scholarly journals Functional photoacoustic tomography for non-invasive imaging of cerebral blood oxygenation and blood volume in rat brain in vivo

2005 ◽  
Author(s):  
Xueding Wang ◽  
Xueyi Xie ◽  
Geng Ku ◽  
George Stoica ◽  
Lihong V. Wang
Keyword(s):  
Rat Brain ◽  
Blood Volume ◽  
Blood Oxygenation ◽  
Photoacoustic Tomography ◽  
Non Invasive ◽  
Cerebral Blood Oxygenation

Non-invasive in vivo infrared laser spectroscopy to analyse endogenous oxy-haemoglobin, deoxy-haemoglobin, and blood volume in the rat CNS

2005 ◽  
Vol 145 (1-2) ◽  
pp. 11-22 ◽  
Author(s):  
Francesco Crespi ◽  
Andrea Bandera ◽  
Maurizio Donini ◽  
Christian Heidbreder ◽  
Luigi Rovati
Keyword(s):  
Blood Volume ◽  
Laser Spectroscopy ◽  
Infrared Laser ◽  
Non Invasive ◽  
Infrared Laser Spectroscopy ◽  
Rat Cns

Photoacoustic Tomography of a Nanoshell Contrast Agent in the in Vivo Rat Brain

Nano Letters ◽  
2004 ◽  
Vol 4 (9) ◽  
pp. 1689-1692 ◽  
Author(s):  
Yiwen Wang ◽  
Xueyi Xie ◽  
Xueding Wang ◽  
Geng Ku ◽  
Kelly L. Gill ◽  
...  
Keyword(s):  
Contrast Agent ◽  
Rat Brain ◽  
Photoacoustic Tomography

Suitability of [18F]Altanserin and PET to Determine 5-HT2A Receptor Availability in the Rat Brain: In Vivo and In Vitro Validation of Invasive and Non-Invasive Kinetic Models

2013 ◽  
Vol 15 (4) ◽  
pp. 456-467 ◽  
Author(s):  
Tina Kroll ◽  
David Elmenhorst ◽  
Andreas Matusch ◽  
Franziska Wedekind ◽  
Angela Weisshaupt ◽  
...  
Keyword(s):  
Rat Brain ◽  
Kinetic Models ◽  
Non Invasive

scholarly journals Quantitative Assessment of the Balance between Oxygen Delivery and Consumption in the Rat Brain after Transient Ischemia with T2-BOLD Magnetic Resonance Imaging

2002 ◽  
Vol 22 (3) ◽  
pp. 262-270 ◽  
Author(s):  
Mikko I. Kettunen ◽  
Olli H. J. Gröhn ◽  
M. Johanna Silvennoinen ◽  
Markku Penttonen ◽  
Risto A. Kauppinen
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Carotid Artery ◽  
Rat Brain ◽  
Blood Volume ◽  
Common Carotid Artery ◽  
Cerebral Blood Volume ◽  
Blood Oxygenation ◽  
Resonance Imaging ◽  
Transient Ischemia

The balance between oxygen consumption and delivery in the rat brain after exposure to transient ischemia was quantitatively studied with single-spin echo T2-BOLD (blood oxygenation level–dependent) magnetic resonance imaging at 4.7 T. The rats were exposed to graded common carotid artery occlusions using a modification of the four-vessel model of Pulsinelli. T2, diffusion, and cerebral blood volume were quantified with magnetic resonance imaging, and CBF was measured with the hydrogen clearance method. A transient common carotid artery occlusion below the CBF value of approximately 20 mL·100 g−1·min−1 was needed to yield a T2 increase of 4.6 ± 1.2 milliseconds (approximately 9% of cerebral T2) and 6.8 ± 1.7 milliseconds (approximately 13% of cerebral T2) after 7 and 15 minutes of ischemia, respectively. Increases in CBF of 103 ± 75% and in cerebral blood volume of 29 ± 20% were detected in the reperfusion phase. These hemodynamic changes alone could account for only approximately one third of the T2 increase in luxury perfusion, suggesting that a substantial increase in blood oxygen saturation (resulting from reduced oxygen extraction by the brain) is needed to explain the magnetic resonance imaging observation.

Sign in / Sign up

Export Citation Format

Share Document