Efficient visualization of H2S via a fluorescent probe with three electrophilic centres

2016 ◽  
Vol 14 (15) ◽  
pp. 3690-3694 ◽  
Author(s):  
Sharad Kumar Asthana ◽  
Ajit Kumar ◽  
Neeraj Neeraj ◽  
Shweta Shweta ◽  
K. K. Upadhyay
Keyword(s):  
Response Time ◽  
Fluorescent Probe ◽  
High Sensitivity ◽  
Design Strategy ◽  
Optical Probe ◽  
Rapid Response

A meticulous design strategy of incorporating three electrophilic centres in an optical probe (FLA) led to the achievement of high sensitivity and rapid response time (40 s) towards H2S detection.

A coumarin-based dual optical probe for homocysteine with rapid response time, high sensitivity and selectivity

Talanta ◽  
2019 ◽  
Vol 196 ◽  
pp. 243-248 ◽  
Author(s):  
Kun-Peng Wang ◽  
Shengnan Xu ◽  
Yang Lei ◽  
Wen-Jun Zheng ◽  
Qi Zhang ◽  
...  
Keyword(s):  
Response Time ◽  
High Sensitivity ◽  
Optical Probe ◽  
Rapid Response ◽  
Sensitivity And Selectivity

Fast and sensitive fluorescent probe for ratiometric detection of hydrogen sulfide in mitochondria

2019 ◽  
Vol 11 (2) ◽  
pp. 232-235 ◽  
Author(s):  
Na Jiang ◽  
Bin Wang ◽  
Tao Liu ◽  
Qingyu Liu ◽  
Qin Wei ◽  
...  
Keyword(s):  
Hydrogen Sulfide ◽  
Response Time ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Fluorescent Dye ◽  
Rapid Response ◽  
Ratiometric Detection ◽  
In Cells

A hemicyanine-based fluorescent dye, Mito-BT, was developed to ratiometrically detect H2S. This dye was of high selectivity, photostability and sensitivity with a rapid response time of 10 seconds. In addition, Mito-BT was localized in mitochondria, making it a promising probe for detecting H2S in cells.

A reaction-based fluorescent turn-on probe for Cu2+ in complete aqueous solution

RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87110-87114 ◽  
Author(s):  
Dongjian Zhu ◽  
Yanghe Luo ◽  
Xiaowei Yan ◽  
Wei Xie ◽  
Wen Cai ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Response Time ◽  
High Selectivity ◽  
High Sensitivity ◽  
Rapid Response ◽  
Turn On

FP can detect Cu2+ in complete aqueous solution with a rapid response time, high sensitivity, and high selectivity.

Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

2014 ◽  
Vol 50 (63) ◽  
pp. 8640-8643 ◽  
Author(s):  
Ji-Ting Hou ◽  
Ming-Yu Wu ◽  
Kun Li ◽  
Jin Yang ◽  
Kang-Kang Yu ◽  
...  
Keyword(s):  
Response Time ◽  
Fluorescent Probes ◽  
In Vivo Imaging ◽  
High Sensitivity ◽  
Rapid Response ◽  
Excellent Selectivity

Two probes that exhibited high sensitivity and excellent selectivity toward ClO−among ROS with a rapid response time were presented, which could selectively detect ClO−in the mitochondria of the cells.

An HBT-based fluorescent probe for nitroreductase determination and its application in Escherichia coli cell imaging

2020 ◽  
Vol 44 (38) ◽  
pp. 16265-16268
Author(s):  
Quanzhi Yang ◽  
Yujie Wen ◽  
Aiguo Zhong ◽  
Jian Xu ◽  
Shijun Shao
Keyword(s):  
Escherichia Coli ◽  
Response Time ◽  
Fluorescent Probe ◽  
Cell Imaging ◽  
Stokes Shift ◽  
Rapid Response ◽  
Coli Cell ◽  
Excellent Performance ◽  
Long Wavelength ◽  
Wavelength Emission

HBTPN exhibited excellent performance such as rapid response time, large Stokes shift, good selectivity and sensitivity, and long-wavelength emission.

