Effect of membrane charge density on the protein corona of cationic liposomes: Interplay between cationic charge and surface area

2011 ◽  
Vol 99 (3) ◽  
pp. 033702 ◽  
Author(s):  
Giulio Caracciolo ◽  
Daniela Pozzi ◽  
Sofia Candeloro De Sanctis ◽  
Anna Laura Capriotti ◽  
Giuseppe Caruso ◽  
...  
Keyword(s):  
Charge Density ◽  
Surface Area ◽  
Protein Corona ◽  
Cationic Liposomes ◽  
Membrane Charge

scholarly journals Anomalous Thermo-osmotic Conversion Performance of Ionic Covalent-Organic-Framework Membranes in Response to Charge Variations

2022 ◽  
Author(s):  
Qi Sun ◽  
Weipeng Xian ◽  
Xiuhui Zuo ◽  
Changjia Zhu ◽  
Qing Guo ◽  
...  
Keyword(s):  
Charge Density ◽  
Energy Conversion ◽  
Energy Demand ◽  
High Performance ◽  
Critical Factor ◽  
Energy Conversion Efficiency ◽  
Nanoporous Membranes ◽  
Power Extraction ◽  
Membrane Charge ◽  
Salinity Difference

Abstract The development of efficient thermo-osmotic energy conversion devices has fascinated scientists and engineers for several decades in terms of satisfying the growing energy demand. The fabrication of ionic membranes with a high charge population is known to be a critical factor in the design of high-performance power generators for achieving high permselectivity and, consequently, high power extraction efficiency. Herein, we experimentally demonstrated that the thermo-osmotic energy conversion efficiency was improved by increasing the membrane charge density; however, this enhancement occurred only within a narrow window and subsequently exhibited a plateau over a threshold density. The complex interplay between pore−pore interactions and fluid structuration for ion transport across the upscaled nanoporous membranes helped explain the obtained results with the aid of numerical simulations. Consequently, the power generation efficiency of the multipore membrane deteriorated, deviating considerably from the case of simple linear extrapolation of the behavior of the single-pore counterparts. A plateau in the output electric power was observed at a moderate charge density, affording a value of 210 W m−2 at a 50-fold salinity difference with a temperature gradient of 40 K. This study has far-reaching implications for discerning an optimal range of membrane charge populations for augmenting the energy extraction, rather than intuitively focusing on achieving high densities.

scholarly journals Hybrid Monolith of Graphene/TEMPO-Oxidized Cellulose Nanofiber as Mechanically Robust, Highly Functional, and Recyclable Adsorbent of Methylene Blue Dye

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Asif Hussain ◽  
Jiebing Li ◽  
Jun Wang ◽  
Fei Xue ◽  
Yundan Chen ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Specific Surface ◽  
Charge Density ◽  
Surface Charge ◽  
Surface Area ◽  
Specific Surface Area ◽  
Surface Charge Density ◽  
Cellulose Nanofibers ◽  
Maximum Adsorption Capacity ◽  
Assembly Method

Herein we demonstrate first report on fabrication, characterization, and adsorptive appraisal of graphene/cellulose nanofibers (GO/CNFs) monolith for methylene blue (MB) dye. Series of hybrid monolith (GO/CNFs) were assembled via urea assisted self-assembly method. Hybrid materials were characterized by scanning electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction patterns, Raman spectroscopy, elemental analysis, thermogravimetric curve analysis, specific surface area, surface charge density measurement, and compressional mechanical analysis. It was proposed that strong chemical interaction (mainly hydrogen bonding) was responsible for the formation of hybrid assembly. GO/CNFs monolith showed mechanically robust architecture with tunable pore structure and surface properties. GO/CNFs adsorbent could completely remove trace to moderate concentrations of MB dye and follow pseudo-second-order kinetics model. Adsorption isotherm behaviors were found in the following order: Langmuir isotherm > Freundlich isotherm > Temkin isotherm model. Maximum adsorption capacity of 227.27 mg g−1 was achieved which is much higher than reported graphene based monoliths and magnetic adsorbent. Incorporation of nanocellulose follows exponential relationship with dye uptake capacities. High surface charge density and specific surface area were main dye adsorptive mechanism. Regeneration and recycling efficiency was achieved up to four consecutive cycles with cost-effective recollection and zero recontamination of treated water.

Technical and Practical Aspects of Invasive Recordings and Brain Stimulation

2018 ◽  
pp. 26-37
Author(s):  
Gholam K. Motamedi ◽  
Jean Gotman ◽  
Ronald P. Lesser
Keyword(s):  
Charge Density ◽  
Surface Area ◽  
Brain Stimulation ◽  
Electrode Surface ◽  
Cortical Stimulation ◽  
Basic Principles ◽  
Depth Electrodes ◽  
Cortical Stimulation Mapping ◽  
Drug Resistant Epilepsy ◽  
Intracranial Electrodes

This chapter discusses the technical and practical issues involved in invasive recording and cortical stimulation mapping in patients with drug-resistant epilepsy. It reviews the way in which EEG signals are generated, circumstances when intracranial electrodes are needed, and how such electrodes operate. It also discusses the basic principles of cortical stimulation mapping and different methods of using intracranial electrodes for stimulation purposes, and relevant concepts involved in the process such as charge density and electrode surface area. It reviews different electrodes used for mapping including subdural surface electrodes and depth electrodes.

