scholarly journals Comparative study on the resorbability and dissolution behavior of octacalcium phosphate, β-tricalcium phosphate, and hydroxyapatite under physiological conditions

2016 ◽  
Vol 35 (2) ◽  
pp. 216-224 ◽  
Author(s):  
Susumu SAKAI ◽  
Takahisa ANADA ◽  
Kaori TSUCHIYA ◽  
Hajime YAMAZAKI ◽  
Henry C. MARGOLIS ◽  
...  
2020 ◽  
Vol 2 (12) ◽  
pp. 5760-5768
Author(s):  
Lukas Steinmetz ◽  
Christoph Geers ◽  
Sandor Balog ◽  
Mathias Bonmarin ◽  
Laura Rodriguez-Lorenzo ◽  
...  

The dissolution and aggregation behaviour of silver nanoparticles under physiological conditions and in biologically relevant environments is investigated by exploiting their plasmonic properties.


2017 ◽  
Vol 41 (12) ◽  
pp. 1399-1405
Author(s):  
Samanta Gasco ◽  
Amaya Rando ◽  
Pilar Zaragoza ◽  
Alberto García-Redondo ◽  
Ana Cristina Calvo ◽  
...  

2015 ◽  
Vol 354 (1) ◽  
pp. 258-264 ◽  
Author(s):  
Chotika Dararutana ◽  
Juthamas Ratanavaraporn ◽  
Sittisak Honsawek ◽  
Sorada Kanokpanont ◽  
Siriporn Damrongsakkul

2021 ◽  
Vol 22 (18) ◽  
pp. 9770
Author(s):  
Yukari Shiwaku ◽  
Ryo Hamai ◽  
Shinichi Sato ◽  
Susumu Sakai ◽  
Kaori Tsuchiya ◽  
...  

The microstructure of biomaterials influences the cellular and biological responses in the bone. Octacalcium phosphate (OCP) exhibits higher biodegradability and osteoconductivity than hydroxyapatite (HA) during the conversion process from OCP to HA. However, the effect of the microstructure of OCP crystals on long tubular bones has not been clarified. In this study, two types of OCPs with different microstructures, fine-OCP (F-OCP) and coarse-OCP (C-OCP), were implanted in rat tibia for 4 weeks. F-OCP promoted cortical bone regeneration compared with C-OCP. The osteoclasts appearance was significantly higher in the C-OCP group than in the control group (defect only) at 1-week post-implantation. To investigate whether the solubility equilibrium depends on the different particle sizes of OCPs, Nano-OCP, which consisted of nanometer-sized OCPs, was prepared. The degree of supersaturation (DS) tended to decrease modestly in the order of C-OCP, F-OCP, and Nano-OCP with respect to HA and OCP in Tris-HCl buffer. F-OCP showed a higher phosphate ion concentration and lower calcium ion concentration after immersion in the buffer than C-OCP. The crystal structures of both OCPs tended to be converted to HA by rat abdominal implantation. These results suggest that differences in the microstructure of OCPs may affect osteoclastogenesis and result in osteoconductivity of this material in long tubular bone by altering dissolution behavior.


2010 ◽  
Vol 101 (4) ◽  
pp. 713-716 ◽  
Author(s):  
W. Mróz ◽  
A. Bombalska ◽  
B. Budner ◽  
S. Burdyńska ◽  
M. Jedyński ◽  
...  

2019 ◽  
Vol 798 ◽  
pp. 83-87
Author(s):  
Faungchat Thammarakcharoen ◽  
Ariya Yampakdee ◽  
Bovornwut Buranawat ◽  
Jintamai Suwanprateeb

Granule characteristics and the agglomeration ability of 3D printed hydroxyapatite granules (3DP HA) when contacting water were compared to those of commercial bone graft granules based on hydroxyapatite/β-tricalcium phosphate/collagen mixture (Sunmax). Microstructure, phase composition, water absorption and granular agglomeration of the granules were characterized. SEM showed that the granule sizes of Sunmax were in the range of 0.8-1.5 mm whereas that of 3DP HA was relatively more uniform at about 1 mm. 3DP HA granules comprised the weaving of numerous minute crystals containing large pores and having high porosity while Sunmax granules were crushed granules and having low porosity. XRD analysis confirmed that Sunmax granules were biphasic hydroxyapatite and β-tricalcium phosphate while 3DP HA granules were monophasic hydroxyapatite. Sunmax granules exhibited greater agglomeration volume than that of 3DP HA granules. However, the water absorption of 3DP HA granules was greater than that of Sunmax granules. The greater agglomeration ability of Sunmax granules was likely due to the collagen constituent of the granules which could act as adhesive to bind granules together in addition to water capillary action. In contrast, 3DP HA granules formed the agglomeration by the water film due to the capillary action only so the efficiency was lower although the water absorption was greater.


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