The Major Inorganic Constituents of Adult Drosophila melanogaster

1957 ◽  
Vol 91 (860) ◽  
pp. 319-319 ◽  
Author(s):  
R. C. King
2013 ◽  
Vol 77 (4) ◽  
pp. 836-838 ◽  
Author(s):  
Shigenobu SHIOTANI ◽  
Nobuya YANAI ◽  
Takanori SUZUKI ◽  
Shiho TUJIOKA ◽  
Yurie SAKANO ◽  
...  

2008 ◽  
Vol 36 (6) ◽  
pp. 1389-1392 ◽  
Author(s):  
Gemma S. Beard ◽  
Joanna M. Bridger ◽  
Ian R. Kill ◽  
David R.P. Tree

The laminopathy Hutchinson–Gilford progeria syndrome (HGPS) is caused by the mutant lamin A protein progerin and leads to premature aging of affected children. Despite numerous cell biological and biochemical insights into the basis for the cellular abnormalities seen in HGPS, the mechanism linking progerin to the organismal phenotype is not fully understood. To begin to address the mechanism behind HGPS using Drosophila melanogaster, we have ectopically expressed progerin and lamin A. We found that ectopic progerin and lamin A phenocopy several effects of laminopathies in developing and adult Drosophila, but that progerin causes a stronger phenotype than wild-type lamin A.


1965 ◽  
Vol 20 (4) ◽  
pp. 292-297 ◽  
Author(s):  
Robert C. King ◽  
Dietrich Bodenstein

Ovarian tumors are characteristically found in adult Drosophila melanogaster females homozygous for certain recessive genes (fes, nw and fu). Ovaries genetically destined to become tumorous do so even when they are transplanted to a normal abdomen. Normal ovaries transplanted to the abdomen of females homozygous for such tumor genes do not become tumorous. Therefore there is no evidence for diffusible tumorigenic agents as initiating factors in the development of the ovarian tumors characteristic of females homozygous for fes, nw or fu. Vitellogenesis is retarded in adult females homozygous for certain recessive genes (fs 2.1, ty and ap4). Transplantation of ovaries from homozygous females to the abdominal body cavity of females carrying the + alleles of the gene in question fails to cure the implant in the case of fs 2.1 and ty. Ovaries of ap4/ap4 genotype produce abundant yolk when implanted into wild type abdomens. Thus it is the abdominal environment of ap4 which is at fault, rather than a malfunctioning of the ovary.


2005 ◽  
Vol 15 (22) ◽  
pp. 2063-2068 ◽  
Author(s):  
Johannes H. Bauer ◽  
Peter C. Poon ◽  
Heather Glatt-Deeley ◽  
John M. Abrams ◽  
Stephen L. Helfand

2008 ◽  
Vol 169 (6) ◽  
pp. 707-711 ◽  
Author(s):  
Vijay Parashar ◽  
Stewart Frankel ◽  
Alan G. Lurie ◽  
Blanka Rogina

1981 ◽  
Vol 113 (4) ◽  
pp. 315-323 ◽  
Author(s):  
S. S. Chawla ◽  
J.-M. Perron ◽  
C. Radouco-Thomas

AbstractAn apparatus consisting of a plastic box and a feeding circuit permits the calculation of μl volumes of ethanol ingested by Drosophila melanogaster Meigen. The net amount of ethanol taken (expressed in 100% ethanol) has been examined in various experimental conditions: sucrose solutions, ethanol–sucrose solutions at various sucrose and alcohol concentrations, ethanol solutions - cube of sucrose and ethanol solutions alone. The data obtained on ingestion by Drosophila show that the consumption of sucrose solutions was inversely proportional to the concentrations of sucrose. The amount of ethanol ingested during 14 days was directly related to the concentration of ethanol in the diets although in general the total volume of solution consumed did not vary significantly in most cases. The analyses of observations of 14 days showed that decreased mortality was obtained with the rise in the concentration of sucrose in sucrose-water solutions in 0.5–3% range and the mortality increased with the rise in the concentration of ethanol in the diets, yet ethanol-sucrose was better than cube of sugar alone.


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