Toxicity and mechanism of mesoporous silica nanoparticles in eyes

Nanoscale ◽  
2020 ◽  
Vol 12 (25) ◽  
pp. 13637-13653 ◽  
Author(s):  
Xia Chen ◽  
Shuang Zhu ◽  
Xisu Hu ◽  
Dayu Sun ◽  
Junling Yang ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Surface Area ◽  
Dry Eye ◽  
Mesoporous Silica Nanoparticles ◽  
Protein Corona ◽  
Large Surface Area ◽  
Corneal Damage

It aims to explore the toxicity and mechanism of large-surface-area MSiNPs and MSiNPs-Ag+ exposed to hCEC cells and cornea. A protein corona-based therapy was proposed to treat MSiNPs and MSiNPs-Ag+ induced corneal damage and dry eye.

Surface area of lipid membranes regulates the DNA-binding capacity of cationic liposomes

2009 ◽  
Vol 94 (3) ◽  
pp. 033903 ◽  
Author(s):  
Cristina Marchini ◽  
Maura Montani ◽  
Augusto Amici ◽  
Daniela Pozzi ◽  
Ruggero Caminiti ◽  
...  
Keyword(s):  
Dna Binding ◽  
Surface Area ◽  
Lipid Membranes ◽  
Binding Capacity ◽  
Cationic Liposomes

Chromatographic Charge Density Determination of Materials with Low Surface Area

Langmuir ◽  
1994 ◽  
Vol 10 (3) ◽  
pp. 855-860 ◽  
Author(s):  
Christa S. Buergisser ◽  
Andre M. Scheidegger ◽  
Michal Borkovec ◽  
Hans Sticher
Keyword(s):  
Charge Density ◽  
Surface Area ◽  
Density Determination

scholarly journals Electrophoretic Mobility and N-Acetyl Neuraminic Acid Content of Human Normal and Leukemic Lymphocytes and Granulocytes

Blood ◽  
1970 ◽  
Vol 35 (1) ◽  
pp. 12-22 ◽  
Author(s):  
MARSHALL A. LICHTMAN ◽  
ROBERT I. WEED
Keyword(s):  
Charge Density ◽  
Surface Charge ◽  
Surface Area ◽  
Electrophoretic Mobility ◽  
Surface Charge Density ◽  
Human Leukocyte ◽  
Neuraminic Acid ◽  
Cell Periphery ◽  
Neuraminidase Treatment ◽  
Molecular Arrangement

Abstract Studies have been conducted to determine the electrophoretic mobility and the N-Acetyl Neuraminic Acid (NANA) content of different human leukocyte types. Leukemic granulocytes and lymphocytes do not differ significantly from their normal counterparts in rate of electrophoretic mobility. An absolute comparison between leukemic and normal myeloblasts could not be made; however, populations of leukemic myeloblasts were often similar in mobility to normal immature granulocytes. Immature granulocytes had a significantly higher surface-charge density than PMNGs, and this is due primarily to differences in NANA carboxyl groups contributing to the electro-kinetic surface of the cell. The small lymphocyte has a surface-charge density more similar to that of immature granulocytes and myeloblasts than to that of PMNGs. The surface-dependent behavior of different leukocyte types may be related, in part, to the density or arrangement of NANA molecules at the cell periphery; alternatively, the distribution of surface NANA may be a reflection of other differences in molecular arrangement of the cell membrane which are important in determining functional capacities. Total cellular NANA is greater in the PMNG than the lymphocyte, and this is likely to be a reflection of the larger surface area of external and internal membranes of the PMNG. These data also suggest that the surface area of the PMNG and lymphocyte is not reflected by the assumption of a smooth sphere. Neither total NANA nor neuraminidase-susceptible NANA can be used as an estimate of comparative NANA-dependent surface-charge density which must depend on electrophoretic mobility measurements with and without neuraminidase treatment.

Enhanced Transfection Efficiency of Multicomponent Lipoplexes in the Regime of Optimal Membrane Charge Density

2008 ◽  
Vol 112 (36) ◽  
pp. 11298-11304 ◽  
Author(s):  
Giulio Caracciolo ◽  
Daniela Pozzi ◽  
Ruggero Caminiti ◽  
Cristina Marchini ◽  
Maura Montani ◽  
...  
Keyword(s):  
Charge Density ◽  
Transfection Efficiency ◽  
Membrane Charge
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