scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

scholarly journals Towards Realisation of a Non-Invasive Blood Glucose Sensor Using Microstripline

2021 ◽  
Author(s):  
Samuel Zeising ◽  
Jens Kirchner ◽  
Hossein Fazeli Khalili ◽  
Doaa Ahmed ◽  
Maximilian Lübke ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Phase Change ◽  
Glucose Concentration ◽  
Glucose Sensor ◽  
Ground Plane ◽  
Glucose Sensors ◽  
Experimental Setup ◽  
Non Invasive ◽  
Matching Technique ◽  
Simulation Results

In this paper, the design of a microwave based noninvasive glucose sensor at the operating frequency of 19 GHz is presented. Worldwide, about 451 million adults suffer from diabetes. For optimal therapy, people with diabetes should monitor their blood glucose level continuously over the day. For that purpose non-invasive microwave based glucose sensors are under research. Non-invasive microwave based glucose sensors must automatically perform continuous measurements with a high and stable accuracy. However, there exists no reliable noninvasive microwave based glucose sensor up to now. The proposed sensor is designed based on a two-port microstripline (MSL) network. Water with various glucose concentration from 0 to 500 mg/dl is placed in a slot between the two ports. The simulation results show that the phase change in the reflection coefficient for the various glucose concentration depends on the matching. The measurement of the glucose concentration 10 mg/dl can be realized by applying a taper ground plane as a matching technique decreasing reflections at the interface between the microstripline substrate and the water. The proposed sensor achieves a sensitivity of 2 ° phase change per 10 mg/dl glucose concentration variation. In the future, the simulation results should be validated in an experimental setup. <br>

Affinity Viscosimetry Sensor for Enzyme Free Detection of Glucose in a Micro-Bioreaction Chamber

2016 ◽  
Vol 879 ◽  
pp. 1135-1140
Author(s):  
Thilo Liebscher ◽  
Franziska Glös ◽  
Andrea Böhme ◽  
M. Birkholz ◽  
M. di Vona ◽  
...  
Keyword(s):  
Glucose Concentration ◽  
Glucose Sensor ◽  
Time Measurement ◽  
Glucose Sensors ◽  
Cell Cultivation ◽  
New Approach ◽  
Microelectromechanical System ◽  
Long Time ◽  
Free Glucose

With the growing demand of miniaturization of cell cultivation a new approach towards measuring and sensing bio-analytes needs to be made due to the problem of small volumes (less than 150μl) containing small amounts of analytes. Most of the available glucose sensors monitor the glucose concentration with the help of enzymes, which become very inaccurate in terms of long time measurement and uses (i.e. consumes) glucose during the measurement becoming not available anymore for the cells. Therefore, we focused on applying an enzyme-free glucose sensor based on a microelectromechanical system (MEMS).

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