SU-F-J-225: Histology Study of MR Guided Pulsed Focused Ultrasound On Treatment of Prostate Cancer in Vivo

2016 ◽  
Vol 43 (6Part12) ◽  
pp. 3460-3461
Author(s):  
L Chen ◽  
D Cvetkovic ◽  
X Chen ◽  
B Wang ◽  
R Gupta ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Focused Ultrasound ◽  
Pulsed Focused Ultrasound

SU-E-T-245: MR Guided Focused Ultrasound Increased PARP Related Apoptosis On Prostate Cancer in Vivo

2014 ◽  
Vol 41 (6Part15) ◽  
pp. 279-280
Author(s):  
L Chen ◽  
X Chen ◽  
D Cvetkovic ◽  
R Gupta ◽  
D Yang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Focused Ultrasound

Heating of tissues in vivo by pulsed focused ultrasound to stimulate enhanced HSP expression

2011 ◽  
Author(s):  
Tamara Kujawska ◽  
Janusz Wójcik ◽  
Andrzej Nowicki ◽  
Yoichiro Matsumoto ◽  
Lawrence A. Crum ◽  
...  
Keyword(s):  
Focused Ultrasound ◽  
Pulsed Focused Ultrasound

scholarly journals MR Guided Pulsed High Intensity Focused Ultrasound Enhancement of Docetaxel Combined with Radiotherapy for Prostate Cancer Treatment

2018 ◽  
Author(s):  
Lili Chen ◽  
Alan Pollack
Keyword(s):  
Prostate Cancer ◽  
Gene Therapy ◽  
Tumor Growth ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Tumor Growth Inhibition ◽  
Prostate Cancer Treatment ◽  
Ultrasound Enhancement ◽  
Enhance Tumor Growth

This project will determine whether (1) HIFU increases the cellular update of docetaxel in vivo, and (2) the increased uptake of docetaxel combined with RT will enhance tumor growth inhibition. We will determine the optimal HIFU parameters, quantify the update of docetaxel using a radioactive tritiated docetaxel and evaluate the efficacy of docetaxel+RT in inhibiting prostate tumor growth in vivo. This research has the potential to improve local control and may also have effects on distant microscopic disease by promoting immune response, which will also lay the foundation for other tumor models and studies on gene therapy and thrombolytic drugs.

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