N,O-Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils

2020 ◽  
Vol 56 (53) ◽  
pp. 7269-7272
Author(s):  
Yimin Chen ◽  
Chang Yuan ◽  
Tianxin Xie ◽  
Yuying Li ◽  
Bin Dai ◽  
...  
Keyword(s):  
Near Infrared ◽  
Β Amyloid ◽  
Infrared Probes ◽  
Tau Fibrils

In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was designed, prepared and evaluated as Aβ and Tau probes.

Novel D–A–D based near-infrared probes for the detection of β-amyloid and Tau fibrils in Alzheimer's disease

2018 ◽  
Vol 54 (63) ◽  
pp. 8717-8720 ◽  
Author(s):  
Yuying Li ◽  
Kan Wang ◽  
Kaixiang Zhou ◽  
Wentao Guo ◽  
Bin Dai ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Near Infrared ◽  
Β Amyloid ◽  
Infrared Probes ◽  
Tau Fibrils

Novel D–π–A–π–D probes were investigated for the detection of Aβ plaques and NFTs.

scholarly journals Imaging of β-amyloid plaques by near infrared fluorescent tracers: a new frontier for chemical neuroscience

2015 ◽  
Vol 44 (7) ◽  
pp. 1807-1819 ◽  
Author(s):  
Matteo Staderini ◽  
María Antonia Martín ◽  
Maria Laura Bolognesi ◽  
J. Carlos Menéndez
Keyword(s):  
Near Infrared ◽  
Amyloid Plaques ◽  
Fluorescent Tracers ◽  
Non Invasive ◽  
Nir Imaging ◽  
New Frontier ◽  
Invasive Method ◽  
Β Amyloid

Near infrared (NIR) imaging is a promising and non-invasive method to visualize amyloid plaquesin vivo.

A hemicyanine derivative for near-infrared imaging of β-amyloid plaques in Alzheimer's disease

2019 ◽  
Vol 179 ◽  
pp. 736-743 ◽  
Author(s):  
Hua-Li Yang ◽  
Si-Qiang Fang ◽  
Yan-Wei Tang ◽  
Cheng Wang ◽  
Heng Luo ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Near Infrared ◽  
Infrared Imaging ◽  
Amyloid Plaques ◽  
Near Infrared Imaging ◽  
Β Amyloid

scholarly journals Near-infrared probes based on fluorinated Si-rhodamine for live cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 10922-10927 ◽  
Author(s):  
Suxia Shen ◽  
Jingru Yu ◽  
Yaomin Lu ◽  
Shuchen Zhang ◽  
Xuegang Yi ◽  
...  
Keyword(s):  
Phenyl Ring ◽  
Live Cell Imaging ◽  
Near Infrared ◽  
Cell Imaging ◽  
Live Cell ◽  
Trifluoromethyl Group ◽  
High Brightness ◽  
Infrared Probes ◽  
Excellent Stability

Si-rhodamine probe with a trifluoromethyl group on the 2-position of the pendant phenyl ring retains high brightness and excellent stability in a harsh physiological environment.

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