Molecular Rotors as Reporters for Viscosity of Solutions of Collagen Like Peptides

2021 ◽  
Author(s):  
Christopher McTiernan ◽  
Matias Zuñiga-Bustos ◽  
Roberto Rosales-Rojas ◽  
Pablo Barrias ◽  
May Griffith ◽  
...  
Keyword(s):  
Steady State ◽  
Fluorometric Assay ◽  
Molecular Rotors ◽  
Molecular Rotor

We have studied the suitability of using a molecular rotor-based steady-state fluorometric assay for evaluating changes in both the conformation and the viscosity of collagen-like peptide solutions. Our results indicate...

Predicting lanthanide boride inverse sandwich tubular molecular rotors with the smallest core–shell structure

Nanoscale ◽  
2019 ◽  
Vol 11 (44) ◽  
pp. 21311-21316 ◽  
Author(s):  
Xiao-Qin Lu ◽  
Qiang Chen ◽  
Xin-Xin Tian ◽  
Yue-Wen Mu ◽  
Hai-Gang Lu ◽  
...  
Keyword(s):  
First Principles ◽  
Shell Structure ◽  
Molecular Rotors ◽  
Core Shell ◽  
Molecular Rotor ◽  
Sandwich Complexes ◽  
Core Shell Structure

Extensive first-principles theory calculations predict the possibility of bi-decker inverse sandwich complexes La2[B18], La2[B18]2−, and La2[B2@B18], with the B2-centered La2[B2@B18] as a tubular molecular rotor possessing the smallest core–shell structure.

scholarly journals The effect of structural heterogeneity upon the microviscosity of ionic liquids

2020 ◽  
Vol 11 (24) ◽  
pp. 6121-6133 ◽  
Author(s):  
Ryan Clark ◽  
Mohd A. Nawawi ◽  
Ana Dobre ◽  
David Pugh ◽  
Qingshan Liu ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Ionic Liquids ◽  
Bulk Viscosity ◽  
Structural Heterogeneity ◽  
Molecular Rotors ◽  
Complex Relationship ◽  
Molecular Rotor ◽  
Time Resolved Fluorescence ◽  
Time Resolved

The behaviour of two molecular rotors have been studied in various ionic liquids. Time resolved fluorescence shows a complex relationship between the bulk viscosity of the ionic liquid and microstructure of solvent around each molecular rotor.

Precision Assessment of Biofluid Viscosity Measurements Using Molecular Rotors

2005 ◽  
Vol 127 (3) ◽  
pp. 450-454 ◽  
Author(s):  
Walter J. Akers ◽  
Mark A. Haidekker
Keyword(s):  
Fluorescence Emission ◽  
High Viscosity ◽  
Plasma Viscosity ◽  
Molecular Rotors ◽  
Solution Viscosity ◽  
Human Blood Plasma ◽  
Fluid Viscosity ◽  
Molecular Rotor ◽  
Test Set ◽  
Precision Assessment

Blood viscosity changes with many pathologic conditions, but its importance has not been fully investigated because the current methods of measurement are poorly suited for clinical applications. The use of viscosity-sensitive fluorescent molecular rotors to determine fluid viscosity in a nonmechanical manner has been investigated recently, but it is unknown how the precision of the fluorescence-based method compares to established mechanical viscometry. Human blood plasma viscosity was modulated with high-viscosity plasma expanders, dextran, pentastarch, and hetastarch. The samples were divided into a calibration and a test set. The relationship between fluorescence emission and viscosity was established using the calibration set. Viscosity of the test set was determined by fluorescence and by cone-and-plate viscometer, and the precision of both methods compared. Molecular rotor fluorescence intensity showed a power law relationship with solution viscosity. Mechanical measurements deviated from the theoretical viscosity value by less than 7.6%, while fluorescence-based measurements deviated by less than 6%. The average coefficient of variation was 6.9% (mechanical measurement) and 3.4% to 3.8% (fluorescence-based measurement, depending on the molecular rotor used). Fluorescence-based viscometry exhibits comparable precision to mechanical viscometry. Fluorescence viscometry does not apply shear and is therefore more practical for biofluids which have apparent non-Newtonian properties. In addition, fluorescence instrumentation makes very fast serial measurements possible, thus promising new areas of application in laboratory and clinical settings.

scholarly journals Measuring viscosity inside mesoporous silica using protein-bound molecular rotor probe

2018 ◽  
Vol 20 (36) ◽  
pp. 23202-23213 ◽  
Author(s):  
Pegah S. Nabavi Zadeh ◽  
Milene Zezzi do Valle Gomes ◽  
Maria Abrahamsson ◽  
Anders E. C. Palmqvist ◽  
Björn Åkerman
Keyword(s):  
Mesoporous Silica ◽  
Fluorescence Spectroscopy ◽  
Effective Viscosity ◽  
Molecular Rotors ◽  
Molecular Rotor

Fluorescence spectroscopy of protein-bound molecular rotors Cy3 and Cy5 is used to monitor the effective viscosity inside the pores of two types of mesoporous silica (SBA-15 and MCF) with pore diameters between 8.9 and 33 nm.

