Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media

2002 ◽  
Vol 29 (5) ◽  
pp. 803-809 ◽  
Author(s):  
Vasilis Ntziachristos ◽  
Ralph Weissleder
Keyword(s):  
Near Infrared ◽  
Turbid Media ◽  
Charge Coupled Device ◽  
Infrared Probes

N,O-Benzamide difluoroboron complexes as near-infrared probes for the detection of β-amyloid and tau fibrils

2020 ◽  
Vol 56 (53) ◽  
pp. 7269-7272
Author(s):  
Yimin Chen ◽  
Chang Yuan ◽  
Tianxin Xie ◽  
Yuying Li ◽  
Bin Dai ◽  
...  
Keyword(s):  
Near Infrared ◽  
Β Amyloid ◽  
Infrared Probes ◽  
Tau Fibrils

In this study, a series of organo difluoroboron probes with a BF2 benzamide moiety was designed, prepared and evaluated as Aβ and Tau probes.

scholarly journals Interferometric near-infrared spectroscopy directly quantifies optical field dynamics in turbid media

Optica ◽  
2016 ◽  
Vol 3 (12) ◽  
pp. 1471 ◽  
Author(s):  
Dawid Borycki ◽  
Oybek Kholiqov ◽  
Vivek J. Srinivasan
Keyword(s):  
Infrared Spectroscopy ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Optical Field ◽  
Turbid Media

Raman Signal Enhancement in Deep Spectroscopy of Turbid Media

2007 ◽  
Vol 61 (8) ◽  
pp. 845-854 ◽  
Author(s):  
P. Matousek
Keyword(s):  
Raman Spectroscopy ◽  
Laser Radiation ◽  
Laser Beam ◽  
Near Infrared ◽  
Optical Element ◽  
Disease Diagnosis ◽  
Pharmaceutical Products ◽  
Turbid Media ◽  
Raman Signal

A new, passive method for enhancing spontaneous Raman signals for the spectroscopic investigation of turbid media is presented. The main areas to benefit are transmission Raman and spatially offset Raman spectroscopy approaches for deep probing of turbid media. The enhancement, which is typically several fold, is achieved using a multilayer dielectric optical element, such as a bandpass filter, placed within the laser beam over the sample. This element prevents loss of the photons that re-emerge from the medium at the critical point where the laser beam enters the sample, the point where major photon loss occurs. This leads to a substantial increase of the coupling of laser radiation into the sample and consequently an enhanced laser photon–medium interaction process. The method utilizes the angular dependence of dielectric optical elements on impacting photon direction with its transmission spectral profile shifting to the blue with increase in the deviation of photons away from normal incidence. This feature enables it to act as a unidirectional mirror passing a semi-collimated laser beam through unhindered from one side, and at the other side, reflecting photons emerging from the sample at random directions back into it with no restrictions to the detected Raman signal. With substantial restrictions to the spectral range, the concept can also be applied to conventional backscattering Raman spectroscopy. The use of additional reflective elements around the sample to enhance the Raman signal further is also discussed. The increased signal strength yields higher signal quality, a feature important in many applications. Potential uses include sensitive noninvasive disease diagnosis in vivo, security screening, and quality control of pharmaceutical products. The concept is also applicable in an analogous manner to other types of analytical methods such as fluorescence or near-infrared (NIR) absorption spectroscopy of turbid media or it can be used to enhance the effectiveness of the coupling of laser radiation into tissue in applications such as photodynamic therapy for cancer treatment.

Discriminating forchlorfenuron-treated kiwifruits using a portable spectrometer and Vis/NIR diffuse transmittance spectroscopy technology

2017 ◽  
Vol 9 (28) ◽  
pp. 4207-4214 ◽  
Author(s):  
Dayang Liu ◽  
Qianqian Li ◽  
Weiqiang Li ◽  
Biao Yang ◽  
Wenchuan Guo
Keyword(s):  
Optical Fiber ◽  
Wavelength Range ◽  
Near Infrared ◽  
Low Cost ◽  
Fiber Probe ◽  
Charge Coupled Device ◽  
Optical Fiber Probe ◽  
Spectroscopy System

To explore the feasibility of low-cost miniaturized spectrometers in discriminating forchlorfenuron treated kiwifruits, a visible and near infrared (Vis/NIR) diffuse transmittance spectroscopy system was constructed by using a miniaturized charge coupled device (CCD) spectrometer in the wavelength range of 400–1100 nm and a self-developed optical fiber probe.

scholarly journals Near-infrared probes based on fluorinated Si-rhodamine for live cell imaging

RSC Advances ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 10922-10927 ◽  
Author(s):  
Suxia Shen ◽  
Jingru Yu ◽  
Yaomin Lu ◽  
Shuchen Zhang ◽  
Xuegang Yi ◽  
...  
Keyword(s):  
Phenyl Ring ◽  
Live Cell Imaging ◽  
Near Infrared ◽  
Cell Imaging ◽  
Live Cell ◽  
Trifluoromethyl Group ◽  
High Brightness ◽  
Infrared Probes ◽  
Excellent Stability

Si-rhodamine probe with a trifluoromethyl group on the 2-position of the pendant phenyl ring retains high brightness and excellent stability in a harsh physiological environment.

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