scholarly journals Correction: Bacterial detection and identification from human synovial fluids on an integrated microfluidic system

The Analyst ◽  
2019 ◽  
Vol 144 (19) ◽  
pp. 5898-5898
Author(s):  
Ting-Hang Liu ◽  
Shu-Shen Cheng ◽  
Huey-Ling You ◽  
Mel S. Lee ◽  
Gwo-Bin Lee

Correction for ‘Bacterial detection and identification from human synovial fluids on an integrated microfluidic system’ by Ting-Hang Liu et al., Analyst, 2019, 144, 1210–1222.

The Analyst ◽  
2019 ◽  
Vol 144 (4) ◽  
pp. 1210-1222 ◽  
Author(s):  
Ting-Hang Liu ◽  
Shu-Shen Cheng ◽  
Huey-Ling You ◽  
Mel S. Lee ◽  
Gwo-Bin Lee

An integrated microfluidic system was developed for detecting and identifying four bacteria in human joint fluid with the limit of detection as low as 100 colony forming units (CFUs) per milliliter (or 20 CFUs per reaction).


Lab on a Chip ◽  
2021 ◽  
Author(s):  
Wenxiu Zhao ◽  
Haibo Yu ◽  
Yangdong Wen ◽  
Hao Luo ◽  
Boliang Jia ◽  
...  

Counting the number of red blood cells (RBCs) in blood samples is a common clinical diagnostic procedure, but conventional methods are unable to provide the size and other physical properties...


The Analyst ◽  
2015 ◽  
Vol 140 (23) ◽  
pp. 7896-7901 ◽  
Author(s):  
Yanlong Xing ◽  
Andreas Wyss ◽  
Norbert Esser ◽  
Petra S. Dittrich

Label-free biosensors based on in situ formed and functionalized TTF–Au wires were developed using an integrated microfluidic system.


Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3238 ◽  
Author(s):  
Fenja Knoepp ◽  
Joel Wahl ◽  
Anders Andersson ◽  
Johan Borg ◽  
Norbert Weissmann ◽  
...  

Acute hypoxia changes the redox-state of pulmonary arterial smooth muscle cells (PASMCs). This might influence the activity of redox-sensitive voltage-gated K+-channels (Kv-channels) whose inhibition initiates hypoxic pulmonary vasoconstriction (HPV). However, the molecular mechanism of how hypoxia—or the subsequent change in the cellular redox-state—inhibits Kv-channels remains elusive. For this purpose, a new multifunctional gas-tight microfluidic system was developed enabling simultaneous single-cell Raman spectroscopic studies (to sense the redox-state under normoxic/hypoxic conditions) and patch-clamp experiments (to study the Kv-channel activity). The performance of the system was tested by optically recording the O2-content and taking Raman spectra on murine PASMCs under normoxic/hypoxic conditions or in the presence of H2O2. Oxygen sensing showed that hypoxic levels in the gas-tight microfluidic system were achieved faster, more stable and significantly lower compared to a conventional open system (1.6 ± 0.2%, respectively 6.7 ± 0.7%, n = 6, p < 0.001). Raman spectra revealed that the redistribution of biomarkers (cytochromes, FeS, myoglobin and NADH) under hypoxic/normoxic conditions were improved in the gas-tight microfluidic system (p-values from 0.00% to 16.30%) compared to the open system (p-value from 0.01% to 98.42%). In conclusion, the new redox sensor holds promise for future experiments that may elucidate the role of Kv-channels during HPV.


2009 ◽  
Vol 407 (12) ◽  
pp. 3641-3651 ◽  
Author(s):  
Pedro Albuquerque ◽  
Marta V. Mendes ◽  
Catarina L. Santos ◽  
Pedro Moradas-Ferreira ◽  
Fernando Tavares

Lab on a Chip ◽  
2018 ◽  
Vol 18 (11) ◽  
pp. 1633-1640 ◽  
Author(s):  
Jia-Han Wu ◽  
Chih-Hung Wang ◽  
Yu-Dong Ma ◽  
Gwo-Bin Lee

A new, nitrocellulose-based microfluidic system featuring Acinetobacter baumannii (AB)-specific aptamers capable of automating the bacterial detection process was reported.


Lab on a Chip ◽  
2020 ◽  
Vol 20 (9) ◽  
pp. 1612-1620 ◽  
Author(s):  
Baris R. Mutlu ◽  
Taronish Dubash ◽  
Claudius Dietsche ◽  
Avanish Mishra ◽  
Arzu Ozbey ◽  
...  

Cell–cell adhesion strength of freely suspended cell clusters can be measured using an oscillatory inertial microfluidic system.


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