Facile carbohydrate-mimetic modifications of poly(ethylene imine) carriers for gene delivery applications

2016 ◽  
Vol 7 (37) ◽  
pp. 5862-5872 ◽  
Author(s):  
Christoph Englert ◽  
Mareva Fevre ◽  
Rudy J. Wojtecki ◽  
Wei Cheng ◽  
Qingxing Xu ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Chemically Modified ◽  
Poly Ethylene

PEI was chemically-modified with carbohydrates and carbohydrate-mimetics to improve biocompatibility.

Integrin ανβ3Targeted Gene Delivery Using RGD Peptidomimetic Conjugates with Copolymers of PEGylated Poly(ethylene imine)

2009 ◽  
Vol 20 (6) ◽  
pp. 1270-1280 ◽  
Author(s):  
Olivia M. Merkel ◽  
Oliver Germershaus ◽  
Carol K. Wada ◽  
Peter J. Tarcha ◽  
Thomas Merdan ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Poly Ethylene

Dextran-graft-linear poly(ethylene imine)s for gene delivery: Importance of the linking strategy

2014 ◽  
Vol 113 ◽  
pp. 597-606 ◽  
Author(s):  
Sofia Ochrimenko ◽  
Antje Vollrath ◽  
Lutz Tauhardt ◽  
Kristian Kempe ◽  
Stephanie Schubert ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Linear Poly ◽  
Poly Ethylene

The Synthesis of Cyclic Poly(ethylene imine) and Exact Linear Analogues: An Evaluation of Gene Delivery Comparing Polymer Architectures

2015 ◽  
Vol 137 (20) ◽  
pp. 6541-6549 ◽  
Author(s):  
Mallory A. Cortez ◽  
W T. Godbey ◽  
Yunlan Fang ◽  
Molly E. Payne ◽  
Brian J. Cafferty ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Polymer Architectures ◽  
Poly Ethylene

Poly(ethylene imine)-modified graphene oxide with improved colloidal stability and its adsorption of methyl orange

2014 ◽  
Vol 70 (5) ◽  
pp. 851-857 ◽  
Author(s):  
Hongxi Liu ◽  
Ting Wu ◽  
Zhimin Wu ◽  
Yong Zhang ◽  
Keqin Xuan ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Methyl Orange ◽  
Adsorption Capacity ◽  
Colloidal Stability ◽  
Ethylene Imine ◽  
Chemically Modified ◽  
Modified Graphene Oxide ◽  
Infrared Spectrometer ◽  
Poly Ethylene ◽  
Modified Graphene

Graphene oxide (GO) was chemically modified with poly(ethylene imine) (PEI) to improve its colloidal stability and was investigated as a potential adsorbent for the removal of methyl orange (MO). The synthesis of PEI-GO was verified with a Fourier transform infrared spectrometer and thermogravimetric analysis. A series of adsorption experiments were carried out to investigate the adsorption capacity of PEI-GO. Adsorption kinetics and thermodynamics studies were performed, and the thermodynamic parameters were calculated. The results showed that PEI could improve the colloidal stability of GO in aqueous solution, and the obtained PEI-GO showed a macroscopically homogeneous dispersion after more than three months. After standing for 90 days, the Brunauer–Emmett–Teller specific surface area of GO decreased from 353 to 214 m2 · g−1, while that of PEI-GO remained almost unchanged (from 432 to 413 m2 · g−1). The PEI-GO exhibited significantly faster kinetic and higher adsorption capacity for MO than GO. Moreover, PEI-GO had a good adsorption capacity in the acidic range, and the highest adsorption of MO occurred at pH = 6.0. The adsorption of MO on PEI-GO was an endothermic, spontaneous and physisorption process.

Biocompatibility and Efficacy of Oligomaltose-Grafted Poly(ethylene imine)s (OM-PEIs) for in Vivo Gene Delivery

2013 ◽  
Vol 10 (12) ◽  
pp. 4666-4675 ◽  
Author(s):  
Daniela Gutsch ◽  
Dietmar Appelhans ◽  
Sabrina Höbel ◽  
Brigitte Voit ◽  
Achim Aigner
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
In Vivo Gene Delivery ◽  
Poly Ethylene

scholarly journals In vivo targeted gene delivery to peripheral neurons mediated by neurotropic poly(ethylene imine)-based nanoparticles [Corrigendum]

2017 ◽  
Vol Volume 12 ◽  
pp. 5631-5632
Author(s):  
Cátia Lopes ◽  
Hugo Oliveira ◽  
Inês Estevão ◽  
Liliana Pires ◽  
Ana Paula Pêgo
Keyword(s):  
Gene Delivery ◽  
Ethylene Imine ◽  
Targeted Gene Delivery ◽  
Peripheral Neurons ◽  
Poly Ethylene
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