CO2 regulates molecular rotor dynamics in porous materials

2017 ◽  
Vol 53 (55) ◽  
pp. 7776-7779 ◽  
Author(s):  
S. Bracco ◽  
T. Miyano ◽  
M. Negroni ◽  
I. Bassanetti ◽  
L. Marchio' ◽  
...  
Keyword(s):  
Porous Materials ◽  
Molecular Crystals ◽  
Rotor Dynamics ◽  
Molecular Rotors ◽  
Molecular Rotor

Porous molecular crystals contain fast molecular rotors whose dynamics can be controlled by CO2.

A ferroelastic molecular rotor crystal showing inverse temperature symmetry breaking

2021 ◽  
Author(s):  
Le-Ping Miao ◽  
Lin-Lin Chu ◽  
Xiang-Bin Han ◽  
Bei-Dou Liang ◽  
Chao-Yang Chai ◽  
...  
Keyword(s):  
Symmetry Breaking ◽  
Smart Materials ◽  
Molecular Crystals ◽  
Molecular Rotors ◽  
Inverse Temperature ◽  
Next Generation ◽  
Molecular Rotor ◽  
Dynamic Materials ◽  
Typical Type

Functional dynamic molecular crystals have drawn increasing interest in exploring next-generation flexible and smart materials. Molecular rotors, as a typical type of dynamic materials, are good candidates to exhibit bulk...

scholarly journals Push–pull dioxaborine as fluorescent molecular rotor: far-red fluorogenic probe for ligand–receptor interactions

2016 ◽  
Vol 4 (14) ◽  
pp. 3002-3009 ◽  
Author(s):  
Iuliia A. Karpenko ◽  
Yosuke Niko ◽  
Viktor P. Yakubovskyi ◽  
Andriy O. Gerasov ◽  
Dominique Bonnet ◽  
...  
Keyword(s):  
Molecular Rotors ◽  
Live Cells ◽  
Molecular Rotor ◽  
Solvatochromic Dyes ◽  
Fluorogenic Probe ◽  
Receptor Interactions ◽  
Fluorogenic Probes ◽  
Detection Of Biomolecules

Fluorescent solvatochromic dyes and molecular rotors have attracted considerable attention as fluorogenic probes because of background-free detection of biomolecules in live cells in no-wash conditions.

scholarly journals Ultrasensitive recognition of AP sites in DNA at the single-cell level: one molecular rotor sequentially self-regulated to form multiple different stable conformations

2019 ◽  
Vol 10 (44) ◽  
pp. 10373-10380 ◽  
Author(s):  
Beidou Feng ◽  
Kui Wang ◽  
Yonggang Yang ◽  
Ge Wang ◽  
Hua Zhang ◽  
...  
Keyword(s):  
Single Cell ◽  
Molecular Rotors ◽  
Single Cell Level ◽  
Molecular Rotor ◽  
Cell Level ◽  
Ap Sites

Molecular rotors self-regulate their conformations to emit different ultrasensitive recognition signals for AP sites in DNA at the single-cell level.

scholarly journals Two ‘braking mechanisms’ for Tin phthalocyanine molecular rotor on dipolar oxide iron surface

2022 ◽  
Author(s):  
Shuangzan Lu ◽  
Min Huang ◽  
Guodong Huang ◽  
Qinmin Guo ◽  
Hongxing Li ◽  
...  
Keyword(s):  
Iron Surface ◽  
Molecular Rotors ◽  
Molecular Rotor

Manipulation of artificial molecular rotors/motors is a key issue in the field of molecular nanomachine. Here we assemble non-planar SnPc molecules on FeO film to form two kinds of rotors...

Tuning rotation axes of single molecular rotors by a combination of single-atom manipulation and single-molecule chemistry

2020 ◽  
Vol 56 (6) ◽  
pp. 968-971 ◽  
Author(s):  
Tianhao Wu ◽  
Liwei Liu ◽  
Yajie Zhang ◽  
Yifan Wang ◽  
Ziyong Shen ◽  
...  
Keyword(s):  
Single Molecule ◽  
Molecular Rotors ◽  
Single Atom ◽  
Molecular Rotor ◽  
Rotation Axes ◽  
Atom Manipulation

Tin-phthalocyanine acts as a molecular rotor on the Ag(111) surface with four different rotational axes from the center to the periphery of the molecule.

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