Ultra-miniature (diameter: 6 mm, thickness: 5 mm) low-cost (price: 1,000 EUR) point-one-shot mid-infrared Fourier spectroscopic imager for ear clip type non-invasive blood glucose sensors

2019 ◽  
Author(s):  
Natsumi Kawashima ◽  
Satoru Adachi ◽  
Tomoya Kitazaki ◽  
Hanyue Kang ◽  
Akira Nishiyama ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Low Cost ◽  
Glucose Sensors ◽  
Cost Price ◽  
Mid Infrared ◽  
Non Invasive

scholarly journals Highly Sensitive Room-Temperature Sensor Based on Nanostructured K2W7O22 for Application in the Non-Invasive Diagnosis of Diabetes

Sensors ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 3703 ◽  
Author(s):  
Md Hossain ◽  
Qifeng Zhang ◽  
Michael Johnson ◽  
Danling Wang
Keyword(s):  
Blood Glucose ◽  
Detection Limit ◽  
Room Temperature ◽  
Detection System ◽  
Signal To Noise Ratio ◽  
Low Cost ◽  
Health Condition ◽  
Exhaled Breath ◽  
Glucose Levels ◽  
Non Invasive

Diabetes is one of the most rapidly-growing chronic diseases in the world. Acetone, a volatile organic compound in exhaled breath, shows a positive correlation with blood glucose and has proven to be a biomarker for type-1 diabetes. Measuring the level of acetone in exhaled breath can provide a non-invasive, low risk of infection, low cost, and convenient way to monitor the health condition of diabetics. There has been continuous demand for the improvement of this non-invasive, sensitive sensor system to provide a fast and real-time electronic readout of blood glucose levels. A novel nanostructured K2W7O22 has been recently used to test acetone with concentration from 0 parts-per-million (ppm) to 50 ppm at room temperature. The results revealed that a K2W7O22 sensor shows a sensitive response to acetone, but the detection limit is not ideal due to the limitations of the detection system of the device. In this paper, we report a K2W7O22 sensor with an improved sensitivity and detection limit by using an optimized circuit to minimize the electronic noise and increase the signal to noise ratio for the purpose of weak signal detection while the concentration of acetone is very low.

scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

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