Highly efficient synthesis of β-nitrate ester carboxamides through the ring-opening of 2-oxazolines

2017 ◽  
Vol 19 (24) ◽  
pp. 5789-5793 ◽  
Author(s):  
Kai Qiao ◽  
Xin Yuan ◽  
Li Wan ◽  
Ming-Wei Zheng ◽  
Dong Zhang ◽  
...  
Keyword(s):  
Ring Opening ◽  
Efficient Synthesis ◽  
Nitrate Ester ◽  
Highly Efficient ◽  
Novel Method

A novel method for the synthesis of β-nitrate ester carboxamides using non-corrosivetert-butyl nitrite (TBN) as the nitro source and easily available oxygen as the oxidant has been developed.

scholarly journals Highly efficient synthesis of C3-symmetric O-alkyl substituted triphenylenes and related Mannich derivatives

2018 ◽  
Vol 5 (16) ◽  
pp. 2458-2462 ◽  
Author(s):  
Giacomo Berton ◽  
Giuseppe Borsato ◽  
Roberta Zangrando ◽  
Andrea Gambaro ◽  
Fabrizio Fabris ◽  
...  
Keyword(s):  
Ring Opening ◽  
Efficient Synthesis ◽  
Highly Efficient ◽  
Selective Ring Opening

C3-Symmetric tris-benzyl-O-substituted hexahydroxytriphenylene (HHTP) was prepared through selective ring opening with DIBAL-H in 48% yield (38% from HHTP in a two-step synthesis).

One-pot NHC-assisted access to 2,3-dihydropyrimido[4,5-d]pyrimidin-4(1H)-ones

RSC Advances ◽  
2014 ◽  
Vol 4 (67) ◽  
pp. 35629-35634 ◽  
Author(s):  
Mingxing Liu ◽  
Jiarong Li ◽  
Shu Chen ◽  
Danfei Huang ◽  
Hongxin Chai ◽  
...  
Keyword(s):  
Reaction Synthesis ◽  
The Novel ◽  
Efficient Synthesis ◽  
One Pot ◽  
Highly Efficient ◽  
Novel Method

An efficient N-heterocyclic carbene-assisted one-pot reaction synthesis of 2,3-dihydropyrimido[4,5-d] pyrimidin-4(1H)-ones from 2-(ethoxymethylene)malononitrile, guanidines (or amidines) and ketones (or aldehyde) has been developed. The novel method provides a highly efficient synthesis of pyrimido[4,5-d]pyrimidinering from materials with no heterocyclic structures.

A highly efficient metal-free protocol for the synthesis of linear polydicyclopentadiene

2021 ◽  
Author(s):  
Xuejin Yang ◽  
Laura M. Murphy ◽  
Farihah M. Haque ◽  
Scott M. Grayson ◽  
Andrew J. Boydston
Keyword(s):  
Ring Opening ◽  
Efficient Synthesis ◽  
Ring Opening Metathesis Polymerization ◽  
Free Ring ◽  
Metathesis Polymerization ◽  
Metal Free ◽  
Highly Efficient

We have developed a highly efficient synthesis of linear polydicyclopentadiene (pDCPD) via photoredox mediated metal-free ring-opening metathesis polymerization (MF-ROMP) and investigated the Tg–Mn dependence of linear pDCPD.

scholarly journals Synthesis of enantiomerically pure N-(2,3-dihydroxypropyl)arylamides via oxidative esterification

2013 ◽  
Vol 9 ◽  
pp. 2129-2136 ◽  
Author(s):  
Akula Raghunadh ◽  
Satish S More ◽  
T Krishna Chaitanya ◽  
Yadla Sateesh Kumar ◽  
Suresh Babu Meruva ◽  
...  
Keyword(s):  
Ring Opening ◽  
Efficient Synthesis ◽  
Enantiomerically Pure ◽  
Step Process ◽  
Oxidative Esterification ◽  
Highly Efficient ◽  
Chiral Purity ◽  
High Yields ◽  
Nitrogen Heterocyclic

A highly efficient synthesis of enantiomerically pure (S) and (R)-isomers of N-(2,3-dihydroxypropyl)arylamides has been developed with good overall yields in a two step process. The key step involves the ring opening of the chiral epoxide with a nitrogen heterocyclic carbene (NHC) and further rearrangement to chiral N-(2,3-dihydroxypropyl)arylamides in high yields and enantioselectivity. During the reaction, no erosion in chiral purity was observed.

scholarly journals Application of aziridinium ring opening for preparation of optically active diamine and triamine analogues: highly efficient synthesis and evaluation of DTPA-based MRI contrast enhancement agents

RSC Advances ◽  
2015 ◽  
Vol 5 (115) ◽  
pp. 94571-94581 ◽  
Author(s):  
Xiang Sun ◽  
Yunwei Chen ◽  
Ningjie Wu ◽  
Chi Soo Kang ◽  
Hyun A. Song ◽  
...  
Keyword(s):  
Contrast Enhancement ◽  
Ring Opening ◽  
Optically Active ◽  
Efficient Synthesis ◽  
Mri Contrast ◽  
Diethylene Triamine ◽  
Highly Efficient ◽  
Diethylene Triamine Pentaacetic Acid ◽  
Nitrogen Nucleophiles ◽  
Aziridinium Ions

Ring opening of aziridinium ions with nitrogen nucleophiles was applied to highly efficient synthesis of optically active vicinal diamines and diethylene triamine pentaacetic acid (DTPA) analogues.

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