Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

2014 ◽  
Vol 50 (63) ◽  
pp. 8640-8643 ◽  
Author(s):  
Ji-Ting Hou ◽  
Ming-Yu Wu ◽  
Kun Li ◽  
Jin Yang ◽  
Kang-Kang Yu ◽  
...  
Keyword(s):  
Response Time ◽  
Fluorescent Probes ◽  
In Vivo Imaging ◽  
High Sensitivity ◽  
Rapid Response ◽  
Excellent Selectivity

Two probes that exhibited high sensitivity and excellent selectivity toward ClO−among ROS with a rapid response time were presented, which could selectively detect ClO−in the mitochondria of the cells.

In vivo imaging of hepatocellular nitric oxide using a hepatocyte-targeting fluorescent sensor

2018 ◽  
Vol 54 (52) ◽  
pp. 7231-7234 ◽  
Author(s):  
Peisheng Zhang ◽  
Yong Tian ◽  
Hui Liu ◽  
Junyu Ren ◽  
Hong Wang ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
In Vivo Imaging ◽  
Water Solubility ◽  
Fluorescent Sensor ◽  
High Sensitivity ◽  
No Sensor ◽  
Excellent Selectivity

A hepatocyte-targeting fluorescent NO sensor has been fabricated with good water solubility, excellent selectivity, and high sensitivity (∼1.62 nM).

scholarly journals Biological nanoscale fluorescent probes: From structure and performance to bioimaging

2020 ◽  
Vol 39 (1) ◽  
pp. 209-221
Author(s):  
Jiafeng Wan ◽  
Xiaoyuan Zhang ◽  
Kai Zhang ◽  
Zhiqiang Su
Keyword(s):  
Fluorescent Probes ◽  
Organic Dyes ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
High Sensitivity ◽  
Biological Imaging ◽  
Fluorescent Materials ◽  
And Performance

Abstract In recent years, nanomaterials have attracted lots of attention from researchers due to their unique properties. Nanometer fluorescent materials, such as organic dyes, semiconductor quantum dots (QDs), metal nano-clusters (MNCs), carbon dots (CDs), etc., are widely used in biological imaging due to their high sensitivity, short response time, and excellent accuracy. Nanometer fluorescent probes can not only perform in vitro imaging of organisms but also achieve in vivo imaging. This provides medical staff with great convenience in cancer treatment. Combined with contemporary medical methods, faster and more effective treatment of cancer is achievable. This article explains the response mechanism of three-nanometer fluorescent probes: the principle of induced electron transfer (PET), the principle of fluorescence resonance energy transfer (FRET), and the principle of intramolecular charge transfer (ICT), showing the semiconductor QDs, precious MNCs, and CDs. The excellent performance of the three kinds of nano fluorescent materials in biological imaging is highlighted, and the application of these three kinds of nano fluorescent probes in targeted biological imaging is also introduced. Nanometer fluorescent materials will show their significance in the field of biomedicine.

scholarly journals A fast response fluorescence probe specific for hypochlorous acid detection and its applications in bioimaging

2018 ◽  
Vol 16 (12) ◽  
pp. 2074-2082 ◽  
Author(s):  
Hongmin Jia ◽  
Shuhe Xia ◽  
Huan Feng ◽  
Qingtao Meng ◽  
Chengchen Duan ◽  
...  
Keyword(s):  
Hypochlorous Acid ◽  
Fluorescence Probe ◽  
High Sensitivity ◽  
Fast Response ◽  
Rapid Response

The features ofDNPH-NA, including its high sensitivity, selectivity, and reliability at physiological pH, together with a rapid response, enable its successful application in the detection of endogenous HOClin vitroandin vivo.

High-sensitivity in vivo imaging for tumors using a spectral up-conversion nanoparticle NaYF4: Yb3+, Er3+ in cooperation with a microtubulin inhibitor

Nanoscale ◽  
2012 ◽  
Vol 4 (13) ◽  
pp. 3901 ◽  
Author(s):  
Yanchun Wei ◽  
Qun Chen ◽  
Baoyan Wu ◽  
Aiguo Zhou ◽  
Da Xing
Keyword(s):  
In Vivo Imaging ◽  
High Sensitivity

Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation, and in Vivo Imaging

2016 ◽  
Vol 88 (3) ◽  
pp. 1944-1950 ◽  
Author(s):  
Hualong Fu ◽  
Peiyu Tu ◽  
Liu Zhao ◽  
Jiapei Dai ◽  
Boli Liu ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Amyloid Β ◽  
In Vitro Evaluation

A reaction-based fluorescent turn-on probe for Cu2+ in complete aqueous solution

RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87110-87114 ◽  
Author(s):  
Dongjian Zhu ◽  
Yanghe Luo ◽  
Xiaowei Yan ◽  
Wei Xie ◽  
Wen Cai ◽  
...  
Keyword(s):  
Aqueous Solution ◽  
Response Time ◽  
High Selectivity ◽  
High Sensitivity ◽  
Rapid Response ◽  
Turn On

FP can detect Cu2+ in complete aqueous solution with a rapid response time, high sensitivity, and high selectivity.

In Vivo Imaging of Ca2+, pH, and Reactive Oxygen Species Using Fluorescent Probes in Plants

2011 ◽  
Vol 62 (1) ◽  
pp. 273-297 ◽  
Author(s):  
Sarah J. Swanson ◽  
Won-Gyu Choi ◽  
Alexandra Chanoca ◽  
Simon Gilroy
Keyword(s):  
Reactive Oxygen Species ◽  
Fluorescent Probes ◽  
In Vivo Imaging ◽  
Reactive Oxygen ◽  
Oxygen Species

scholarly journals Activatable Organic Near-Infrared Fluorescent Probes Based on a Bacteriochlorin Platform: Synthesis and Multicolor in Vivo Imaging with a Single Excitation

2014 ◽  
Vol 25 (2) ◽  
pp. 362-369 ◽  
Author(s):  
Toshiko Harada ◽  
Kohei Sano ◽  
Kazuhide Sato ◽  
Rira Watanabe ◽  
Zhanqian Yu ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
In Vivo Imaging ◽  
Near Infrared

scholarly journals Near-infrared turn-on fluorescent probe for discriminative detection of Cys and application in in vivo imaging

RSC Advances ◽  
2019 ◽  
Vol 9 (71) ◽  
pp. 41431-41437 ◽  
Author(s):  
Shaolong Qi ◽  
Lubao Zhu ◽  
Xinyu Wang ◽  
Jianshi Du ◽  
Qingbiao Yang ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Biological Samples ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Signal To Noise Ratio ◽  
High Signal ◽  
Biological Detection ◽  
Signal To Noise ◽  
Turn On

Near-infrared (NIR) fluorescent probes are widely employed in biological detection because of their lower damage to biological samples, low background interference, and high signal-to-noise ratio.

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