WE-E-220-07: Therapeutic Effects of Pulsed Focused Ultrasound Enhancement of Docetaxel Combined with Radiotherapy on Prostate Cancer In Vivo

2011 ◽  
Vol 38 (6Part33) ◽  
pp. 3825-3825
Author(s):  
L Chen ◽  
Z Mu ◽  
X Chen ◽  
D Cvetkovic ◽  
A Pollack ◽  
...  
2018 ◽  
Author(s):  
Lili Chen ◽  
Alan Pollack

This project will determine whether (1) HIFU increases the cellular update of docetaxel in vivo, and (2) the increased uptake of docetaxel combined with RT will enhance tumor growth inhibition. We will determine the optimal HIFU parameters, quantify the update of docetaxel using a radioactive tritiated docetaxel and evaluate the efficacy of docetaxel+RT in inhibiting prostate tumor growth in vivo. This research has the potential to improve local control and may also have effects on distant microscopic disease by promoting immune response, which will also lay the foundation for other tumor models and studies on gene therapy and thrombolytic drugs.


2016 ◽  
Vol 43 (6Part12) ◽  
pp. 3460-3461
Author(s):  
L Chen ◽  
D Cvetkovic ◽  
X Chen ◽  
B Wang ◽  
R Gupta ◽  
...  

2014 ◽  
Vol 41 (6Part15) ◽  
pp. 279-280
Author(s):  
L Chen ◽  
X Chen ◽  
D Cvetkovic ◽  
R Gupta ◽  
D Yang ◽  
...  

2011 ◽  
Author(s):  
Tamara Kujawska ◽  
Janusz Wójcik ◽  
Andrzej Nowicki ◽  
Yoichiro Matsumoto ◽  
Lawrence A. Crum ◽  
...  

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