The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells

2021 ◽  
Author(s):  
Abdul Hadi Mehmood ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Wenhui Song ◽  
Yaru Sun ◽  
...  

An effective turn-on ER-targeting fluorescent probe ER-DTT was designed to image DTT of endoplasmic reticulum for the first time.

2019 ◽  
Vol 11 (29) ◽  
pp. 3736-3740 ◽  
Author(s):  
Cheng-Shi Jiang ◽  
Zhi-Qiang Cheng ◽  
Yong-Xi Ge ◽  
Jia-Li Song ◽  
Juan Zhang ◽  
...  

A new endoplasmic reticulum (ER)-targeting fluorescent probe (ER-G) was designed and applied for the detection of cellular GSH in the ER.


2020 ◽  
Vol 56 (47) ◽  
pp. 6344-6347 ◽  
Author(s):  
Yanyan Zhao ◽  
Hongyu Li ◽  
Ziyin Chai ◽  
Wen Shi ◽  
Xiaohua Li ◽  
...  

A new ER-targeting fluorescent probe for ˙OH is developed and applied to imaging ˙OH generation as well as lipid droplet formation in ER stress.


2020 ◽  
Vol 44 (42) ◽  
pp. 18389-18398
Author(s):  
Qiujuan Ma ◽  
Chunyan Wang ◽  
Guojiang Mao ◽  
Meiju Tian ◽  
Jingguo Sun ◽  
...  

A novel reticulum-targeting and ratiometric fluorescent probe for determining hypochlorous acid has been developed.


2020 ◽  
Vol 30 (6) ◽  
pp. 1357-1364
Author(s):  
Lei Zhou ◽  
Yunxia Li ◽  
Aiqin Zhou ◽  
Guanghui Zhang ◽  
Zhi-Qiang Cheng ◽  
...  

2018 ◽  
Vol 10 (47) ◽  
pp. 5702-5706 ◽  
Author(s):  
Nan Zhang ◽  
Baoli Dong ◽  
Xiuqi Kong ◽  
Wenhui Song ◽  
Weiying Lin

The pH changes of the endoplasmic reticulum (ER) are closely related to many diseases.


RSC Advances ◽  
2016 ◽  
Vol 6 (71) ◽  
pp. 66774-66778 ◽  
Author(s):  
Prithidipa Sahoo ◽  
Himadri Sekhar Sarkar ◽  
Sujoy Das ◽  
Kalipada Maiti ◽  
Md Raihan Uddin ◽  
...  

A new ‘turn-ON’ fluorescent probe, pyrene appended thymine acetamide (PTA), with high sensitivity and selectivity for the detection of uric acid (UA) was developed and first time imaging of uric acid in living cells in water was achieved.


2017 ◽  
Vol 5 (2) ◽  
pp. 024005 ◽  
Author(s):  
Yonghe Tang ◽  
Yanyan Ma ◽  
An Xu ◽  
Gaoping Xu ◽  
Weiying Lin

2019 ◽  
Vol 11 (35) ◽  
pp. 4450-4455 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  

As an important reactive oxygen species, hypochlorous acid (HClO) could irreversibly destroy Ca2+-ATPase to inhibit Ca2+ transport in the endoplasmic reticulum (ER), which may eventually lead to cell dysfunction and cell death.


2019 ◽  
Vol 43 (30) ◽  
pp. 12103-12108 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  

Cell polarity is one of the important parameters of the biological microenvironment, and controls the synthesis of functional proteins.


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