Facile construction of boranil complexes with aggregation-induced emission characteristics and their specific lipid droplet imaging applications

2019 ◽  
Vol 55 (58) ◽  
pp. 8494-8497 ◽  
Author(s):  
Na Zhao ◽  
Chengcheng Ma ◽  
Weiyao Yang ◽  
Wei Yin ◽  
Jiahui Wei ◽  
...  
Keyword(s):  
Lipid Droplet ◽  
Lipid Droplets ◽  
Living Cells ◽  
Emission Characteristics ◽  
Aggregation Induced Emission ◽  
Specific Lipid

A series of boranil complexes with aggregation-induced emission effects were facilely constructed, which can be utilized to image lipid droplets in living cells and yolk lipids in zebrafish.

Rational construction of AIEgens with wide color tunability and their specific lipid droplet imaging applications

2020 ◽  
Vol 8 (41) ◽  
pp. 9533-9543
Author(s):  
Fei Zhang ◽  
Zhe Li ◽  
Yaoming Liu ◽  
Binsheng Yang ◽  
Hui Qiao ◽  
...  
Keyword(s):  
Lipid Droplet ◽  
Rapid Development ◽  
Light Emitting ◽  
Aggregation Induced Emission ◽  
Organic Light ◽  
Color Tunability ◽  
Rational Construction ◽  
Specific Lipid

Organic light-emitting materials with aggregation-induced emission (AIE) character have experienced a rapid development in imaging, visualization and sensing.

scholarly journals Biogenesis of the multifunctional lipid droplet: Lipids, proteins, and sites

2014 ◽  
Vol 204 (5) ◽  
pp. 635-646 ◽  
Author(s):  
Albert Pol ◽  
Steven P. Gross ◽  
Robert G. Parton
Keyword(s):  
Energy Metabolism ◽  
Lipid Droplet ◽  
Cell Biology ◽  
Lipid Droplets ◽  
Recent Progress ◽  
Human Diseases ◽  
Membrane Synthesis ◽  
Specific Lipid

Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and production of essential lipid-derived molecules. Interest in the organelle’s cell biology has exponentially increased over the last decade due to the link between LDs and prevalent human diseases and the discovery of new and unexpected functions of LDs. As a result, there has been significant recent progress toward understanding where and how LDs are formed, and the specific lipid pathways that coordinate LD biogenesis.

The unusual aggregation-induced emission of coplanar organoboron isomers and their lipid droplet-specific applications

2018 ◽  
Vol 2 (8) ◽  
pp. 1498-1507 ◽  
Author(s):  
Jen-Shyang Ni ◽  
Haixiang Liu ◽  
Junkai Liu ◽  
Meijuan Jiang ◽  
Zheng Zhao ◽  
...  
Keyword(s):  
Excited State ◽  
Double Bond ◽  
Lipid Droplet ◽  
Lipid Droplets ◽  
Aggregation Induced Emission ◽  
Bond Reorganization

Organoboron isomers are not only rare coplanar AIEgens stemmed from excited-state double-bond reorganization, but also specifically target lipid droplets.

A highly selective AIE fluorogen for lipid droplet imaging in live cells and green algae

2014 ◽  
Vol 2 (14) ◽  
pp. 2013-2019 ◽  
Author(s):  
Erjing Wang ◽  
Engui Zhao ◽  
Yuning Hong ◽  
Jacky W. Y. Lam ◽  
Ben Zhong Tang
Keyword(s):  
Green Algae ◽  
Lipid Droplet ◽  
Lipid Droplets ◽  
High Selectivity ◽  
High Specificity ◽  
Live Cells ◽  
Aggregation Induced Emission ◽  
Low Cytotoxicity ◽  
Excellent Photostability

An aggregation-induced emission fluorogen, TPE-AmAl, is reported to selectively image lipid droplets in live cells and green algae with high selectivity, high specificity, excellent photostability and low cytotoxicity.

scholarly journals Two-photon AIE bio-probe with large Stokes shift for specific imaging of lipid droplets

2017 ◽  
Vol 8 (8) ◽  
pp. 5440-5446 ◽  
Author(s):  
Meijuan Jiang ◽  
Xinggui Gu ◽  
Jacky W. Y. Lam ◽  
Yilin Zhang ◽  
Ryan T. K. Kwok ◽  
...  
Keyword(s):  
Lipid Droplet ◽  
Lipid Droplets ◽  
Stokes Shift ◽  
Large Stokes Shift ◽  
Two Photon ◽  
Photon Excitation ◽  
Specific Lipid ◽  
Two Photon Excitation ◽  
In Cells

A novel AIEgen with prominent two-photon excitation was rationally developed for specific lipid-droplet imaging in cells and tissues.

scholarly journals A near-infrared AIEgen for specific imaging of lipid droplets

2016 ◽  
Vol 52 (35) ◽  
pp. 5957-5960 ◽  
Author(s):  
Miaomiao Kang ◽  
Xinggui Gu ◽  
Ryan T. K. Kwok ◽  
Chris W. T. Leung ◽  
Jacky W. Y. Lam ◽  
...  
Keyword(s):  
Lipid Droplet ◽  
Lipid Droplets ◽  
Near Infrared ◽  
High Brightness ◽  
Good Biocompatibility ◽  
Specific Lipid

A new near-infrared AIE luminogen is developed for specific lipid droplet imaging with high brightness, good biocompatibility and superior photostability.

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