Acid-triggered drug release from micelles based on amphiphilic oligo(ethylene glycol)–doxorubicin alternative copolymers

2014 ◽  
Vol 2 (43) ◽  
pp. 7612-7619 ◽  
Author(s):  
Ying Wang ◽  
Qiaojie Luo ◽  
Rui Sun ◽  
Guangyu Zha ◽  
Xiaodong Li ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Ph Sensitive ◽  
Triggered Drug Release

We prepared pH-sensitive amphiphilic oligo(ethylene glycol)–doxorubicin alternative conjugates for the controlled release of doxorubicin.

Controlled Release Behaviors of Ketoprofen from Matrix Polymer of Chitosan and poly(ethylene glycol)

2013 ◽  
Vol 813 ◽  
pp. 399-402
Author(s):  
Chimsook Thitipha ◽  
Thitiphan Chimsook
Keyword(s):  
Particle Size ◽  
Controlled Release ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Diffusion Method ◽  
Poly Ethylene Glycol ◽  
Matrix Polymer ◽  
Percentage Yield ◽  
Poly Ethylene ◽  
Composition Ratios

The aim of present work was to prepare floating microsphere of ketoprofen using matrix polymer of chitosan and poly (ethylene glycol) by solvent diffusion method. The floating microsphere of ketoprofen was prepared from matrix polymer of chitosan and poly (ethylene glycol) with various composition ratios and evaluated such as particle size, drug compatibility and drug release of microspheres. The scanning electron microscopy of microspheres confirmed their hollow structures with smooth surface. Formulation CPK 4 to CPK 6 exhibited the best controlled release pattern in ketoprofen. The concentration and size of poly (ethylene-glycol) affected the particle size, percentage yield and drug release of microspheres.

scholarly journals ATRP-based synthesis of a pH-sensitive amphiphilic block polymer and its self-assembled micelles with hollow mesoporous silica as DOX carriers for controlled drug release

RSC Advances ◽  
2021 ◽  
Vol 11 (48) ◽  
pp. 29986-29996
Author(s):  
Xiuxiu Qi ◽  
Hongmei Yan ◽  
Yingxue Li
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Self Assembly ◽  
Drug Loading ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
Core Shell ◽  
Assembly Process ◽  
Block Polymer ◽  
Hollow Mesoporous Silica

A pH-sensitive core–shell nanoparticle (HMS@C18@PSDMA-b-POEGMA) was developed via a self-assembly process as the carrier of anticancer drug doxorubicin (DOX) for drug loading and controlled release.

Drug release of pH-sensitive poly(l-aspartate)-b-poly(ethylene glycol) micelles with POSS cores

2014 ◽  
Vol 5 (2) ◽  
pp. 463-470 ◽  
Author(s):  
Yuji Pu ◽  
Longgui Zhang ◽  
Hui Zheng ◽  
Bin He ◽  
Zhongwei Gu
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Ph Sensitive ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Tumor extracellular pH-sensitive polymeric nanocarrier-grafted platinum(iv) prodrugs for improved intracellular delivery and cytosolic reductive-triggered release

2020 ◽  
Vol 11 (12) ◽  
pp. 2212-2221 ◽  
Author(s):  
Sheng-Qi Chen ◽  
Gang Song ◽  
Chen He ◽  
Mei Hou ◽  
Wei-Dong He ◽  
...  
Keyword(s):  
Drug Release ◽  
Tumor Cells ◽  
Intracellular Delivery ◽  
Ph Sensitive ◽  
Extracellular Ph ◽  
Triggered Release ◽  
Triggered Drug Release ◽  
Release Strategy ◽  
Polymeric Nanocarrier

Extracellular pH-sensitive Pt(iv)-based nanodrugs enable preferential toxicity to tumor cells via a selectively endocytosed and triggered drug release strategy.

scholarly journals pH-Sensitive N-doped carbon dots–heparin and doxorubicin drug delivery system: preparation and anticancer research

RSC Advances ◽  
2017 ◽  
Vol 7 (15) ◽  
pp. 9347-9356 ◽  
Author(s):  
Ming Zhang ◽  
Ping Yuan ◽  
Ninglin Zhou ◽  
Yutian Su ◽  
Maoni Shao ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Release ◽  
Drug Delivery System ◽  
Delivery System ◽  
Carbon Dots ◽  
Drug Carrier ◽  
Ph Sensitive ◽  
Triggered Drug Release ◽  
Model Drug ◽  
Doped Carbon Dots

In this study, doxorubicin (DOX) hydrochloride as a model drug, N-doped carbon dots as a drug carrier, and heparin as an auxiliary medicine were selected to design and prepare a multi-functional drug delivery system with pH-triggered drug release.

Biodegradable pH-Sensitive Poly(ethylene glycol) Nanocarriers for Allergen Encapsulation and Controlled Release

2015 ◽  
Vol 16 (10) ◽  
pp. 3103-3111 ◽  
Author(s):  
Hannah Pohlit ◽  
Iris Bellinghausen ◽  
Martina Schömer ◽  
Bärbel Heydenreich ◽  
Joachim Saloga ◽  
...  
Keyword(s):  
Controlled Release ◽  
Ethylene Glycol ◽  
Ph Sensitive ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

A remotely triggered drug release system with dot array-like configuration for controlled release of multiple drugs

2018 ◽  
Vol 53 (13) ◽  
pp. 9382-9392 ◽  
Author(s):  
Lingmei Guo ◽  
Shihui Wang ◽  
Yuan He ◽  
Rui Zheng ◽  
Lili Chen ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Release ◽  
Release System ◽  
Triggered Drug Release ◽  
Drug Release System ◽  
Multiple Drugs
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