Engineered gold nanoparticles for photothermal cancer therapy and bacteria killing

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 111482-111516 ◽  
Author(s):  
Alireza Gharatape ◽  
Soodabeh Davaran ◽  
Roya Salehi ◽  
Hamed Hamishehkar
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Bacteria Killing

Gold nanoparticle mediated photothermal therapy in future medicine.

Recent advances in combinatorial cancer therapy via multifunctionalized gold nanoparticles

Nanomedicine ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. 1221-1237
Author(s):  
Touqeer Ahmad ◽  
Rizwana Sarwar ◽  
Ayesha Iqbal ◽  
Uzma Bashir ◽  
Umar Farooq ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Targeted Drug Delivery ◽  
Photothermal Therapy ◽  
Therapeutic Implications ◽  
Therapeutic Applications ◽  
Diagnosis Of Cancer ◽  
Targeted Drug ◽  
Cancerous Cells

The diverse behavior of nanogold in the therapeutic field is related to its unique size and shape. Nanogold offers improvements in modern diagnostic and therapeutic implications, increases disease specificity and targeted drug delivery, and is relatively economical compared with other chemotherapeutic protocols. The diagnosis of cancer and photothermal therapy improve drastically with the implementation of nanotechnology. Different types of nanoparticles, that is, gold silica nanoshells, nanorods and nanospheres of diverse shapes and geometries, are used widely in the photothermal therapy of cancerous cells and nodules. Numerous reviews have been published on the therapeutic applications of gold nanoparticles, but studies on combinatorial applications of nanogold in cancer therapy are limited. This review focuses on the combinatorial cancer therapy using optical properties of nanogold with different shapes and geometries, and their therapeutic applications in cancer diagnosis, photothermal therapy, cancer imaging and targeted drug delivery.

scholarly journals Photosensitiser-gold nanoparticle conjugates for photodynamic therapy of cancer

2018 ◽  
Vol 17 (11) ◽  
pp. 1534-1552 ◽  
Author(s):  
Paula García Calavia ◽  
Gordon Bruce ◽  
Lluïsa Pérez-García ◽  
David A. Russell
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
State Of The Art ◽  
The State ◽  
Photodynamic Therapy Of Cancer ◽  
Photodynamic Cancer Therapy

A review describing the state-of-the-art of the functionalisation of gold nanoparticles with photosensitisers and targeting ligands for photodynamic cancer therapy.

Enzyme-triggered self-assembly of gold nanoparticles for enhanced retention effects and photothermal therapy of prostate cancer

2018 ◽  
Vol 54 (70) ◽  
pp. 9841-9844 ◽  
Author(s):  
Shuyan Yang ◽  
Defan Yao ◽  
Yanshu Wang ◽  
Weitao Yang ◽  
Bingbo Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gold Nanoparticles ◽  
Targeted Therapy ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Photothermal Therapy

A peptide-modified gold nanoparticle was developed for tumour-targeted therapy.

scholarly journals Effects of macrophage polarization on gold nanoparticle-assisted plasmonic photothermal therapy

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 25047-25056
Author(s):  
Hala R. Ali ◽  
Salah A. Selim ◽  
Daniel Aili
Keyword(s):  
Gold Nanoparticles ◽  
Laser Irradiation ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Macrophage Polarization ◽  
Preferential Uptake ◽  
M2 Phenotype ◽  
Plasmonic Photothermal Therapy

A preferential uptake of gold nanoparticles by macrophages with a protumoral M2 phenotype result in efficient killing upon laser irradiation while keeping M1 phenotypes relatively undamaged.

Light-responsible DNA hydrogel–gold nanoparticle assembly for synergistic cancer therapy

2015 ◽  
Vol 3 (8) ◽  
pp. 1537-1543 ◽  
Author(s):  
Jaejung Song ◽  
Sekyu Hwang ◽  
Kyuhyun Im ◽  
Jaehyun Hur ◽  
Jutaek Nam ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
Nanoparticle Assembly ◽  
Delivery Vehicle ◽  
Combination Cancer Therapy ◽  
Synergistic Combination ◽  
Dna Hydrogel

A DNA hydrogel based delivery vehicle that combines assembled gold nanoparticles and Doxorubicins showed light-triggered and synergistic combination cancer therapy at the in vitro and in vivo levels.

scholarly journals Near-Infrared-Responsive Cancer Photothermal and Photodynamic Therapy Using Gold Nanoparticles

Polymers ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 961 ◽  
Author(s):  
Hyung Kim ◽  
Dong Lee
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
Near Infrared ◽  
Energy Conversion Efficiency ◽  
Biological Properties ◽  
Drug Delivery Carrier ◽  
Thermal Energy Conversion ◽  
Gold Nanocomposites

Rapid growth of nanotechnology is one of the most quickly emerging tendencies in cancer therapy. Gold nanoparticles roused a distinctive interest in the field, due to their incomparable light-to-thermal energy conversion efficiency, and their ability to load and deliver a variety of anticancer drugs. Therefore, simultaneous photothermal (PTT) and photodynamic (PDT) cancer therapy is available by the role of the thermal agent of the gold nanoparticle itself and the drug delivery carrier for photosensitizer (PS) transport. In this review, the physical, chemical, and biological properties of gold nanoparticle, which can promote PTT and PDT efficiency, are briefly demonstrated, and we highlight recent progression in the development of PS-containing gold nanocomposites for effective cancer therapy.

