The effects of the aqueous extract and residue of Matcha on the antioxidant status and lipid and glucose levels in mice fed a high-fat diet

2016 ◽  
Vol 7 (1) ◽  
pp. 294-300 ◽  
Author(s):  
Ping Xu ◽  
Le Ying ◽  
Gaojie Hong ◽  
Yuefei Wang

Matcha is a kind of powdered green tea produced by grinding with a stone mill.

2021 ◽  
Author(s):  
Jie Li ◽  
Qiyang Chen ◽  
Xiuming Zhai ◽  
Dan Wang ◽  
Yujia Hou ◽  
...  

2011 ◽  
Vol 31 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Joanna Bajerska ◽  
Małgorzata Wozniewicz ◽  
Jan Jeszka ◽  
Slawomira Drzymala-Czyz ◽  
Jaroslaw Walkowiak

2020 ◽  
Vol 17 (10) ◽  
pp. 1126-1138
Author(s):  
Anawat KONGCHIAN ◽  
Narissara KEAWBOONLERT ◽  
Thanchanok BOONRAK ◽  
Sarai LOOKYEE ◽  
Krittiyaporn BUASRI ◽  
...  

Hyperlipidemia and obesity are risk factors that contribute to cardiovascular diseases, diabetes, and hypertension among the world’s population. The present study aimed to investigate the effects of green tea (Camellia sinesis) and Garcinia (Garcinia atroviridis) extracts in high-fat diet mice. The mice were fed with a high-fat diet and orally administrated extracts once daily. The extracts displayed a significant decrease in body weight, triglyceride, low-density lipoprotein (LDL) cholesterol, total cholesterol, atherosclerosis index (AI), and glucose levels in blood. High-density lipoprotein (HDL) cholesterol significantly increased. Treatment with the extracts reduced the lipid peroxidation marker, malondialdehyde (MDA), and indicated the pathohistology of lower fat cells deposited in liver tissues. In in vitro studies, the extracts have been identified to be capable of inhibiting the activity of amylase and glucoside enzymes and scavenging free radicals. Moreover, both green tea and Garcinia extracts showed non-toxicity as presented by the activity of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and blood urea nitrogen (BUN). In conclusion, the pathogenic factors involved in atherosclerosis were reduced by green tea and Garcinia extracts, and both extracts could be useful for better prevention and treatment of atherosclerosis and cardiovascular diseases.


2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Fabiola Rivera-Ramírez ◽  
Gerardo N. Escalona-Cardoso ◽  
Leticia Garduño-Siciliano ◽  
Carlos Galaviz-Hernández ◽  
Norma Paniagua-Castro

Obesity, type II diabetes, and hyperlipidaemia, which frequently coexist and are strongly associated with oxidative stress, increase the risk of cardiovascular disease. An increase in carbohydrate intake, especially of fructose, and a high-fat diet are both factors that contribute to the development of these metabolic disorders. In recent studies carried out in diabetic rats, authors reported thatIbervillea sonoraehad hypoglycaemic activity; saponins and monoglycerides present in the plant could be responsible for the effects observed. In the present study, we determined the effects of an aqueousI. sonoraeextract on a murine model of obesity and hyperglycaemia, induced by a high-calorie diet, and the relationship of these effects with hepatic oxidation. A high-fat diet over a period of 8 weeks induced weight gain in the mice and increased triglycerides and blood glucose levels. Simultaneous treatment withI. sonoraeaqueous extracts, at doses of 100, 200, and 400 mg/kg, decreased triglycerides and glycaemia levels, prevented an increase in body weight in a dose-dependent manner, and decreased hepatic lipid oxidation at a dose of 200 mg/kg. These data suggest that the aqueous extract fromI. sonoraeroot prevents obesity, dyslipidaemia, and hyperglycaemia induced by a hypercaloric diet; however, high doses may induce toxicity.


2019 ◽  
Vol 89 (1-2) ◽  
pp. 45-54
Author(s):  
Akemi Suzuki ◽  
André Manoel Correia-Santos ◽  
Gabriela Câmara Vicente ◽  
Luiz Guillermo Coca Velarde ◽  
Gilson Teles Boaventura

Abstract. Objective: This study aimed to evaluate the effect of maternal consumption of flaxseed flour and oil on serum concentrations of glucose, insulin, and thyroid hormones of the adult female offspring of diabetic rats. Methods: Wistar rats were induced to diabetes by a high-fat diet (60%) and streptozotocin (35 mg/kg). Rats were mated and once pregnancy was confirmed, were divided into the following groups: Control Group (CG): casein-based diet; High-fat Group (HG): high-fat diet (49%); High-fat Flaxseed Group (HFG): high-fat diet supplemented with 25% flaxseed flour; High-fat Flaxseed Oil group (HOG): high-fat diet, where soya oil was replaced with flaxseed oil. After weaning, female pups (n = 6) from each group were separated, received a commercial rat diet and were sacrificed after 180 days. Serum insulin concentrations were determined by ELISA, the levels of triiodothyronine (T3), thyroxine (T4) and thyroid-stimulating hormone (TSH) were determined by chemiluminescence. Results: There was a significant reduction in body weight at weaning in HG (−31%), HFG (−33%) and HOG (44%) compared to CG (p = 0.002), which became similar by the end of 180 days. Blood glucose levels were reduced in HFG (−10%, p = 0.044) when compared to CG, and there was no significant difference between groups in relation to insulin, T3, T4, and TSH after 180 days. Conclusions: Maternal severe hyperglycemia during pregnancy and lactation resulted in a microsomal offspring. Maternal consumption of flaxseed reduces blood glucose levels in adult offspring without significant effects on insulin levels and thyroid hormones.


2013 ◽  
Author(s):  
Marcos Hiromu Okuda ◽  
de Santana Aline Alves ◽  
Mayara Franzoi Moreno ◽  
Ana Claudia Hachul ◽  
Nelson Inacio Neto ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Mi-Bo Kim ◽  
Changhee Kim ◽  
Youngwoo Song ◽  
Jae-Kwan Hwang

Xanthorrhizol, a natural compound isolated fromCurcuma xanthorrhizaRoxb. (Java turmeric), has been reported to possess antioxidant and anticancer properties; however, its effects on metabolic disorders remain unknown. The aim of the present study was to evaluate the effects of xanthorrhizol (XAN) andC. xanthorrhizaextract (CXE) with standardized XAN on hyperglycemia and inflammatory markers in high-fat diet- (HFD-) induced obese mice. Treatment with XAN (10 or 25 mg/kg/day) or CXE (50 or 100 mg/kg/day) significantly decreased fasting and postprandial blood glucose levels in HFD-induced obese mice. XAN and CXE treatments also lowered insulin, glucose, free fatty acid (FFA), and triglyceride (TG) levels in serum. Epididymal fat pad and adipocyte size were decreased by high doses of XAN (26.6% and 20.1%) and CXE (25.8% and 22.5%), respectively. XAN and CXE treatment also suppressed the development of fatty liver by decreasing liver fat accumulation. Moreover, XAN and CXE significantly inhibited production of inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), interleukin-1β(IL-1β), and C-reactive protein (CRP) in adipose tissue (27.8–82.7%), liver (43.9–84.7%), and muscle (65.2–92.5%). Overall, these results suggest that XAN and CXE, with their antihyperglycemic and anti-inflammatory activities, might be used as potent antidiabetic agents for the treatment of type 2 diabetes.


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