Water stable nanocoatings of poly(N-isopropylacrylamide)-based block copolymers on culture insert membranes for temperature-controlled cell adhesion

2020 ◽  
Vol 8 (34) ◽  
pp. 7812-7821 ◽  
Author(s):  
Masamichi Nakayama ◽  
Yuki Toyoshima ◽  
Hiroshi Chinen ◽  
Akihiko Kikuchi ◽  
Masayuki Yamato ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Block Copolymers ◽  
Spin Coating ◽  
Thermal Cell ◽  
Temperature Controlled

We report the facile and stable fabrication of thermoresponsive culture inserts by spin-coating poly(N-isopropylacrylamide)-based block copolymers for thermal cell adhesion/detachment control.

Selective Cell Adhesion and Biosensing Applications of Bio-Active Block Copolymers Prepared by CuAAC/Thiol-ene Double Click Reactions

2015 ◽  
Vol 15 (9) ◽  
pp. 1233-1241 ◽  
Author(s):  
Gizem Oyman Eyrilmez ◽  
Sean Doran ◽  
Eljesa Murtezi ◽  
Bilal Demir ◽  
Dilek Odaci Demirkol ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Block Copolymers ◽  
Click Reactions ◽  
Active Block

scholarly journals In Vitro and In Vivo Studies of Biodegradability and Biocompatibility of Poly(εCL)-b-Poly(EtOEP)-Based Films

Polymers ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3039
Author(s):  
Ilya Nifant’ev ◽  
Andrey Shlyakhtin ◽  
Pavel Komarov ◽  
Alexander Tavtorkin ◽  
Evgeniya Kananykhina ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Block Copolymers ◽  
Polymer Films ◽  
Hydrolytic Stability ◽  
Polymer Materials ◽  
In Vivo Studies ◽  
Cytotoxicity Test ◽  
The Impact

The control of surface bioadhesive properties of the subcutaneous implants is essential for the development of biosensors and controlled drug release devices. Poly(alkyl ethylene phosphate)-based (co)polymers are structurally versatile, biocompatible and biodegradable, and may be regarded as an alternative to poly(ethylene glycol) (PEG) copolymers in the creation of antiadhesive materials. The present work reports the synthesis of block copolymers of ε-caprolactone (εCL) and 2-ethoxy-1,3,2-dioxaphospholane-2-oxide (ethyl ethylene phosphate, EtOEP) with different content of EtOEP fragments, preparation of polymer films, and the results of the study of the impact of EtOEP/εCL ratio on the hydrophilicity (contact angle of wetting), hydrolytic stability, cytotoxicity, protein and cell adhesion, and cell proliferation using umbilical cord multipotent stem cells. It was found that the increase of EtOEP/εCL ratio results in increase of hydrophilicity of the polymer films with lowering of the protein and cell adhesion. MTT cytotoxicity test showed no significant deviations in toxicity of poly(εCL) and poly(εCL)-b-poly(EtOEP)-based films. The influence of the length of poly(EtOEP)chain in block-copolymers on fibrotic reactions was analyzed using subcutaneous implantation experiments (Wistar line rats), the increase of the width of the fibrous capsule correlated with higher EtOEP/εCL ratio. However, the copolymer-based film with highest content of polyphosphate had been subjected to faster degradation with a formation of developed contact surface of poly(εCL). The rate of the degradation of polyphosphate in vivo was significantly higher than the rate of the degradation of polyphosphate in vitro, which only confirms an objective value of in vivo experiments in the development of polymer materials for biomedical applications.

Sulfated glyco-block copolymers with specific receptor and growth factor binding to support cell adhesion and proliferation

Biomaterials ◽  
2009 ◽  
Vol 30 (6) ◽  
pp. 1026-1035 ◽  
Author(s):  
Zeynep Oezyuerek ◽  
Katja Franke ◽  
Mirko Nitschke ◽  
Roland Schulze ◽  
Frank Simon ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Growth Factor ◽  
Block Copolymers ◽  
Specific Receptor ◽  
Factor Binding ◽  
Support Cell ◽  
Cell Adhesion And Proliferation

Fabrication of Electrically Bistable Organic Semiconducting/Ferroelectric Blend Films by Temperature Controlled Spin Coating

2015 ◽  
Vol 7 (11) ◽  
pp. 6325-6330 ◽  
Author(s):  
Jinghang Hu ◽  
Jianchi Zhang ◽  
Zongyuan Fu ◽  
Junhui Weng ◽  
Weibo Chen ◽  
...  
Keyword(s):  
Spin Coating ◽  
Blend Films ◽  
Temperature Controlled

scholarly journals Deposition of Transition Temperature Controlled Thermochromic NdxSm1-xNiO3 Films by Spin Coating

2017 ◽  
Vol 6 (2) ◽  
pp. 79
Author(s):  
Hidetoshi Miyazaki ◽  
Yusuke Maejima ◽  
Yuki Makinose
Keyword(s):  
Heat Treatment ◽  
Transition Temperature ◽  
Aqueous Solutions ◽  
Spin Coating ◽  
Oxygen Atmosphere ◽  
Transition Temperatures ◽  
Spin Coating Method ◽  
Coating Method ◽  
Thermochromic Properties ◽  
Temperature Controlled

The precursor samarium nickelate or samarium-neodimium nickelate films were fabricated by a spin coating method using Sm-Ni or Nd-Sm-Ni aqueous solutions, and SmNiO3 and Nd0.5Sm0.5NiO3 films were obtained by heat-treatment of the precursor films at 750 °C in oxygen atmosphere. The resulting SmNiO3 and Nd0.5Sm0.5NiO3 films showed an electrical transition with the transition temperatures of 124.0 and 32.5 °C, respectively. Both of the films showed optical thermochromic properties at the above mentioned transition temperatures.

“Click-Functional” Block Copolymers Provide Precise Surface Functionality via Spin Coating

Langmuir ◽  
2008 ◽  
Vol 24 (14) ◽  
pp. 7450-7456 ◽  
Author(s):  
Hernán R. Rengifo ◽  
Lu Chen ◽  
Cristian Grigoras ◽  
Jingyue Ju ◽  
Jeffrey T. Koberstein
Keyword(s):  
Block Copolymers ◽  
Spin Coating ◽  
Surface Functionality ◽  
Functional Block ◽  
Functional Block Copolymers

scholarly journals Synthesis of A-B-A tri-block copolymers containing poly(.BETA.-benzyl-L-aspartate) and their cell adhesion properties.

1985 ◽  
Vol 42 (11) ◽  
pp. 731-738 ◽  
Author(s):  
Kouhei KUGO ◽  
Takeshi UNO ◽  
Hitoshi YAMANO ◽  
Jun NISHINO ◽  
Hideo MASUDA
Keyword(s):  
Cell Adhesion ◽  
Block Copolymers ◽  
Adhesion Properties
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