Recent advances in integrated solid-state nanopore sensors

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Md. Mahmudur Rahman ◽  
Mohammad Julker Neyen Sampad ◽  
Aaron Hawkins ◽  
Holger Schmidt
Keyword(s):  
Solid State ◽  
Single Molecule ◽  
Life Science ◽  
New Class ◽  
Recent Advances ◽  
On Chip ◽  
Nanopore Sensors

The advent of single-molecule probing techniques has revolutionized the biomedical and life science fields and has spurred the development of a new class of labs-on-chip based on powerful biosensors. Nanopores...

scholarly journals Ultrahigh areal number density solid-state on-chip microsupercapacitors via electrohydrodynamic jet printing

2020 ◽  
Vol 6 (10) ◽  
pp. eaaz1692 ◽  
Author(s):  
Kwon-Hyung Lee ◽  
Seong-Sun Lee ◽  
David B. Ahn ◽  
Jaehyun Lee ◽  
Doyoung Byun ◽  
...  
Keyword(s):  
Solid State ◽  
Operating Voltage ◽  
Number Density ◽  
Chip Area ◽  
New Class ◽  
Electrohydrodynamic Jet Printing ◽  
Unit Cells ◽  
In Series ◽  
Jet Printing ◽  
On Chip

Microsupercapacitors (MSCs) have garnered considerable attention as a promising power source for microelectronics and miniaturized portable/wearable devices. However, their practical application has been hindered by the manufacturing complexity and dimensional limits. Here, we develop a new class of ultrahigh areal number density solid-state MSCs (UHD SS–MSCs) on a chip via electrohydrodynamic (EHD) jet printing. This is, to the best of our knowledge, the first study to exploit EHD jet printing in the MSCs. The activated carbon-based electrode inks are EHD jet-printed, creating interdigitated electrodes with fine feature sizes. Subsequently, a drying-free, ultraviolet-cured solid-state gel electrolyte is introduced to ensure electrochemical isolation between the SS–MSCs, enabling dense SS–MSC integration with on-demand (in-series/in-parallel) cell connection on a chip. The resulting on-chip UHD SS–MSCs exhibit exceptional areal number density [36 unit cells integrated on a chip (area = 8.0 mm × 8.2 mm), 54.9 cells cm−2] and areal operating voltage (65.9 V cm−2).

Solid-state nanopores for biosensing with submolecular resolution

2012 ◽  
Vol 40 (4) ◽  
pp. 624-628 ◽  
Author(s):  
Azadeh Bahrami ◽  
Fatma Doğan ◽  
Deanpen Japrung ◽  
Tim Albrecht
Keyword(s):  
Solid State ◽  
Dna Sequencing ◽  
Single Molecule ◽  
Dna Interactions ◽  
Patch Clamp Technique ◽  
New Class ◽  
Protein Dna Interactions ◽  
Transmembrane Pores ◽  
Recent Developments ◽  
Detection Of Biomolecules

Biological cell membranes contain various types of ion channels and transmembrane pores in the 1–100 nm range, which are vital for cellular function. Individual channels can be probed electrically, as demonstrated by Neher and Sakmann in 1976 using the patch-clamp technique [Neher and Sakmann (1976) Nature 260, 799–802]. Since the 1990s, this work has inspired the use of protein or solid-state nanopores as inexpensive and ultrafast sensors for the detection of biomolecules, including DNA, RNA and proteins, but with particular focus on DNA sequencing. Solid-state nanopores in particular have the advantage that the pore size can be tailored to the analyte in question and that they can be modified using semi-conductor processing technology. This establishes solid-state nanopores as a new class of single-molecule biosensor devices, in some cases with submolecular resolution. In the present review, we discuss a few of the most important recent developments in this field and how they might be applied to studying protein–protein and protein–DNA interactions or in the context of ultra-fast DNA sequencing.

Single Molecule Solid State Light Emitting Electrochemical Cells with Lifetimes Superior to 3000 Hours

2008 ◽  
Author(s):  
Henk Bolink ◽  
Rubén D. Costa ◽  
Enrique Orti ◽  
Michele Sessolo ◽  
Stefan Graber ◽  
...  
Keyword(s):  
Solid State ◽  
Single Molecule ◽  
Electrochemical Cells ◽  
Light Emitting

Solid-state fermentation for enhancing the nutraceutical content of agrifood by-products: Recent advances and its industrial feasibility

2021 ◽  
pp. 100926
Author(s):  
Luis O. Cano y Postigo ◽  
Daniel A. Jacobo-Velázquez ◽  
Daniel Guajardo-Flores ◽  
Luis Eduardo Garcia Amezquita ◽  
Tomás García-Cayuela
Keyword(s):  
Solid State ◽  
Solid State Fermentation ◽  
Recent Advances ◽  
By Products

scholarly journals Solid‐State Near‐Infrared Circularly Polarized Luminescence from Chiral YbIII‐Single‐Molecule Magnet

2021 ◽  
Author(s):  
Fabrice Pointillart ◽  
Bertrand Lefeuvre ◽  
Carlo Andrea Mattei ◽  
Jessica Flores Gonzalez ◽  
Frédéric Gendron ◽  
...  
Keyword(s):  
Solid State ◽  
Single Molecule ◽  
Near Infrared ◽  
Circularly Polarized ◽  
Single Molecule Magnet ◽  
Circularly Polarized Luminescence ◽  
Polarized Luminescence

Recent advances in eye-safe Er:YAG solid-state heat-capacity technology

2012 ◽  
Author(s):  
Marc Eichhorn ◽  
Stefano Bigotta ◽  
Thierry Ibach
Keyword(s):  
Heat Capacity ◽  
Solid State ◽  
State Heat ◽  
Recent Advances

scholarly journals Single-molecule protein identification by sub-nanopore sensors

2017 ◽  
Vol 13 (5) ◽  
pp. e1005356 ◽  
Author(s):  
Mikhail Kolmogorov ◽  
Eamonn Kennedy ◽  
Zhuxin Dong ◽  
Gregory Timp ◽  
Pavel A. Pevzner
Keyword(s):  
Single Molecule ◽  
Protein Identification ◽  
Nanopore Sensors

Measuring Trapped DNA at the Liquid-Air Interface for Enhanced Single Molecule Sensing

Nanoscale ◽  
2021 ◽  
Author(s):  
Nasim Farajpour ◽  
Lauren Lastra ◽  
Vinay Sharma ◽  
Kevin Freedman
Keyword(s):  
Solid State ◽  
Single Molecule ◽  
Borosilicate Glass ◽  
Low Noise ◽  
Viable Alternative ◽  
Single Molecule Detection ◽  
Widespread Application ◽  
Promising Tool ◽  
Air Interface ◽  
Cost Efficient

Nanopore sensing is a promising tool with widespread application in single-molecule detection. Borosilicate glass nanopores are a viable alternative to other solid-state nanopores due to low noise and cost-efficient fabrication....

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