scholarly journals Gold Nanoparticle Mediated Phototherapy for Cancer

2016 ◽  
Vol 2016 ◽  
pp. 1-29 ◽  
Author(s):  
Cuiping Yao ◽  
Luwei Zhang ◽  
Jing Wang ◽  
Yulu He ◽  
Jing Xin ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Properties ◽  
Radiation Therapy ◽  
Photodynamic Therapy ◽  
Adverse Effects ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Drug Carrier ◽  
Cancer Treatments ◽  
Medical Diagnostic

Gold nanoparticles exhibit very unique physiochemical and optical properties, which now are extensively studied in range of medical diagnostic and therapeutic applications. In particular, gold nanoparticles show promise in the advancement of cancer treatments. This review will provide insights into the four different cancer treatments such as photothermal therapy, gold nanoparticle-aided photodynamic therapy, gold nanoparticle-aided radiation therapy, and their use as drug carrier. We also discuss the mechanism of every method and the adverse effects and its limitations.

scholarly journals Photosensitiser-gold nanoparticle conjugates for photodynamic therapy of cancer

2018 ◽  
Vol 17 (11) ◽  
pp. 1534-1552 ◽  
Author(s):  
Paula García Calavia ◽  
Gordon Bruce ◽  
Lluïsa Pérez-García ◽  
David A. Russell
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
State Of The Art ◽  
The State ◽  
Photodynamic Therapy Of Cancer ◽  
Photodynamic Cancer Therapy

A review describing the state-of-the-art of the functionalisation of gold nanoparticles with photosensitisers and targeting ligands for photodynamic cancer therapy.

Enzyme-triggered self-assembly of gold nanoparticles for enhanced retention effects and photothermal therapy of prostate cancer

2018 ◽  
Vol 54 (70) ◽  
pp. 9841-9844 ◽  
Author(s):  
Shuyan Yang ◽  
Defan Yao ◽  
Yanshu Wang ◽  
Weitao Yang ◽  
Bingbo Zhang ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Gold Nanoparticles ◽  
Targeted Therapy ◽  
Gold Nanoparticle ◽  
Self Assembly ◽  
Photothermal Therapy

A peptide-modified gold nanoparticle was developed for tumour-targeted therapy.

scholarly journals Gold–silica quantum rattles for multimodal imaging and therapy

2015 ◽  
Vol 112 (7) ◽  
pp. 1959-1964 ◽  
Author(s):  
Mathew Hembury ◽  
Ciro Chiappini ◽  
Sergio Bertazzo ◽  
Tammy L. Kalber ◽  
Glenna L. Drisko ◽  
...  
Keyword(s):  
Quantum Dots ◽  
Gold Nanoparticles ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Drug Carrier ◽  
Material Design ◽  
Tumor Burden ◽  
Silica Shell ◽  
Innovative Material

Gold quantum dots exhibit distinctive optical and magnetic behaviors compared with larger gold nanoparticles. However, their unfavorable interaction with living systems and lack of stability in aqueous solvents has so far prevented their adoption in biology and medicine. Here, a simple synthetic pathway integrates gold quantum dots within a mesoporous silica shell, alongside larger gold nanoparticles within the shell’s central cavity. This “quantum rattle” structure is stable in aqueous solutions, does not elicit cell toxicity, preserves the attractive near-infrared photonics and paramagnetism of gold quantum dots, and enhances the drug-carrier performance of the silica shell. In vivo, the quantum rattles reduced tumor burden in a single course of photothermal therapy while coupling three complementary imaging modalities: near-infrared fluorescence, photoacoustic, and magnetic resonance imaging. The incorporation of gold within the quantum rattles significantly enhanced the drug-carrier performance of the silica shell. This innovative material design based on the mutually beneficial interaction of gold and silica introduces the use of gold quantum dots for imaging and therapeutic applications.

scholarly journals Surface-confined core–shell structures based on gold nanoparticles and metal–organic networks

2014 ◽  
Vol 50 (35) ◽  
pp. 4635-4638 ◽  
Author(s):  
Revital Kaminker ◽  
Michal Lahav ◽  
Marc Altman ◽  
Guennadi Evmenenko ◽  
Pulak Dutta ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Properties ◽  
Gold Nanoparticle ◽  
Shell Structures ◽  
Core Shell ◽  
Metal Organic ◽  
Organic Networks

