An endoplasmic reticulum-targeting and ratiometric fluorescent probe for hypochlorous acid in living cells based on a 1,8-naphthalimide derivative

2020 ◽  
Vol 44 (42) ◽  
pp. 18389-18398
Author(s):  
Qiujuan Ma ◽  
Chunyan Wang ◽  
Guojiang Mao ◽  
Meiju Tian ◽  
Jingguo Sun ◽  
...  

A novel reticulum-targeting and ratiometric fluorescent probe for determining hypochlorous acid has been developed.

2019 ◽  
Vol 11 (35) ◽  
pp. 4450-4455 ◽  
Author(s):  
Wenhui Song ◽  
Baoli Dong ◽  
Yaru Lu ◽  
Xiuqi Kong ◽  
Abdul Hadi Mehmood ◽  
...  

As an important reactive oxygen species, hypochlorous acid (HClO) could irreversibly destroy Ca2+-ATPase to inhibit Ca2+ transport in the endoplasmic reticulum (ER), which may eventually lead to cell dysfunction and cell death.


2017 ◽  
Vol 247 ◽  
pp. 736-741 ◽  
Author(s):  
Qiong Yuan ◽  
Zhi-Min Zhao ◽  
Yan-Ru Zhang ◽  
Le Su ◽  
Jun-Ying Miao ◽  
...  

2020 ◽  
Vol 92 (14) ◽  
pp. 9982-9988 ◽  
Author(s):  
Wei Shu ◽  
Shunping Zang ◽  
Chong Wang ◽  
Mengxu Gao ◽  
Jing Jing ◽  
...  

2018 ◽  
Vol 10 (47) ◽  
pp. 5702-5706 ◽  
Author(s):  
Nan Zhang ◽  
Baoli Dong ◽  
Xiuqi Kong ◽  
Wenhui Song ◽  
Weiying Lin

The pH changes of the endoplasmic reticulum (ER) are closely related to many diseases.


2019 ◽  
Vol 11 (29) ◽  
pp. 3736-3740 ◽  
Author(s):  
Cheng-Shi Jiang ◽  
Zhi-Qiang Cheng ◽  
Yong-Xi Ge ◽  
Jia-Li Song ◽  
Juan Zhang ◽  
...  

A new endoplasmic reticulum (ER)-targeting fluorescent probe (ER-G) was designed and applied for the detection of cellular GSH in the ER.


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