Nanoparticles in β-tricalcium phosphate substrate enhance modulation of structure and composition of an octacalcium phosphate grown layer

CrystEngComm ◽  
2017 ◽  
Vol 19 (44) ◽  
pp. 6660-6672 ◽  
Author(s):  
Kazuo Onuma ◽  
Mayumi Iijima
Keyword(s):  
Tricalcium Phosphate ◽  
Octacalcium Phosphate ◽  
Grown Layer ◽  
Structural Modulation

Nanoparticles in the β-TCP substrate enhance structural modulation of an OCP grown layer.

Setting Properties of Brushite and Hydroxyapatite Compound Cements

2011 ◽  
Vol 222 ◽  
pp. 239-242 ◽  
Author(s):  
Zilgma Irbe ◽  
Linda Vecbiskena ◽  
Liga Berzina-Cimdina
Keyword(s):  
Long Range ◽  
Strong Evidence ◽  
Tricalcium Phosphate ◽  
Setting Time ◽  
Octacalcium Phosphate ◽  
Range Order ◽  
Long Range Order ◽  
Precursor Phase ◽  
Citrate Ions

In this work properties of potential brushite (CaHPO4•2H2O) and hydroxyapatite (Ca10(PO4)6(OH)2) compound cements are investigated. Calcium dihydrogenphosphate monohydrate (MCPM) and α-tricalcium phosphate (α-TCP) were the starting materials for investigated cements. Setting time is controlled by adding setting time retarder – citrate ions and initially unreactive filler - monetite (CaHPO4). Some compositions of obtained cements contain both brushite and hydroxyapatite. However a substantial amount of monetite was present even if it is not added as filler. There is a strong evidence of presence of octacalcium phosphate – a precursor phase for hydroxyapatite that lacks long range order.

Implanted octacalcium phosphate is more resorbable than ?-tricalcium phosphate and hydroxyapatite

2001 ◽  
Vol 59 (1) ◽  
pp. 29-34 ◽  
Author(s):  
S. Kamakura ◽  
Y. Sasano ◽  
T. Shimizu ◽  
K. Hatori ◽  
O. Suzuki ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Octacalcium Phosphate

Application of Sr-doped octacalcium phosphate as a novel Sr carrier in the α-tricalcium phosphate bone cement

2017 ◽  
Vol 43 (15) ◽  
pp. 12579-12587 ◽  
Author(s):  
Tao Yu ◽  
Shenghui Zeng ◽  
Xu Liu ◽  
Haishan Shi ◽  
Jiandong Ye ◽  
...  
Keyword(s):  
Bone Cement ◽  
Tricalcium Phosphate ◽  
Octacalcium Phosphate

scholarly journals In Vitro Properties of Manganese-Substituted Tricalcium Phosphate Coatings for Titanium Biomedical Implants Deposited by Arc Plasma

Materials ◽  
2020 ◽  
Vol 13 (19) ◽  
pp. 4411 ◽  
Author(s):  
Inna V. Fadeeva ◽  
Vasilii I. Kalita ◽  
Dmitry I. Komlev ◽  
Alexei A. Radiuk ◽  
Alexander S. Fomin ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Plasma Deposition ◽  
L929 Cell ◽  
Octacalcium Phosphate ◽  
Ceramic Coatings ◽  
Physiological Solution ◽  
Human Tooth ◽  
Arc Plasma ◽  
X Ray

Bioactive manganese (Mn)-doped ceramic coatings for intraosseous titanium (Ti) implants are developed. Arc plasma deposition procedure is used for coatings preparation. X-ray Diffraction, Scanning Electron Microscopy-Energy Dispersive X-ray Spectroscopy, and Electron Paramagnetic Resonance (EPR) methods are applied for coatings characterization. The coatings are homogeneous, composed of the main phase α-tricalcium phosphate (α-TCP) (about 67%) and the minor phase hydroxyapatite (about 33%), and the Mn content is 2.3 wt%. EPR spectroscopy demonstrates that the Mn ions are incorporated in the TCP structure and are present in the coating in Mn2+ and Mn3+ oxidation states, being aggregated in clusters. The wetting contact angle of the deposited coatings is suitable for cells’ adhesion and proliferation. In vitro soaking in physiological solution for 90 days leads to a drastic change in phase composition; the transformation into calcium carbonate and octacalcium phosphate takes place, and no more Mn is present. The absence of antibacterial activity against Escherichia coli, Enterococcus faecalis, and Pseudomonas aeruginosa bacteria strains is observed. A study of the metabolic activity of mouse fibroblasts of the NCTC L929 cell line on the coatings using the MTT (dye compound 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) test demonstrates that there is no toxic effect on the cell culture. Moreover, the coating material supports the adhesion and proliferation of the cells. A good adhesion, spreading, and proliferative activity of the human tooth postnatal dental pulp stem cells (DPSC) is demonstrated. The developed coatings are promising for implant application in orthopedics and dentistry.

Dicarboxylate-substituted octacalcium phosphates for hydrogel filling and resorbable ceramics fabrication

2020 ◽  
Vol 12 ◽  
pp. 27-41
Author(s):  
A. A. Tikhonov ◽  
◽  
E. S. Klimashina ◽  
P. V. Evdokimov ◽  
E. V. Kukueva ◽  
...  
Keyword(s):  
Polyethylene Glycol ◽  
3D Printing ◽  
Tricalcium Phosphate ◽  
Decomposition Product ◽  
Octacalcium Phosphate ◽  
Polyethylene Glycol Diacrylate ◽  
Glycol Diacrylate ◽  
Buffer Solutions ◽  
Hydrolysis Of ◽  
Printing Method

The main features of the synthesis of carboxylate-substituted analogs of octacalcium phosphate Ca8(HPO4)2(PO4)4·5H2O (OCP) by hydrolysis of brushite (CaHPO4·2H2O) and tricalcium phosphate α-Са3(РО4)2 (α-TCP) in buffer solutions based on the salts of succinic, adipic, and citric acids were summarized. The synthesis of succinate-substituted (Suc@OCP) and adipinate-substituted (Adi@OCP) OCPs gives the powders with Ca8(HPO4)2 – xАx(PO4)4·zH2O (А = Suc, Аdi) composition. Thermolysis of substituted OCPs results in a mixture of β-Са3(РО4)2 (β-TCP) and hydroxyapatite Са10(РО4)6(ОН)2 (HAp). Thermolysis features include the absence of an apatite-like decomposition product of pure OCP and higher decomposition temperatures compared to the pure OCP. Suc@OCP and Adi@OCP powders were used for the filling of hydrogels based on polyethylene glycol diacrylate (PEGDA) for the creation of a deformable composite implant by a stereolithographic 3D printing method, and fabrication of biphasic TCP/HAp ceramics.

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