scholarly journals Gold Nanoparticle Mediated Phototherapy for Cancer

2016 ◽  
Vol 2016 ◽  
pp. 1-29 ◽  
Author(s):  
Cuiping Yao ◽  
Luwei Zhang ◽  
Jing Wang ◽  
Yulu He ◽  
Jing Xin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Properties ◽  
Radiation Therapy ◽  
Photodynamic Therapy ◽  
Adverse Effects ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Drug Carrier ◽  
Cancer Treatments ◽  
Medical Diagnostic

Gold nanoparticles exhibit very unique physiochemical and optical properties, which now are extensively studied in range of medical diagnostic and therapeutic applications. In particular, gold nanoparticles show promise in the advancement of cancer treatments. This review will provide insights into the four different cancer treatments such as photothermal therapy, gold nanoparticle-aided photodynamic therapy, gold nanoparticle-aided radiation therapy, and their use as drug carrier. We also discuss the mechanism of every method and the adverse effects and its limitations.

scholarly journals Comparison of Four Common Gold Nanoparticles for Photothermal Cancer Therapy: A Review

2020 ◽  
Vol 5 (4) ◽  
pp. 116-129
Author(s):  
Sabrina N. Saiphoo ◽  
Cassidy M. Rose ◽  
Alexander T. Dunn ◽  
Dwij J. Padia ◽  
Muhammad Hasibul Hasan
Keyword(s):  
Gold Nanoparticles ◽  
Side Effects ◽  
Cancer Therapy ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Treatment Options ◽  
Infrared Light ◽  
Gold Nanospheres ◽  
Cancerous Tissue ◽  
Patient Prognosis

Current cancer treatment options, including surgery, chemotherapy and radiation therapy, often cause damage to healthy tissue and reduce a patient's quality of life with well-known side effects, such as pain, infection and nerve damage. Recent research has shown that gold nanoparticles used as photothermal agents in photothermal therapy may pose as an alternative to traditional treatments. This great potential is due to their ability to selectively accumulate in cancerous tissue, efficiently absorb near-infrared light, and kill cancerous tissue without harming surrounding cells. Gold nanoparticles show promise in increasing treatment efficacy and reducing the side effects associated with cancer therapy. While recent studies show the potential of gold nanoparticles, the existing literature is limited in drawing comparisons between studies and practical use for photothermal therapy. This paper reviews notable studies on four common gold nanoparticles used in the therapeutic treatment of cancer: gold nanocages, gold nanospheres, gold nanorods, and gold nanoshells. By comparing key characteristics of the particles’, including their synthesis, toxicity, absorption spectrum, and selective photothermal lethality, gold nanospheres can be recommended for use in photothermal therapy. Although forms of each gold nanoparticle were found to have a low toxicity, gold nanospheres can be rapidly synthesized and appear to exceed in selective photothermal lethality and immature tumour accumulation. Due to these advantages in using gold nanospheres for photothermal therapy, cancer could be treated more effectively and improve patient prognosis.

Facile size-controlled synthesis of fucoidan-coated gold nanoparticles and cooperative anticancer effect with doxorubicin

2017 ◽  
Vol 5 (30) ◽  
pp. 6147-6153 ◽  
Author(s):  
Hongje Jang ◽  
Kyungtae Kang ◽  
Mostafa A. El-Sayed
Keyword(s):  
Gold Nanoparticles ◽  
Surface Modification ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
Controlled Synthesis ◽  
Anticancer Effect ◽  
One Pot ◽  
Highly Efficient ◽  
One Pot Synthesis ◽  
Size Controlled

Facile one-pot synthesis, surface modification and doxorubicin conjugation of anticancer biopolymer fucoidan coated gold nanoparticle enabled highly efficient cancer therapy through cooperative treatment feasibility.

Nanotheranostics for Cancer Therapy and Detection: State of the Art

2020 ◽  
Vol 26 (42) ◽  
pp. 5503-5517
Author(s):  
Shivani Rai Paliwal ◽  
Rameshroo Kenwat ◽  
Sabyasachi Maiti ◽  
Rishi Paliwal
Keyword(s):  
Carbon Nanotubes ◽  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Photothermal Therapy ◽  
State Of The Art ◽  
Cellular Level ◽  
Inorganic Materials ◽  
Simultaneous Imaging ◽  
Specific Targeting ◽  
Organ Tissue

Nanotheranostics, an approach of combining both diagnosis and therapy, is one of the latest advances in cancer therapy particularly. Nanocarriers designed and derived from inorganic materials such as like gold nanoparticles, silica nanoparticles, magnetic nanoparticles and carbon nanotubes have been explored for tremendous applications in this area. Similarly, nanoparticles composed of some organic material alone or in combination with inorganic nano-cargos have been developed pre-clinically and possess excellent features desired. Photothermal therapy, MRI, simultaneous imaging and delivery, and combination chemotherapy with a diagnosis are a few of the known methods exploring cancer therapy and detection at organ/tissue/molecular/sub-cellular level. This review comprises an overview of the recent reports meant for nano theranostics purposes. Targeted cancer nanotheranostics have been included for understating tumor micro-environment or cell-specific targeting approach employed. A brief account of various strategies is also included for the readers highlighting the mechanism of cancer therapy.

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