SU-E-T-245: MR Guided Focused Ultrasound Increased PARP Related Apoptosis On Prostate Cancer in Vivo

2014 ◽  
Vol 41 (6Part15) ◽  
pp. 279-280
Author(s):  
L Chen ◽  
X Chen ◽  
D Cvetkovic ◽  
R Gupta ◽  
D Yang ◽  
...  
2018 ◽  
Author(s):  
Lili Chen ◽  
Alan Pollack

This project will determine whether (1) HIFU increases the cellular update of docetaxel in vivo, and (2) the increased uptake of docetaxel combined with RT will enhance tumor growth inhibition. We will determine the optimal HIFU parameters, quantify the update of docetaxel using a radioactive tritiated docetaxel and evaluate the efficacy of docetaxel+RT in inhibiting prostate tumor growth in vivo. This research has the potential to improve local control and may also have effects on distant microscopic disease by promoting immune response, which will also lay the foundation for other tumor models and studies on gene therapy and thrombolytic drugs.


2008 ◽  
Vol 35 (6Part19) ◽  
pp. 2876-2876
Author(s):  
L Chen ◽  
Z Mu ◽  
P Hachem ◽  
L Chung ◽  
T Richardson ◽  
...  

2016 ◽  
Vol 43 (6Part12) ◽  
pp. 3460-3461
Author(s):  
L Chen ◽  
D Cvetkovic ◽  
X Chen ◽  
B Wang ◽  
R Gupta ◽  
...  

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