  
Cancer Cells ◽  
Treatment Options ◽  
Chemotherapeutic Agents ◽  
Sub Saharan Africa ◽  
In Vivo Studies ◽  
Prostate Cancer Cells ◽  
Prunus Africana

Prostate cancer remains one of the major causes of death worldwide. In view of the limited treatment options for patients with prostate cancer, preventive and treatment approaches based on natural compounds can play an integral role in tackling this disease. Recent evidence supports the beneficial effects of plant-derived phytochemicals as chemopreventive and chemotherapeutic agents for various cancers, including prostate cancer. Prunus africana has been used for generations in African traditional medicine to treat prostate cancer. This review examined the potential roles of the phytochemicals from P. africana, an endangered, sub-Saharan Africa plant in the chemoprevention and chemotherapy of prostate cancer. In vitro and in vivo studies have provided strong pharmacological evidence for antiprostate cancer activities of P. africana-derived phytochemicals. Through synergistic interactions between different effective phytochemicals, P. africana extracts have been shown to exhibit very strong antiandrogenic and antiangiogenic activities and have the ability to kill tumor cells via apoptotic pathways, prevent the proliferation of prostate cancer cells, and alter the signaling pathways required for the maintenance of prostate cancer cells. However, further preclinical and clinical studies ought to be done to advance and eventually use these promising phytochemicals for the prevention and chemotherapy of human prostate cancer.

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