Covalent Attachment of Low Molecular Weight Poly(ethylene imine) Improves Tat Peptide Mediated Gene Delivery

2006 ◽  
Vol 18 (16) ◽  
pp. 2174-2178 ◽  
Author(s):  
F. Alexis ◽  
S.-L. Lo ◽  
S. Wang
Keyword(s):  
Molecular Weight ◽  
Gene Delivery ◽  
Covalent Attachment ◽  
Low Molecular Weight ◽  
Tat Peptide ◽  
Ethylene Imine ◽  
Poly Ethylene

Amphiphilic, low molecular weight poly(ethylene imine) derivatives with enhanced stability for efficient pulmonary gene delivery

2011 ◽  
Vol 13 (2) ◽  
pp. 123-133 ◽  
Author(s):  
Susanne Roesler ◽  
Felix P. V. Koch ◽  
Thomas Schmehl ◽  
Norbert Weissmann ◽  
Werner Seeger ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Gene Delivery ◽  
Low Molecular Weight ◽  
Ethylene Imine ◽  
Poly Ethylene ◽  
Enhanced Stability

Enhanced gene expression and reduced toxicity in mice using polyplexes of low-molecular-weight poly(ethylene imine) for pulmonary gene delivery

2009 ◽  
Vol 17 (8) ◽  
pp. 638-651 ◽  
Author(s):  
Elke Kleemann ◽  
Norman Jekel ◽  
Lea Ann Dailey ◽  
Susanne Roesler ◽  
Ludger Fink ◽  
...  
Keyword(s):  
Gene Expression ◽  
Molecular Weight ◽  
Gene Delivery ◽  
Low Molecular Weight ◽  
Ethylene Imine ◽  
Poly Ethylene ◽  
Reduced Toxicity

Poly(ethylene glycol) analogs grafted with low molecular weight poly(ethylene imine) as non-viral gene vectors

2010 ◽  
Vol 6 (7) ◽  
pp. 2650-2657 ◽  
Author(s):  
Zhenfang Zhang ◽  
Cuihong Yang ◽  
Yajun Duan ◽  
Yanming Wang ◽  
Jianfeng Liu ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Ethylene Glycol ◽  
Viral Gene ◽  
Low Molecular Weight ◽  
Poly Ethylene Glycol ◽  
Ethylene Imine ◽  
Gene Vectors ◽  
Poly Ethylene

Gene delivery with low molecular weight linear polyethylenimines

2005 ◽  
Vol 7 (10) ◽  
pp. 1287-1298 ◽  
Author(s):  
Miriam Breunig ◽  
Uta Lungwitz ◽  
Renate Liebl ◽  
Claudia Fontanari ◽  
Juergen Klar ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Gene Delivery ◽  
Low Molecular Weight

Co-liposomes of redox-active alkyl-ferrocene modified low MW branched PEI and DOPE for efficacious gene delivery in serum

2015 ◽  
Vol 3 (11) ◽  
pp. 2318-2330 ◽  
Author(s):  
Krishan Kumar ◽  
Gururaja Vulugundam ◽  
Paturu Kondaiah ◽  
Santanu Bhattacharya
Keyword(s):  
Molecular Weight ◽  
Gene Delivery ◽  
Low Molecular Weight ◽  
Redox Active ◽  
Branched Polyethylenimine

Ferrocenylated lipopolymers based on low molecular weight, branched polyethylenimine (BPEI 800 Da) for redox controlled gene delivery.

High-Speed Melt Spinning of Sheath-Core Bicomponent Polyester Fibers: High and Low Molecular Weight Poly(ethylene Terephthalate) Systems

1997 ◽  
Vol 67 (9) ◽  
pp. 684-694 ◽  
Author(s):  
J. Radhakrishnan ◽  
Takeshi Kikutani ◽  
Norimasa Okui
Keyword(s):  
Molecular Weight ◽  
High Speed ◽  
Melt Spinning ◽  
Ethylene Terephthalate ◽  
Maxwell Model ◽  
Low Molecular Weight ◽  
Structural Development ◽  
Solidification Temperature ◽  
Poly Ethylene Terephthalate ◽  
Poly Ethylene

Sheath-core bicomponent spinning of high molecular weight poly (ethylene terephthalate) (hmpet, IV = 1.02 dl/g) and low molecular weight pet (lmpet, IV = 0.65 dl/g) is done at a take-up velocity range of 1 to 7 km/min. The structures of the individual components in the as-spun bicomponent fibers are characterized. Orientation and orientation-induced crystallization of the hmpet component are enhanced, while those of the lmpet component are suppressed in comparison to corresponding single component spinning. Numerical simulation with the Newtonian model shows that elongational stress in the hmpet component is enhanced and that of the lmpet decreases during high-speed bicomponent spinning. The difference in elongational viscosity is the main factor influencing the mutual interaction between hmpet and lmpet, which in turn affect spinline dynamics, solidification temperature, and structural development in high-speed bicomponent spinning. Simulation with an upper-convected Maxwell model shows that considerable stress relaxation can occur in the lmpet component if the hmpet component solidifies before lmpet. A mechanism for structural development is also proposed, based on the simulation results and structural characterization data.

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