Genetically engineered haemoglobin wrapped covalently with human serum albumins as an artificial O2 carrier

2020 ◽  
Vol 8 (6) ◽  
pp. 1139-1145 ◽  
Author(s):  
Ryosuke Funaki ◽  
Wataru Okamoto ◽  
Chihiro Endo ◽  
Yoshitsugu Morita ◽  
Kiyohito Kihira ◽  
...  
Keyword(s):  
Blood Cell ◽  
Human Serum ◽  
Red Blood Cell ◽  
Genetically Engineered ◽  
Core Shell ◽  
Serum Albumins ◽  
Human Haemoglobin

Recombinant human haemoglobin expressed in Pichia yeast was wrapped covalently with recombinant human serum albumins, yielding a core–shell structured rHbA(X)–rHSA3 cluster as an entirely synthetic O2 carrier used for a red blood cell substitute.

scholarly journals Core–shell clusters of human haemoglobin A and human serum albumin: artificial O2-carriers having various O2-affinities

2015 ◽  
Vol 3 (30) ◽  
pp. 6157-6164 ◽  
Author(s):  
Takuya Kimura ◽  
Ryuichi Shinohara ◽  
Christoph Böttcher ◽  
Teruyuki Komatsu
Keyword(s):  
Human Serum Albumin ◽  
Blood Cell ◽  
Serum Albumin ◽  
Human Serum ◽  
Red Blood Cell ◽  
Core Shell ◽  
Human Haemoglobin ◽  
Artificial O2 Carriers

Core–shell clusters composed of human haemoglobin A and human serum albumin having various O2-affinities have been synthesized as potential O2-carriers designed as red blood cell substitutes.

Core–shell protein clusters comprising haemoglobin and recombinant feline serum albumin as an artificial O2carrier for cats

2018 ◽  
Vol 6 (16) ◽  
pp. 2417-2425 ◽  
Author(s):  
Kyoko Yokomaku ◽  
Motofusa Akiyama ◽  
Yoshitsugu Morita ◽  
Kiyohito Kihira ◽  
Teruyuki Komatsu
Keyword(s):  
Blood Cell ◽  
Serum Albumin ◽  
Red Blood Cell ◽  
Core Shell ◽  
Serum Albumins ◽  
Shell Protein ◽  
Protein Clusters

Dual-protein clusters comprising haemoglobin and recombinant feline serum albumins as a red blood cell substitute for exclusive use in cats.

scholarly journals Biomimetic Nanotherapies: Red Blood Cell Based Core–Shell Structured Nanocomplexes for Atherosclerosis Management

2019 ◽  
Vol 6 (12) ◽  
pp. 1900172 ◽  
Author(s):  
Yi Wang ◽  
Kang Zhang ◽  
Xian Qin ◽  
Tianhan Li ◽  
Juhui Qiu ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Core Shell

Dual sensitive and rapid detection of glycated human serum albumin using a versatile lead/graphene nanocomposite probe as a fluorescence-electrochemical aptasensor

The Analyst ◽  
2021 ◽  
Author(s):  
Thitirat Putnin ◽  
Wassa Waiwinya ◽  
Dechnarong Pimalai ◽  
Wireeya Chawjiraphan ◽  
Nuankanya Sathirapongsasuti ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Human Serum Albumin ◽  
Blood Cell ◽  
Serum Albumin ◽  
Human Serum ◽  
Red Blood Cell ◽  
Rapid Detection ◽  
Electrochemical Aptasensor ◽  
Graphene Nanocomposite

Monitoring of glycated human serum albumin (GHSA) as a glycemic marker for screening and monitoring of diabetes mellitus is widely practiced for patients with conditions that affect red blood cell....

Human serum albumin incorporating synthetic heme: Red blood cell substitute without hypertension by nitric oxide scavenging

2003 ◽  
Vol 64A (2) ◽  
pp. 257-261 ◽  
Author(s):  
Eishun Tsuchida ◽  
Teruyuki Komatsu ◽  
Yasuko Matsukawa ◽  
Akito Nakagawa ◽  
Hiromi Sakai ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Human Serum Albumin ◽  
Blood Cell ◽  
Serum Albumin ◽  
Human Serum ◽  
Red Blood Cell

Variation in porcine red blood cell α-galactosyl expression and agglutination by human serum

1998 ◽  
Vol 30 (5) ◽  
pp. 2468 ◽  
Author(s):  
L MacLaren ◽  
T.D.G Lee ◽  
D Anderson ◽  
M Nass ◽  
V.C McAlister
Keyword(s):  
Blood Cell ◽  
Human Serum ◽  
Red Blood Cell
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