scholarly journals Preparation of novel imidazo[1,2-a]indole fluorophore and its application for detecting extreme pH of fungus

2021 ◽  
Author(s):  
Yanhao Xu ◽  
Ruikang Duan ◽  
Hao Liu ◽  
Chengcai Xia ◽  
Guiyun Duan ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Response Time ◽  
Fluorescent Probe ◽  
Indole Derivative ◽  
High Sensitivity ◽  
Strong Acid ◽  
Fast Response ◽  
Acidic Ph ◽  
Response Mechanism ◽  
Ph Conditions

Abstract A novel pH fluorescent probe imidazo[1,2-a]indole derivative is reported. The probe is highly selective to strong acidic pH (pKa = 3.56) with high sensitivity and a fast response time (within 30 s). It is hardly interfered by ordinary metal ions and has good reversibility under strong acid conditions. The probe transfers charge under different pH conditions, and the response mechanism depends on the change of ICT. It can also be used for imaging in strong acidic Saccharomyces cerevisiae and detection of intracellular H+ as well.

scholarly journals A fast response, self-powered and room temperature near infrared-terahertz photodetector based on a MAPbI3/PEDOT:PSS composite

2020 ◽  
Vol 8 (35) ◽  
pp. 12148-12154 ◽  
Author(s):  
Yifan Li ◽  
Yating Zhang ◽  
Tengteng Li ◽  
Xin Tang ◽  
Mengyao Li ◽  
...  
Keyword(s):  
Response Time ◽  
Room Temperature ◽  
Near Infrared ◽  
Fast Response ◽  
Rapid Response ◽  
Self Powered

A novel self-powered NIR and THz PTE PD based on a (MAPbI3/PEDOT:PSS) composite with a rapid response time of 28 μs.

Highly sensitive, stable, and precise detection of dopamine with carbon dots/tyrosinase hybrid as fluorescent probe

RSC Advances ◽  
2014 ◽  
Vol 4 (87) ◽  
pp. 46437-46443 ◽  
Author(s):  
Hao Li ◽  
Juan Liu ◽  
Manman Yang ◽  
Weiqian Kong ◽  
Hui Huang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Carbon Dots ◽  
Low Cost ◽  
High Sensitivity ◽  
Highly Sensitive

The carbon dots/tyrosinase hybrid as a low-cost fluorescent probe for the detection of dopamine exhibits high sensitivity, stability, and precision.

Genetically Engineered Pores as Metal Ion Biosensors

1993 ◽  
Vol 330 ◽  
Author(s):  
John Kasianowicz ◽  
Barbara Walker ◽  
Musti Krishnasastry ◽  
Hagan Bayley
Keyword(s):  
Response Time ◽  
Lipid Bilayers ◽  
Metal Ion ◽  
Dynamic Range ◽  
Divalent Cations ◽  
High Sensitivity ◽  
Genetically Engineered ◽  
Great Promise ◽  
Lipid Bilayer Membranes ◽  
Time Dynamic

ABSTRACTWe are adapting proteins that form pores in lipid bilayers for use as components of biosensors. Specifically, we have produced genetically engineered variants of the α hemolysin (αHL) fromStaphylococcusaureus with properties that are sensitive to low concentrations of divalent cations. For example, the pore-forming activity of one mutant (αHL-H5: residues 130–134 inclusive replaced with histidine) is inhibited by Zn2+at concentrations as low as 1 μM, as judged by the reduction in its ability to lyse rabbit red blood cells and to increase the conductance of planar lipid bilayer membranes. When αHL-H5 is added to the aqueous phase bathing one side of a planar membrane, the subsequent addition of 100 μM Zn2+to either side blocks the pores that form. This result suggests that at least part of the mutated region lines the channel lumen. Ca2+and Mg2+do not block the channel and therefore the H5 mutation confers a degree of analyte specificity to the αHL pore. The results suggest that genetically engineered pores have great promise for the rapid and sensitive detection of metal cations and we discuss the merits and potential limitations for their use in this application. Specifically, we examine the issues of selectivity, sensitivity, response time, dynamic range and longevity. Some of these properties are interdependent. For example, the goals of high sensitivity and rapid response time can be in conflict.

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