An ordered BAC contig map of the equine major histocompatibility complex

2003 ◽  
Vol 102 (1-4) ◽  
pp. 189-195 ◽  
Author(s):  
A.L. Gustafson ◽  
R.L. Tallmadge ◽  
N. Ramlachan ◽  
D. Miller ◽  
H. Bird ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility ◽  
Bac Contig ◽  
Histocompatibility Complex ◽  
Contig Map

scholarly journals A BAC-based contig map of the cynomolgus macaque (Macaca fascicularis) major histocompatibility complex genomic region

Genomics ◽  
2007 ◽  
Vol 89 (3) ◽  
pp. 402-412 ◽  
Author(s):  
Atsushi Watanabe ◽  
Takashi Shiina ◽  
Sayoko Shimizu ◽  
Kazuyoshi Hosomichi ◽  
Kazuyo Yanagiya ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Macaca Fascicularis ◽  
Cynomolgus Macaque ◽  
Genomic Region ◽  
Major Histocompatibility ◽  
Histocompatibility Complex ◽  
Contig Map

Comparative Feline Genomics: A BAC/PAC Contig Map of the Major Histocompatibility Complex Class II Region

Genomics ◽  
2001 ◽  
Vol 71 (3) ◽  
pp. 282-295 ◽  
Author(s):  
Thomas W. Beck ◽  
J. Menninger ◽  
Ginny Voigt ◽  
Kimberly Newmann ◽  
Yoko Nishigaki ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Major Histocompatibility Complex Class ◽  
Class Ii ◽  
Complex Class ◽  
Major Histocompatibility ◽  
Histocompatibility Complex ◽  
Contig Map

Relationship of Major Histocompatibility Complex Class II Genes to Inhibitor Antibody Formation in Hemophilia A

1990 ◽  
Vol 64 (04) ◽  
pp. 564-568 ◽  
Author(s):  
Lloyd E Lippert ◽  
Lyman Mc A Fisher ◽  
Lawrence B Schook
Keyword(s):  
Major Histocompatibility Complex ◽  
Factor Viii ◽  
Antibody Formation ◽  
Rflp Analysis ◽  
Class Ii ◽  
Major Histocompatibility ◽  
Odds Ratios ◽  
Inhibitory Antibody ◽  
Histocompatibility Complex ◽  
Hla Dr

SummaryApproximately 14% of transfused hemophiliacs develop an anti-factor VIII inhibitory antibody which specifically neutralizes factor VIII procoagulant activity. In this study an association of the major histocompatibility complex (MHC) with inhibitor antibody formation was evaluated by restriction fragment length polymorphism (RFLP) analysis using BamHI, EcoRI, HindII, PstI, PvuII and TaqI digested genomic DNA probed with DP beta, DQ alpha, DQ beta and DR beta class II MHC gene probes. The RFLP patterns for 16 non-inhibitor and 11 inhibitor hemophiliac patients were analyzed. These 24 enzyme:probe combinations generated 231 fragments. Fifteen (15) fragments associated with the inhibitor phenotype; odds ratios ranged from 5.1 to 45 and lower bounds of 95% confidence intervals were > 1.000 for all 15 fragments. Five (5) fragments associated with non-inhibitors, with odds ratios ranging from 6.4 to 51.7. This report establishes a MHC related genetic basis for the inhibitor phenotype. No statistically significant differences in the distribution of serologically defined HLA-DR phenotypes were observed between the inhibitor and non-inhibitor groups.

Association of susceptibility to spontaneous diabetes in rat with genes of major histocompatibility complex

Diabetes ◽  
1988 ◽  
Vol 37 (10) ◽  
pp. 1438-1443 ◽  
Author(s):  
E. Colle ◽  
S. J. Ono ◽  
A. Fuks ◽  
R. D. Guttmann ◽  
T. A. Seemayer
Keyword(s):  
Major Histocompatibility Complex ◽  
Spontaneous Diabetes ◽  
Major Histocompatibility ◽  
Histocompatibility Complex
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