Effect of ligand denticity on the nitric oxide reactivity of cobalt(ii) complexes

2016 ◽  
Vol 45 (27) ◽  
pp. 10979-10988 ◽  
Author(s):  
Hemanta Deka ◽  
Somnath Ghosh ◽  
Soumen Saha ◽  
Kuldeep Gogoi ◽  
Biplab Mondal
Keyword(s):  
Nitric Oxide ◽  
Metal Ion ◽  
Methanol Solution ◽  
Reductive Nitrosylation

NO reactivity of three Co(ii) complexes, 1, 2 and 3 have been studied in degassed methanol solution. The complexes differ from each other in terms of denticity and flexibility of the ligand fameworks. Complex 1 undergoes reductive nitrosylation of the metal ion; 2 results in corresponding [CoIII(NO−)] complex; whereas 3 does not react with NO.

Nitric oxide generation from S-nitrosoglutathione: New activity of indium and a survey of metal ion effects

Nitric Oxide ◽  
2019 ◽  
Vol 84 ◽  
pp. 16-21 ◽  
Author(s):  
Alec Lutzke ◽  
Alyssa C. Melvin ◽  
Megan J. Neufeld ◽  
Christopher L. Allison ◽  
Melissa M. Reynolds
Keyword(s):  
Nitric Oxide ◽  
Metal Ion ◽  
Ion Effects ◽  
Metal Ion Effects

Reductive nitrosylation of nickel(ii) complex by nitric oxide followed by nitrous oxide release

2016 ◽  
Vol 45 (25) ◽  
pp. 10200-10208 ◽  
Author(s):  
Somnath Ghosh ◽  
Hemanta Deka ◽  
Yuvraj B. Dangat ◽  
Soumen Saha ◽  
Kuldeep Gogoi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitrous Oxide ◽  
Complex Formation ◽  
Subsequent Reaction ◽  
Reductive Nitrosylation ◽  
No Releases ◽  
Nitrous Oxide Release

Ni(ii) complex of bis-(2-ethyl-4-methylimidazol-5-yl)methane in methanol undergoes reductive nitrosylation in presence of NO to afford the corresponding Ni(i)-nitrosyl intermediate. Subsequent reaction with additional NO releases N2O with Ni(ii)-nitrito complex formation.

Catalytic reduction of nitric oxide with propane over Pt-T (T: transition metal) ion exchanged mordenites

1997 ◽  
Vol 121-122 ◽  
pp. 421-424 ◽  
Author(s):  
Eiji Sakamoto ◽  
Takakazu Ohnishi ◽  
Akinori Okukawa ◽  
Tsuyoshi Arakawa
Keyword(s):  
Nitric Oxide ◽  
Transition Metal ◽  
Metal Ion ◽  
Catalytic Reduction ◽  
Transition Metal Ion

Reductive nitrosylation and S-nitrosation of hemoglobin in inhomogeneous nitric oxide solutions

Nitric Oxide ◽  
2004 ◽  
Vol 10 (2) ◽  
pp. 74-82 ◽  
Author(s):  
Tae H Han ◽  
Jon M Fukuto ◽  
James C Liao
Keyword(s):  
Nitric Oxide ◽  
Reductive Nitrosylation

scholarly journals N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization

1999 ◽  
Vol 18 (22) ◽  
pp. 6271-6281 ◽  
Author(s):  
Brian R. Crane ◽  
Robin J. Rosenfeld ◽  
Andrew S. Arvai ◽  
Dipak K. Ghosh ◽  
Sanjay Ghosh ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Metal Ion ◽  
Domain Swapping ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Terminal Domain ◽  
Oxide Synthase

Stability constants, enthalpies, and entropies for metal ion-lariat ether interactions in methanol solution

1984 ◽  
Vol 49 (26) ◽  
pp. 5080-5084 ◽  
Author(s):  
Richard B. Davidson ◽  
Reed M. Izatt ◽  
James J. Christensen ◽  
Rose Ann Schultz ◽  
Dennis M. Dishong ◽  
...  
Keyword(s):  
Stability Constants ◽  
Metal Ion ◽  
Methanol Solution ◽  
Lariat Ether