A gold nanoparticle platform enhances the optical properties and order in a metal–organic network (MON).

scholarly journals Effects of macrophage polarization on gold nanoparticle-assisted plasmonic photothermal therapy

RSC Advances ◽  
2021 ◽  
Vol 11 (40) ◽  
pp. 25047-25056
Author(s):  
Hala R. Ali ◽  
Salah A. Selim ◽  
Daniel Aili
Keyword(s):  
Gold Nanoparticles ◽  
Laser Irradiation ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Macrophage Polarization ◽  
Preferential Uptake ◽  
M2 Phenotype ◽  
Plasmonic Photothermal Therapy

A preferential uptake of gold nanoparticles by macrophages with a protumoral M2 phenotype result in efficient killing upon laser irradiation while keeping M1 phenotypes relatively undamaged.

Engineered gold nanoparticles for photothermal cancer therapy and bacteria killing

RSC Advances ◽  
2016 ◽  
Vol 6 (112) ◽  
pp. 111482-111516 ◽  
Author(s):  
Alireza Gharatape ◽  
Soodabeh Davaran ◽  
Roya Salehi ◽  
Hamed Hamishehkar
Keyword(s):  
Gold Nanoparticles ◽  
Cancer Therapy ◽  
Gold Nanoparticle ◽  
Photothermal Therapy ◽  
Bacteria Killing

Gold nanoparticle mediated photothermal therapy in future medicine.

scholarly journals An Overview of the Synthesis of Gold Nanoparticles Using Radiation Technologies

Nanomaterials ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 939 ◽  
Author(s):  
Lucas Freitas de Freitas ◽  
Gustavo Varca ◽  
Jorge dos Santos Batista ◽  
Ademar Benévolo Lugão
Keyword(s):  
Gold Nanoparticles ◽  
Optical Properties ◽  
Gold Nanoparticle ◽  
Reducing Agents ◽  
Single Step ◽  
Nucleation Process ◽  
Size And Shape ◽  
Radiation Sources ◽  
Radiolytic Synthesis

At a nano-level, optical properties of gold are unique and gave birth to an emerging platform of nanogold-based systems for diverse applications, because gold nanoparticle properties are tunable as a function of size and shape. Within the available techniques for the synthesis of gold nanoparticles, the radiolytic synthesis allows proper control of the nucleation process without the need for reducing agents, in a single step, combined or not with simultaneous sterilization. This review details and summarizes the use of radiation technologies for the synthesis and preparation of gold nanoparticles concerning fundamental aspects, mechanism, current pathways for synthesis and radiation sources, as well as briefly outlines final applications and some toxicity aspects related to nanogold-based systems.

scholarly journals Delivery of a hydrophobic phthalocyanine photosensitizer using PEGylated gold nanoparticle conjugates for the in vivo photodynamic therapy of amelanotic melanoma

2016 ◽  
Vol 15 (5) ◽  
pp. 618-625 ◽  
Author(s):  
Monica Camerin ◽  
Miguel Moreno ◽  
María J. Marín ◽  
Claire L. Schofield ◽  
Isabelle Chambrier ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Photodynamic Therapy ◽  
Gold Nanoparticle ◽  
Amelanotic Melanoma

Gold nanoparticles functionalised with PEG and a phthalocyanine photosensitiser achieved 40% no tumour regrowth and complete survival followingin vivoPDT.

In situ hydrosilane reduction and preparation of gold nanoparticle–gel glass composites with nonlinear optical properties

2018 ◽  
Vol 6 (21) ◽  
pp. 5624-5629 ◽  
Author(s):  
Dajiang Yu ◽  
Xingming Sun ◽  
Xin Chen ◽  
Wencan Ma ◽  
Jibin Sun ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Optical Properties ◽  
Gold Nanoparticle ◽  
Nonlinear Optical ◽  
Optical Limiting ◽  
Nonlinear Optical Properties ◽  
Glass Composites

Gold nanoparticles were reduced in situ by a new hydrosilane reductant in organosilicon oligomer to fabricate nonlinear optical limiting materials.

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