Phenylsulfonic acid functionalized carbon quantum dots based biosensor for acetylcholinesterase activity monitoring and inhibitor screening

RSC Advances ◽  
2016 ◽  
Vol 6 (107) ◽  
pp. 105454-105460 ◽  
Author(s):  
Fengqi Zhou ◽  
Hui Feng ◽  
Yafen Fang ◽  
Qian Sun ◽  
Zhaosheng Qian

Phenylsulfonic acid functionalized carbon quantum dots (PSA-CQDs) were prepared and used to construct a convenient and reliable fluorometric biosensor for acetylcholinesterase (AChE) activity and inhibitor screening.

2016 ◽  
Vol 222 ◽  
pp. 879-886 ◽  
Author(s):  
Zhaosheng Qian ◽  
Lujing Chai ◽  
Cong Tang ◽  
Yuanyuan Huang ◽  
Jianrong Chen ◽  
...  

2020 ◽  
Vol 159 ◽  
pp. 105456
Author(s):  
Saipeng Huang ◽  
Wenshuai Li ◽  
Xin Zhou ◽  
Mengyao Xie ◽  
Qing Luo ◽  
...  

2015 ◽  
Vol 87 (14) ◽  
pp. 7332-7339 ◽  
Author(s):  
Zhaosheng Qian ◽  
Lujing Chai ◽  
Qian Zhou ◽  
Yuanyuan Huang ◽  
Cong Tang ◽  
...  

The Analyst ◽  
2020 ◽  
Vol 145 (24) ◽  
pp. 8022-8029
Author(s):  
Lei Ren ◽  
Hongdan Li ◽  
Mei Liu ◽  
Jianxiu Du

The exposure of 365 nm light irradiation significantly accelerates the oxidase-mimicking activity of black phosphorus quantum dots, allowing sensitive colorimetric assay of acetylcholinesterase activity and evaluation of its inhibitor screening.


2017 ◽  
Vol 5 (11) ◽  
pp. 2826-2832 ◽  
Author(s):  
Hang Ao ◽  
Hui Feng ◽  
Xiaolu Huang ◽  
Meizhi Zhao ◽  
Zhaosheng Qian

A reversible fluorescence nanoswitch based on dynamic covalent B–O bonds that responds to the external stimulus of pH was developed, and further utilized to monitor α-glucosidase activity.


RSC Advances ◽  
2018 ◽  
Vol 8 (23) ◽  
pp. 12785-12790 ◽  
Author(s):  
Chunhua He ◽  
Huipeng Zhou ◽  
Ejaz Hussain ◽  
Yunyi Zhang ◽  
Niu Niu ◽  
...  

The PDI-DHA can aggregate to form supramolecular assemblies when mixed with lauroylcholine and lauric acid, and is employed as a ratiometric fluorescence probe for the detection of AChE activity.


2020 ◽  
Vol 0 (4) ◽  
pp. 29-32
Author(s):  
B.M. GAREEV ◽  
◽  
A.M. ABDRAKHMANOV ◽  
G.L. SHARIPOV ◽  
◽  
...  

The photoluminescence of carbon quantum dots synthesized from natural honey and mixtures of honey and sugar has been studied. An increase in the sugar content leads to a decrease in the photoluminescence intensity without changing the shape of the luminescence spectrum of these quantum dots aqueous solutions, which is associated with a decrease in the yield of their synthesis in the sugar presence. The discovered effect can be used to detect sugar in honey. When examining five different market samples of flower honey using this method, two of them showed a significant decrease in the photoluminescence intensity. A laboratory test for compliance with GOST 19792-2017 Standard requirements established an excess of the sucrose content in these samples. Luminescent determination of sugar in honey does not require complicated equipment and can be used to develop a new analytical method for determining the sugar content in counterfeit natural honey.


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