Fabrication of PVCL-co-PMMA nanofibers with tunable volume phase transition temperatures and maintainable shape for anti-cancer drug release

RSC Advances ◽  
2015 ◽  
Vol 5 (80) ◽  
pp. 64944-64950 ◽  
Author(s):  
Zaiqian Yu ◽  
Hongjuan Gu ◽  
Dongyan Tang ◽  
Haitao Lv ◽  
Yonghui Ren ◽  
...  
Keyword(s):  
Phase Transition ◽  
Controlled Release ◽  
Drug Release ◽  
Anticancer Drugs ◽  
Cancer Drug ◽  
Volume Phase Transition ◽  
Transition Temperatures ◽  
Volume Phase ◽  
Anti Cancer ◽  
Phase Transition Temperatures

Thermo responsive PVCL-co-PMMA nanofibers for controlled release of anticancer drugs were fabricated. The thermo response temperatures of the nanofibers could be easily tuned, and the fibrous shapes could be maintained after heating–cooling cycles.

Triply-responsive OEG-based microgels and hydrogels: Regulation of swelling ratio, volume phase transition temperatures and mechanical properties

2021 ◽  
Author(s):  
Dongdong Lu ◽  
Mingning Zhu ◽  
Jing Jin ◽  
Brian R. Saunders
Keyword(s):  
Phase Transition ◽  
Biomedical Engineering ◽  
Volume Phase Transition ◽  
Swelling Ratio ◽  
Transition Temperatures ◽  
Ph Responsive ◽  
Network Systems ◽  
Volume Phase ◽  
Phase Transition Temperatures ◽  
Volume Swelling

Thermally- and pH-responsive microgels (MGs) and hydrogels are fascinating network systems that have been applied in biomedical engineering and sensing. The volume-swelling ratio (Q) and the volume-phase transition temperatures (VPTTs)...

scholarly journals A robust method to calculate the volume phase transition temperature (VPTT) for hydrogels and hybrids

RSC Advances ◽  
2017 ◽  
Vol 7 (84) ◽  
pp. 53192-53202 ◽  
Author(s):  
Sulalit Bandyopadhyay ◽  
Anuvansh Sharma ◽  
Muhammad Awais Ashfaq Alvi ◽  
Rajesh Raju ◽  
Wilhelm Robert Glomm
Keyword(s):  
Phase Transition ◽  
Transition Temperature ◽  
Phase Transition Temperature ◽  
Volume Phase Transition ◽  
Transition Temperatures ◽  
Robust Method ◽  
Volume Phase ◽  
Volume Phase Transition Temperature ◽  
Phase Transition Temperatures

Phase transition temperatures along with system reversibilities defined by a unique reversibility parameter have been developed in this study.

Enzyme-responsive sulfatocyclodextrin/prodrug supramolecular assembly for controlled release of anti-cancer drug chlorambucil

2019 ◽  
Vol 55 (7) ◽  
pp. 953-956 ◽  
Author(s):  
Xinran Guan ◽  
Yong Chen ◽  
Xuan Wu ◽  
Peiyu Li ◽  
Yu Liu
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Supramolecular Assembly ◽  
Controlled Drug Release ◽  
Cancer Drug ◽  
Anti Cancer

A supramolecular assembly constructed using sulfatocyclodextrin and choline modified chlorambucil exhibits excellent enzyme-response activity and controlled drug release.

Controlled Release of Growth Factor Using Poly(N-Isopropyl Acrylamide)Copolymer Hydrogels with Different Volume Phase Transition Temperatures

2005 ◽  
Vol 277-279 ◽  
pp. 77-81
Author(s):  
Young A Han ◽  
Jeong Ok Lim ◽  
Jin Hyun Choi ◽  
Byung Chul Ji
Keyword(s):  
Phase Transition ◽  
Transition Temperature ◽  
Phase Transition Temperature ◽  
Crosslinking Agent ◽  
Volume Phase Transition ◽  
Release Behavior ◽  
Volume Phase ◽  
Volume Phase Transition Temperature ◽  
Isopropyl Acrylamide ◽  
Phase Transition Temperatures

The release behavior of the basic fibroblast growth factor (bFGF) from copolymer hydrogels of N-isopropyl acrylamide (NIPAAm) and sodium methacrylate (SMA) was investigated in relation to the volume phase transition temperatures, which was increased by the incorporation of SMA. In the case of the copolymer hydrogels, a higher volume phase transition temperature was obtained when poly(ethylene glycol) diacrylate (PEGDA) was used as the crosslinking agent, suggesting that the chain length of the crosslinking agent has a significant affect on the volume phase transition temperature of a P(NIPAAm-co-SMA) hydrogel. The concentration of bFGF released from the hydrogels with PEGDA increased relative to the water content, thereby showing a dependence on the volume phase transition temperature. Hence, the release behavior of bFGF from the PNIPAAm and P(NIPAAm-co-SMA) hydrogels was found to be affected by the volume phase transition temperature, which can be easily controlled by changing the comonomer, monomer feed ratio, and crosslinking agent.

Diosgenin-conjugated PCL–MPEG polymeric nanoparticles for the co-delivery of anticancer drugs: design, optimization, in vitro drug release and evaluation of anticancer activity

2019 ◽  
Vol 43 (17) ◽  
pp. 6622-6635 ◽  
Author(s):  
Sevinc Ilkar Erdagi ◽  
Ufuk Yildiz
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Anticancer Drugs ◽  
Polymeric Nanoparticles ◽  
Cancer Drug ◽  
In Vitro Drug Release ◽  
Polymeric Nanoparticle ◽  
Anti Cancer ◽  
Cancer Drug Delivery

In this study, a polymeric nanoparticle-mediated dual anti-cancer drug delivery system was designed and developed.

Sign in / Sign up

Export Citation Format

Share Document