Reductive nitrosylation and S-nitrosation of hemoglobin in inhomogeneous nitric oxide solutions

Nitric Oxide ◽  
2004 ◽  
Vol 10 (2) ◽  
pp. 74-82 ◽  
Author(s):  
Tae H Han ◽  
Jon M Fukuto ◽  
James C Liao
Keyword(s):  
Nitric Oxide ◽  
Reductive Nitrosylation

Reductive nitrosylation of nickel(ii) complex by nitric oxide followed by nitrous oxide release

2016 ◽  
Vol 45 (25) ◽  
pp. 10200-10208 ◽  
Author(s):  
Somnath Ghosh ◽  
Hemanta Deka ◽  
Yuvraj B. Dangat ◽  
Soumen Saha ◽  
Kuldeep Gogoi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitrous Oxide ◽  
Complex Formation ◽  
Subsequent Reaction ◽  
Reductive Nitrosylation ◽  
No Releases ◽  
Nitrous Oxide Release

Ni(ii) complex of bis-(2-ethyl-4-methylimidazol-5-yl)methane in methanol undergoes reductive nitrosylation in presence of NO to afford the corresponding Ni(i)-nitrosyl intermediate. Subsequent reaction with additional NO releases N2O with Ni(ii)-nitrito complex formation.

Probing fundamental mechanisms of nitric oxide reactions with metal centers

2004 ◽  
Vol 76 (2) ◽  
pp. 335-350 ◽  
Author(s):  
P. C. Ford
Keyword(s):  
Nitric Oxide ◽  
Heme Proteins ◽  
Flash Photolysis ◽  
Chemical Properties ◽  
Water Soluble ◽  
Model Complexes ◽  
Metal Centers ◽  
Reductive Nitrosylation

Studies in this laboratory have been concerned with mapping the chemical properties and mechanisms of NO interactions with hemes and other metal centers. These are models relevant to the mammalian biology of nitric oxide, an important bioregulatory molecule. Presented here will be an overview of flash photolysis kinetics investigations of ferri- and ferro-heme nitrosyl formation in model complexes and several heme proteins. Also described will be ongoing studies of reductive nitrosylation mechanisms involving the reactions of NO with water-soluble Fe(III) porphyrins and ferri-heme proteins and of several Cu(II) model complexes.

Effect of ligand denticity on the nitric oxide reactivity of cobalt(ii) complexes

2016 ◽  
Vol 45 (27) ◽  
pp. 10979-10988 ◽  
Author(s):  
Hemanta Deka ◽  
Somnath Ghosh ◽  
Soumen Saha ◽  
Kuldeep Gogoi ◽  
Biplab Mondal
Keyword(s):  
Nitric Oxide ◽  
Metal Ion ◽  
Methanol Solution ◽  
Reductive Nitrosylation

NO reactivity of three Co(ii) complexes, 1, 2 and 3 have been studied in degassed methanol solution. The complexes differ from each other in terms of denticity and flexibility of the ligand fameworks. Complex 1 undergoes reductive nitrosylation of the metal ion; 2 results in corresponding [CoIII(NO−)] complex; whereas 3 does not react with NO.

The Reductive Nitrosylation of Hemoglobin: Low Nitric Oxide Effects and Mechanisms for N2O3 Formation

2010 ◽  
Vol 49 ◽  
pp. S121
Author(s):  
Jesus Tejero ◽  
Swati Basu ◽  
Christine Carlisle ◽  
Neil Hogg ◽  
S. Bruce King ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Reductive Nitrosylation

Localization of endothelial nitric oxide synthase in the normal and failing human atrial myocardium

1996 ◽  
Vol 54 ◽  
pp. 786-787
Author(s):  
Chi-Ming Wei ◽  
Margarita Bracamonte ◽  
Shi-Wen Jiang ◽  
Richard C. Daly ◽  
Christopher G.A. McGregor ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Heart Failure ◽  
Nitric Oxide Synthase ◽  
Endothelial Nitric Oxide Synthase ◽  
Cardiac Tissues ◽  
Mammalian Tissues ◽  
End Stage Heart Failure ◽  
End Stage ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Nitric oxide (NO) is a potent endothelium-derived relaxing factor which also may modulate cardiomyocyte inotropism and growth via increasing cGMP. While endothelial nitric oxide synthase (eNOS) isoforms have been detected in non-human mammalian tissues, expression and localization of eNOS in the normal and failing human myocardium are poorly defined. Therefore, the present study was designed to investigate eNOS in human cardiac tissues in the presence and absence of congestive heart failure (CHF).Normal and failing atrial tissue were obtained from six cardiac donors and six end-stage heart failure patients undergoing primary cardiac transplantation. ENOS protein expression and localization was investigated utilizing Western blot analysis and immunohistochemical staining with the polyclonal rabbit antibody to eNOS (Transduction Laboratories, Lexington, Kentucky).

Nitric Oxide Reduces Pressor Responsiveness During Ovine Hypoadrenocorticism

2001 ◽  
Vol 28 (5-6) ◽  
pp. 459-462
Author(s):  
Pini Orbach ◽  
Charles E Wood ◽  
Maureen Keller-Wood
Keyword(s):  
Nitric Oxide
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