scholarly journals Construction of a BAC Contig Map of Chromosome 16q by Two-Dimensional Overgo Hybridization

2000 ◽  
Vol 10 (5) ◽  
pp. 714-721 ◽  
Author(s):  
C. S. Han
Genomics ◽  
2001 ◽  
Vol 74 (2) ◽  
pp. 129-141 ◽  
Author(s):  
Joomyeong Kim ◽  
Laurie Gordon ◽  
Paramvir Dehal ◽  
Hummy Badri ◽  
Mari Christensen ◽  
...  

Genomics ◽  
2002 ◽  
Vol 79 (3) ◽  
pp. 437-444 ◽  
Author(s):  
Andrew P Makrigiannis ◽  
Amanda T Pau ◽  
Pamela L Schwartzberg ◽  
Daniel W McVicar ◽  
Thomas W Beck ◽  
...  

2003 ◽  
Vol 102 (1-4) ◽  
pp. 189-195 ◽  
Author(s):  
A.L. Gustafson ◽  
R.L. Tallmadge ◽  
N. Ramlachan ◽  
D. Miller ◽  
H. Bird ◽  
...  

1999 ◽  
Vol 9 (8) ◽  
pp. 763-774 ◽  
Author(s):  
Yicheng Cao ◽  
Hyung Lyun Kang ◽  
Xuequn Xu ◽  
Mei Wang ◽  
So Hee Dho ◽  
...  

We have constructed a complete coverage BAC contig map that spans a 12-Mb genomic segment in the human chromosome 16p13.1–p11.2 region. The map consists of 68 previously mapped STSs and 289 BAC clones, 51 of which—corresponding to a total of 7.721 Mb of genomic DNA—have been sequenced, and provides a high resolution physical map of the region. Contigs were initially built based mainly on the analysis of STS contents and restriction fingerprint patterns of the clones. To close the gaps, probes derived from BAC clone ends were used to screen deeper BAC libraries. Clone end sequence data obtained from chromosome 16-specific BACs, as well as from public databases, were used for the identification of BACs that overlap with fully sequenced BACs by means of sequence match. This approach allowed precise alignment of clone overlaps in addition to restriction fingerprint comparison. A freehand contig drawing software tool was developed and used to manage the map data graphically and generate a real scale physical map. The map we present here is ∼3.5 × deep and provides a minimal tiling path that covers the region in an array of contigous, overlapping BACs.


2008 ◽  
Vol 120 (1-2) ◽  
pp. 164-172 ◽  
Author(s):  
C. Brinkmeyer-Langford ◽  
T. Raudsepp ◽  
A. Gustafson-Seabury ◽  
B.P. Chowdhary
Keyword(s):  

2004 ◽  
Vol 134 (4) ◽  
pp. 1317-1326 ◽  
Author(s):  
Jack Gardiner ◽  
Steven Schroeder ◽  
Mary L. Polacco ◽  
Hector Sanchez-Villeda ◽  
Zhiwei Fang ◽  
...  

1966 ◽  
Vol 24 ◽  
pp. 118-119
Author(s):  
Th. Schmidt-Kaler

I should like to give you a very condensed progress report on some spectrophotometric measurements of objective-prism spectra made in collaboration with H. Leicher at Bonn. The procedure used is almost completely automatic. The measurements are made with the help of a semi-automatic fully digitized registering microphotometer constructed by Hög-Hamburg. The reductions are carried out with the aid of a number of interconnected programmes written for the computer IBM 7090, beginning with the output of the photometer in the form of punched cards and ending with the printing-out of the final two-dimensional classifications.


1966 ◽  
Vol 24 ◽  
pp. 3-5
Author(s):  
W. W. Morgan

1. The definition of “normal” stars in spectral classification changes with time; at the time of the publication of theYerkes Spectral Atlasthe term “normal” was applied to stars whose spectra could be fitted smoothly into a two-dimensional array. Thus, at that time, weak-lined spectra (RR Lyrae and HD 140283) would have been considered peculiar. At the present time we would tend to classify such spectra as “normal”—in a more complicated classification scheme which would have a parameter varying with metallic-line intensity within a specific spectral subdivision.


1966 ◽  
Vol 25 ◽  
pp. 46-48 ◽  
Author(s):  
M. Lecar

“Dynamical mixing”, i.e. relaxation of a stellar phase space distribution through interaction with the mean gravitational field, is numerically investigated for a one-dimensional self-gravitating stellar gas. Qualitative results are presented in the form of a motion picture of the flow of phase points (representing homogeneous slabs of stars) in two-dimensional phase space.


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