Absolute temperature measurements in optical tweezers by synchronized position and force measurement (Conference Presentation)

Author(s):  
Anatolii V. Kashchuk ◽  
Alexander B. Stilgoe ◽  
Timo A. Nieminen ◽  
Halina H. Rubinsztein-Dunlop
2016 ◽  
Vol 34 (1) ◽  
pp. 38 ◽  
Author(s):  
Sławomir Drobczyński ◽  
Kamila Duś-szachniewicz

2010 ◽  
Author(s):  
Jason Bundas ◽  
Richard Dennis ◽  
Kelly Patnaude ◽  
Douglas Burrows ◽  
Ross Faska ◽  
...  

2020 ◽  
Author(s):  
Kumiko Hayashi ◽  
Miki G. Miyamoto ◽  
Shinsuke Niwa

AbstractSynaptic cargo transport by kinesin and dynein in hippocampal neurons was investigated using non-invasive measurements of transport force based on non-equilibrium statistical mechanics. Although direct physical measurements such as force measurement using optical tweezers are difficult in an intracellular environment, the non-invasive estimations enabled enumerating force producing units (FPUs) carrying a cargo comprising the motor proteins generating force. The number of FPUs served as a barometer for stable and long-distance transport by multiple motors, which was then used to quantify the extent of damage to axonal transport by dynarrestin, a dynein inhibitor. We found that dynarrestin decreased the FPU for retrograde transport more than anterograde transport. In the future, these measurements may be used to quantify the damage to axonal transport resulting from neuronal diseases including Alzheimer’s, Parkinson’s, and Huntington’s diseases.


2021 ◽  
Vol 3 ◽  
Author(s):  
Johannes Boyer ◽  
Jakob Eckmann ◽  
Karl Strohmayer ◽  
Werner Koele ◽  
Moritz Federspiel ◽  
...  

Since the human body reacts to a variety of different diseases with elevated body temperature, measurement of body temperature remains relevant in clinical practice. The absolute temperature value for fever definition is still arbitrary and depends on the measuring site, as well as underlying disease and individual factors. Hence, a simple threshold for fever definition is outdated and a definition which relies on the relative changes in the individual seems reasonable as it takes these individual factors into account. In this prospective multicentric study we validate an adhesive axillary thermometer (SteadyTemp®) which allows continuous non-invasive temperature measurements. It consists of a patch to measure temperature and a smartphone application to process and visualize gathered data. This article provides information of the new diagnostic possibilities when using this wearable device and where it could be beneficial. Furthermore, it discusses how to interpret the generated data and when it is not practical to use, based on its characteristics and physiological phenomena.


Author(s):  
Christian Schmidt ◽  
Frank Altmann ◽  
Giorgio C. Mutinati ◽  
Elise Brunet ◽  
Stephan Steinhauer ◽  
...  

Abstract In this paper, investigations on absolute temperature measurements using IR-Thermography of CMOS integrated micro-hot-plates (μHP) are presented. The results of using two different approaches, emissivity correction and black paint coating, are presented and compared with respect to simulation and electrical testing results. In addition, FIB/SEM investigations were used for surface investigations and determination of possible influences to the thermal behaviour by black paint coating process.


2016 ◽  
Vol 34 (1) ◽  
pp. 2693
Author(s):  
Sławomir Drobczyński ◽  
Kamila Duś-szachniewicz

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