Polypyrrole-coated UCNPs@mSiO2@ZnO nanocomposite for combined photodynamic and photothermal therapy

2018 ◽  
Vol 6 (48) ◽  
pp. 8148-8162 ◽  
Author(s):  
Qi Cai ◽  
Jiating Xu ◽  
Dan Yang ◽  
Yunlu Dai ◽  
Guixin Yang ◽  
...  

Under 980 nm light irradiation, polypyrrole-coated UCNPs@mSiO2@ZnO nanocomposites can convert NIR light to achieve both photodynamic therapy (PDT) and photothermal therapy (PTT).

2018 ◽  
Vol 54 (100) ◽  
pp. 14108-14111 ◽  
Author(s):  
Kangqiang Qiu ◽  
Jinquan Wang ◽  
Thomas W. Rees ◽  
Liangnian Ji ◽  
Qianling Zhang ◽  
...  

A mitochondria-targeting photothermogenic nanozyme was used to increase localized temperature and accelerate the catalysis of H2O2 to ˙OH under NIR light irradiation for mild photothermal therapy.


2012 ◽  
Vol 16 (07n08) ◽  
pp. 802-808 ◽  
Author(s):  
J. Wang ◽  
H. Yan Tang ◽  
W. Li Yang ◽  
J. Yao Chen

The sulfonated aluminum phthalocyanines (AlPcSs), popularly used photosensitizers, were linked on the surfaces of gold nanorods (AuNRs) by the electrostatic binding to form AlPcS–AuNRs conjugates, in order to improve the photo-therapy efficiency of cancer cells by combining the photodynamic therapy (PDT) of AlPcSs and the photothermal therapy (PTT) of AuNRs . The AlPcS's fluorescence is two-fold enhanced when they adhered on the surfaces of AuNRs probably due to the surface Plasmon coupling, which would facilitate the AlPcS detection. The fluorescence images show that AuNRs can carry loaded AlPcSs to penetrate into human nasopharyngeal carcinoma cells with a fast speed, achieving the effective intracellular delivery of AlPcSs . The PTT effect of cellular AuNRs alone under the white light irradiation of 50 minutes decreased the cell viability to 77%, and the PDT effect of cellular AlPcS–AuNRs with filtered red light (670–710 nm) irradiation of 50 min lowered the cell viability to 79%. However, with the same white light irradiation of 50 min, the AlPcS–AuNRs destroyed most cells leaving the cell viability to 28%, reflecting a typical synergistic effect on cell killing. These results suggest that the combination of PTT and PDT with AlPcS–AuNRs is a promising strategy for improving the phototherapy of cancers.


2019 ◽  
Vol 7 (11) ◽  
pp. 4769-4781 ◽  
Author(s):  
Mingdi Sun ◽  
Dan Yang ◽  
Chen Wang ◽  
Huiting Bi ◽  
Yuan Zhou ◽  
...  

AgBiS2 nanodots as an NIR light-excited photosensitizer produce a PDT effect, which is reported for the first time.


Nanoscale ◽  
2019 ◽  
Vol 11 (39) ◽  
pp. 18183-18190 ◽  
Author(s):  
Haiyan Liang ◽  
Hongjuan Xi ◽  
Shaoqiong Liu ◽  
Xuemei Zhang ◽  
Haiqing Liu

Noble-metal like photoelectrocatalytic hydrogen evolution and efficient anticancer photothermal therapy were accomplished by simply tuning the oxygen vacancy of WO3 nanosheets under Vis-NIR light irradiation.


2019 ◽  
Vol 7 (11) ◽  
pp. 1867-1874 ◽  
Author(s):  
Shu-Wen Shi ◽  
Yan-Hui Li ◽  
Qian-Ling Zhang ◽  
Shi-Ping Yang ◽  
Jin-Gang Liu

A multifunctional nanoplatform exhibits selective intracellular co-delivery of Pt(ii) and NO under 808 nm light irradiation, accompanied by photothermal therapy.


2021 ◽  
Vol 9 (1) ◽  
pp. 101-111
Author(s):  
Peipei Jia ◽  
Hongjiao Ji ◽  
Shikai Liu ◽  
Rui Zhang ◽  
Fei He ◽  
...  

A novel Au–Bi bimetallic nanoplatform has been developed for enhanced photodynamic and photothermal therapy.


Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...


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