Hypoxia- and singlet oxygen-responsive chemo-photodynamic Micelles featured with glutathione depletion and aldehyde production

2019 ◽  
Vol 7 (1) ◽  
pp. 429-441 ◽  
Author(s):  
Jian Deng ◽  
Fang Liu ◽  
Lina Wang ◽  
Yang An ◽  
Min Gao ◽  
...  
Keyword(s):  
Drug Release ◽  
Singlet Oxygen ◽  
Glutathione Depletion ◽  
Efficient Approach ◽  
On Demand ◽  
Triggered Drug Release ◽  
Drug Liberation

Triggered drug release from anti-tumor nanomedicine is an efficient approach to address the dilemma of systemic nanocarrier stability and on-demand drug liberation in tumor sites.

scholarly journals Injectable nanoengineered stimuli-responsive hydrogels for on-demand and localized therapeutic delivery

Nanoscale ◽  
2017 ◽  
Vol 9 (40) ◽  
pp. 15379-15389 ◽  
Author(s):  
Nima A. Jalili ◽  
Manish K. Jaiswal ◽  
Charles W. Peak ◽  
Lauren M. Cross ◽  
Akhilesh K. Gaharwar
Keyword(s):  
Drug Release ◽  
Stimuli Responsive ◽  
Nanocomposite Hydrogels ◽  
Therapeutic Delivery ◽  
On Demand ◽  
Triggered Drug Release ◽  
Responsive Hydrogels

Injectable nanocomposite hydrogels for temperature triggered drug release.

Comb-like poly(l-cysteine) derivatives with different side groups: synthesis via photochemistry and click chemistry, multi-responsive nanostructures, triggered drug release and cytotoxicity

2015 ◽  
Vol 6 (38) ◽  
pp. 6857-6869 ◽  
Author(s):  
Xingjie Wu ◽  
Linzhu Zhou ◽  
Yue Su ◽  
Chang-Ming Dong
Keyword(s):  
Cancer Therapy ◽  
Drug Release ◽  
Click Chemistry ◽  
On Demand ◽  
Triggered Drug Release ◽  
Ene Addition

A series of comb-like graft polypeptides having different side groups and tunable grafting ratios were prepared by sequential photocleavage reactions and Michael-type thiol–ene addition, which provides a promising platform for on-demand nanomedicine and cancer therapy.

ATP triggered drug release and DNA co-delivery systems based on ATP responsive aptamers and polyethylenimine complexes

2016 ◽  
Vol 4 (21) ◽  
pp. 3832-3841 ◽  
Author(s):  
Guan-Hai Wang ◽  
Guo-Liang Huang ◽  
Yi Zhao ◽  
Xing-Xiang Pu ◽  
Tong Li ◽  
...  
Keyword(s):  
Drug Release ◽  
Anticancer Drug ◽  
Delivery Systems ◽  
On Demand ◽  
Triggered Drug Release

An ATP-responsive nanocarrier based on PEI and aptamers complexes was designed for anticancer drug and DNA co-delivery. The nanocarrier displayed on-demand drug release and effective gene capability.

Near-Infrared Light-Responsive Nanogels with Diselenide-Cross-Linkers for On-Demand Degradation and Triggered Drug Release

2015 ◽  
Vol 32 (5) ◽  
pp. 547-551 ◽  
Author(s):  
Yefei Tian ◽  
Jin Zheng ◽  
Xiaoling Tang ◽  
Qingguang Ren ◽  
Yajun Wang ◽  
...  
Keyword(s):  
Drug Release ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
On Demand ◽  
Triggered Drug Release

scholarly journals In vivo visible light-triggered drug release from an implanted depot

2015 ◽  
Vol 6 (1) ◽  
pp. 335-341 ◽  
Author(s):  
Carl-Johan Carling ◽  
Mathieu L. Viger ◽  
Viet Anh Nguyen Huu ◽  
Arnold V. Garcia ◽  
Adah Almutairi
Keyword(s):  
Drug Release ◽  
Visible Light ◽  
Degradable Polymer ◽  
On Demand ◽  
Triggered Drug Release

A visible light-degradable polymer allows on-demand in vivo photorelease of encapsulated dexamethasone from a subcutaneously implanted particle depot.

NIR-responsive polypeptide copolymer upconversion composite nanoparticles for triggered drug release and enhanced cytotoxicity

2015 ◽  
Vol 6 (21) ◽  
pp. 4030-4039 ◽  
Author(s):  
Gang Liu ◽  
Na Liu ◽  
Linzhu Zhou ◽  
Yue Su ◽  
Chang-Ming Dong
Keyword(s):  
Drug Delivery ◽  
Cancer Therapy ◽  
Drug Release ◽  
Near Infrared ◽  
Composite Nanoparticles ◽  
Infrared Light ◽  
Near Infrared Light ◽  
On Demand ◽  
Triggered Drug Release

Near infrared light-responsive polypeptide copolymer upconversion composite nanoparticles exhibited controllable drug release and triggered cytotoxicity useful for on-demand drug delivery and cancer therapy.

Shell cross-linked polyethylenimine-modified micelles for temperature-triggered drug release and gene delivery

RSC Advances ◽  
2014 ◽  
Vol 4 (101) ◽  
pp. 57702-57708 ◽  
Author(s):  
Su-Yeon Lee ◽  
Seong-Jun Choi ◽  
Seog-Jin Seo ◽  
Hae-Won Kim
Keyword(s):  
Gene Delivery ◽  
Drug Release ◽  
On Demand ◽  
Therapeutic Molecules ◽  
Triggered Drug Release

Stimuli-responsiveness is an important characteristic of nanocarriers that can deliver therapeutic molecules in a controlled and on-demand manner.

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