scholarly journals Biomimetic Nanotherapies: Red Blood Cell Based Core–Shell Structured Nanocomplexes for Atherosclerosis Management

2019 ◽  
Vol 6 (12) ◽  
pp. 1900172 ◽  
Author(s):  
Yi Wang ◽  
Kang Zhang ◽  
Xian Qin ◽  
Tianhan Li ◽  
Juhui Qiu ◽  
...  
Keyword(s):  
2015 ◽  
Vol 3 (30) ◽  
pp. 6157-6164 ◽  
Author(s):  
Takuya Kimura ◽  
Ryuichi Shinohara ◽  
Christoph Böttcher ◽  
Teruyuki Komatsu

Core–shell clusters composed of human haemoglobin A and human serum albumin having various O2-affinities have been synthesized as potential O2-carriers designed as red blood cell substitutes.


2018 ◽  
Vol 6 (16) ◽  
pp. 2417-2425 ◽  
Author(s):  
Kyoko Yokomaku ◽  
Motofusa Akiyama ◽  
Yoshitsugu Morita ◽  
Kiyohito Kihira ◽  
Teruyuki Komatsu

Dual-protein clusters comprising haemoglobin and recombinant feline serum albumins as a red blood cell substitute for exclusive use in cats.


2020 ◽  
Vol 8 (6) ◽  
pp. 1139-1145 ◽  
Author(s):  
Ryosuke Funaki ◽  
Wataru Okamoto ◽  
Chihiro Endo ◽  
Yoshitsugu Morita ◽  
Kiyohito Kihira ◽  
...  

Recombinant human haemoglobin expressed in Pichia yeast was wrapped covalently with recombinant human serum albumins, yielding a core–shell structured rHbA(X)–rHSA3 cluster as an entirely synthetic O2 carrier used for a red blood cell substitute.


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