A mitochondria-targeting photothermogenic nanozyme for MRI-guided mild photothermal therapy

2018 ◽  
Vol 54 (100) ◽  
pp. 14108-14111 ◽  
Author(s):  
Kangqiang Qiu ◽  
Jinquan Wang ◽  
Thomas W. Rees ◽  
Liangnian Ji ◽  
Qianling Zhang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Light Irradiation ◽  
Nir Light ◽  
Mri Guided ◽  
Mitochondria Targeting

A mitochondria-targeting photothermogenic nanozyme was used to increase localized temperature and accelerate the catalysis of H2O2 to ˙OH under NIR light irradiation for mild photothermal therapy.

Polypyrrole-coated UCNPs@mSiO2@ZnO nanocomposite for combined photodynamic and photothermal therapy

2018 ◽  
Vol 6 (48) ◽  
pp. 8148-8162 ◽  
Author(s):  
Qi Cai ◽  
Jiating Xu ◽  
Dan Yang ◽  
Yunlu Dai ◽  
Guixin Yang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Photothermal Therapy ◽  
Light Irradiation ◽  
Nir Light

Under 980 nm light irradiation, polypyrrole-coated UCNPs@mSiO2@ZnO nanocomposites can convert NIR light to achieve both photodynamic therapy (PDT) and photothermal therapy (PTT).

Modulation of oxygen vacancy in tungsten oxide nanosheets for Vis-NIR light-enhanced electrocatalytic hydrogen production and anticancer photothermal therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (39) ◽  
pp. 18183-18190 ◽  
Author(s):  
Haiyan Liang ◽  
Hongjuan Xi ◽  
Shaoqiong Liu ◽  
Xuemei Zhang ◽  
Haiqing Liu
Keyword(s):  
Hydrogen Production ◽  
Oxygen Vacancy ◽  
Tungsten Oxide ◽  
Hydrogen Evolution ◽  
Noble Metal ◽  
Photothermal Therapy ◽  
Light Irradiation ◽  
Nir Light

Noble-metal like photoelectrocatalytic hydrogen evolution and efficient anticancer photothermal therapy were accomplished by simply tuning the oxygen vacancy of WO3 nanosheets under Vis-NIR light irradiation.

Targeted and NIR light-controlled delivery of nitric oxide combined with a platinum(iv) prodrug for enhanced anticancer therapy

2019 ◽  
Vol 7 (11) ◽  
pp. 1867-1874 ◽  
Author(s):  
Shu-Wen Shi ◽  
Yan-Hui Li ◽  
Qian-Ling Zhang ◽  
Shi-Ping Yang ◽  
Jin-Gang Liu
Keyword(s):  
Nitric Oxide ◽  
Photothermal Therapy ◽  
Anticancer Therapy ◽  
Controlled Delivery ◽  
Light Irradiation ◽  
Nir Light

A multifunctional nanoplatform exhibits selective intracellular co-delivery of Pt(ii) and NO under 808 nm light irradiation, accompanied by photothermal therapy.

Bi19S27I3 nanorods: a new candidate for photothermal therapy in the first and second biological near-infrared windows

Nanoscale ◽  
2021 ◽  
Author(s):  
Jinsong Xiong ◽  
Qinghuan Bian ◽  
Shuijin Lei ◽  
Yatian Deng ◽  
Kehan Zhao ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Research Interest ◽  
The Past ◽  
Nir Light ◽  
Considerable Research ◽  
Key Factor

Near-infrared (NIR) light induced photothermal cancer therapy using nanomaterials as photothermal agents has attracted considerable research interest over the past few years. As the key factor in the photothermal therapy...

scholarly journals Near-Infrared-Triggered Upconverting Nanoparticles for Biomedicine Applications

Biomedicines ◽  
2021 ◽  
Vol 9 (7) ◽  
pp. 756
Author(s):  
Manoj Kumar Mahata ◽  
Ranjit De ◽  
Kang Taek Lee
Keyword(s):  
Drug Delivery ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Cutting Edge ◽  
Clinical Translation ◽  
Basic Knowledge ◽  
Nanotechnology Research ◽  
Nir Light

Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine applications. Advances in the techniques for polymer, dye, and bio-molecule conjugation on the surface of the nanoparticles has further expanded their dynamic opportunities for optogenetics, oncotherapy and bioimaging. In this account, considering the primary benefits such as the absence of photobleaching, photoblinking, and autofluorescence of UCNPs not only facilitate the construction of accurate, sensitive and multifunctional nanoprobes, but also improve therapeutic and diagnostic results. We introduce, with the basic knowledge of upconversion, unique properties of UCNPs and the mechanisms involved in photon upconversion and discuss how UCNPs can be implemented in biological practices. In this focused review, we categorize the applications of UCNP-based various strategies into the following domains: neuromodulation, immunotherapy, drug delivery, photodynamic and photothermal therapy, bioimaging and biosensing. Herein, we also discuss the current emerging bioapplications with cutting edge nano-/biointerfacing of UCNPs. Finally, this review provides concluding remarks on future opportunities and challenges on clinical translation of UCNPs-based nanotechnology research.

scholarly journals Photothermal Therapy Using Gold Nanorods and Near-Infrared Light in a Murine Melanoma Model Increases Survival and Decreases Tumor Volume

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mary K. Popp ◽  
Imane Oubou ◽  
Colin Shepherd ◽  
Zachary Nager ◽  
Courtney Anderson ◽  
...  
Keyword(s):  
Light Source ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Volume ◽  
Infrared Light ◽  
Led Light ◽  
Murine Melanoma ◽  
Nir Light ◽  
Melanoma Model

Photothermal therapy (PTT) treatments have shown strong potential in treating tumors through their ability to target destructive heat preferentially to tumor regions. In this paper we demonstrate that PTT in a murine melanoma model using gold nanorods (GNRs) and near-infrared (NIR) light decreases tumor volume and increases animal survival to an extent that is comparable to the current generation of melanoma drugs. GNRs, in particular, have shown a strong ability to reach ablative temperatures quickly in tumors when exposed to NIR light. The current research tests the efficacy of GNRs PTT in a difficult and fast growing murine melanoma model using a NIR light-emitting diode (LED) light source. LED light sources in the NIR spectrum could provide a safer and more practical approach to photothermal therapy than lasers. We also show that the LED light source can effectively and quickly heatin vitroandin vivomodels to ablative temperatures when combined with GNRs. We anticipate that this approach could have significant implications for human cancer therapy.

CORMs loaded nanoplatform for the single NIR light-activated bioimaging, gas therapy, and photothermal therapy in vitro

2021 ◽  
Author(s):  
Shihao Pei ◽  
Jia-Bei Li ◽  
Zhuo Wang ◽  
Yao Xie ◽  
Jiabo Chen ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Cancer Treatment ◽  
Mitochondrial Dysfunction ◽  
Cancer Cells ◽  
Photothermal Therapy ◽  
Nir Light ◽  
Potential Alternative

Carbon monoxide (CO) can cause mitochondrial dysfunction, inducing apoptosis of cancer cells which sheds light on a potential alternative for cancer treatment. However, the existing CO-based compounds are inherently limited...

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