Ultrasonic-assisted point-one-shot mid-infrared Fourier spectroscopy for realization of ear-clip type non-invasive blood glucose sensors: ultrasonic-assisted method for production of a reflection plane near the skin surface and detection of the blood glucose absorption peak in mice (2nd report)

2019 ◽  
Author(s):  
Natsumi Kawashima ◽  
Ichiro Ishimaru ◽  
Tomoya Kitazaki ◽  
Kosuke Nogo ◽  
Hanyue Kang ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Skin Surface ◽  
Glucose Absorption ◽  
Glucose Sensors ◽  
Absorption Peak ◽  
Fourier Spectroscopy ◽  
Mid Infrared ◽  
Non Invasive ◽  
Ultrasonic Assisted ◽  
Reflection Plane

Spectroscopic imaging of blood vessels only near the skin surface for non-invasive blood glucose measurement

2015 ◽  
Author(s):  
Masaru Fujiwara ◽  
Shun Sato ◽  
Pradeep K. W. Abeygunawardhana ◽  
Satoru Suzuki ◽  
Akira Nishiyama ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Vessels ◽  
Spectroscopic Imaging ◽  
Skin Surface ◽  
Blood Glucose Measurement ◽  
Glucose Measurement ◽  
Non Invasive

scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

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