Aromatic C-nitrosation by a copper(ii)–nitrosyl complex

2015 ◽  
Vol 44 (4) ◽  
pp. 1829-1835 ◽  
Author(s):  
Kanhu Charan Rout ◽  
Biplab Mondal
Keyword(s):  
Nitric Oxide ◽  
Aromatic Ring ◽  
Methanol Solution ◽  
Sulphonic Acid ◽  
Nitrosyl Complex ◽  
P Addition

Addition of nitric oxide to the methanol solution of copper(ii) complex of 4-amino-3-hydroxy-1-sulphonic acid, resulted in the reduction of Cu(ii) center through unstable copper(ii)-nitrosyl intermediate. The reduction was accompanied with simultaneous C-nitrosation of the aromatic ring of the ligand.

scholarly journals Synthesis of N-Pyridin-2-ylmethyl and N-Quinolin-2-ylmethyl ­Substituted Ethane-1,2-diamines

SynOpen ◽  
2017 ◽  
Vol 01 (01) ◽  
pp. 0147-0155 ◽  
Author(s):  
Yi-Qiu Yang ◽  
Long-Zhi Ke ◽  
Gui-Fei Wang ◽  
Shu-Yong Song ◽  
Ming-Ning Qiu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Metal Ions ◽  
Targeted Delivery ◽  
Metal Ion ◽  
Synthesis And Characterization ◽  
Long Wavelength ◽  
Initial Work ◽  
Wavelength Light

Two N-(2-(bis(pyridin-2-ylmethyl)amino)ethyl)quinoline-2-carboxamides and two N-(2-(bis(quinolin-2-ylmethyl)amino)ethyl)quinoline-2-carboxamides have been synthesized. These structures contain five nitrogen atoms that can form coordinate bonds with metal ions such as Mn(II) and Fe(II). An additional coordinating bond can be formed between the metal ion and a neutral molecule of nitric oxide (NO). The resultant complexes are potentially useful agents for targeted delivery of NO to in vivo biological sites such as tumors, where the NO is released upon irradiation with long-wavelength light. Initial work involving the synthesis and characterization of these analogues is reported here.

The reaction of S-nitrosothiols with thiols at high thiol concentration

1998 ◽  
Vol 76 (6) ◽  
pp. 789-794 ◽  
Author(s):  
Andrew P Dicks ◽  
E Li ◽  
Andrew P Munro ◽  
Helen R Swift ◽  
D Lyn H. Williams
Keyword(s):  
Nitric Oxide ◽  
Metal Ion ◽  
Large Range ◽  
Ph Dependence ◽  
Large Excess ◽  
Marked Contrast ◽  
First Order ◽  
Thiolate Anion ◽  
Rapid Equilibrium

Reactions of S-nitrosothiols (RSNO) with their corresponding thiols (RSH) present in a large excess (>20-fold) proceed readily to give the disulfide. Ammonia is formed together with some nitrite anion, and these constitute >90% of the "nitrogen" products. This is in marked contrast with the reaction at low thiol concentration, where nitric oxide is the major initial "nitrogen" product, which is rapidly converted in the presence of oxygen in water to nitrite anion. Also in marked contrast to the "low thiol concentration" reaction, the reaction at high thiol concentration is not affected by added Cu2+, nor by the metal-ion scavenger EDTA. Kinetically all reactions were excellent first-order processes, and the reactions were also strictly first order in thiol concentration. A large range of nitrosothiols were studied and the generality of the reaction established. Some reactions of RSNO with other thiols (R'SH) were examined and the results readily interpreted in terms of a prior rapid equilibrium transnitrosation. The pH dependence for the reaction of S-nitrosocysteine with cysteine clearly showed that the reactive species is the cysteine thiolate anion. The results are discussed along with those of two other recent reports of these reactions, in terms of thiolate attack initially at the nitroso nitrogen atom, and subsequently at sulfur atoms, eliminating RSSR and yielding hydroxylamine, which is rapidly reduced by thiolate ion to ammonia. The results are also discussed in connection with the release of NO from nitrosothiols and with the important biological consequences, both for the in vivo reactions of NO and for the potential of nitrosothiols as NO-releasing drugs for medical use.Key words: S-nitrosothiols, thiols, nitric oxide, ammonia, nitrous oxide.

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