Reduction‐responsive poly (ethylene glycol)‐dexamethasone biarm conjugate and its self‐assembled nanomicelles: Preparation, physicochemical characterization, and thiol‐triggered drug release

2019 ◽  
Vol 30 (12) ◽  
pp. 2993-3002 ◽  
Author(s):  
Ngoc Van Tran Thi ◽  
Hee Sook Hwang ◽  
Yugyeong Kim ◽  
Han Chang Kang ◽  
Kang Moo Huh
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Physicochemical Characterization ◽  
Poly Ethylene Glycol ◽  
Triggered Drug Release ◽  
Self Assembled ◽  
Poly Ethylene

Intracellular thiol-responsive nanosized drug carriers self-assembled by poly(ethylene glycol)-b-poly(ε-caprolactone)-b-poly(ethylene glycol) having multiple bioreducible disulfide linkages in hydrophobic blocks

RSC Advances ◽  
2016 ◽  
Vol 6 (19) ◽  
pp. 15558-15576 ◽  
Author(s):  
Seung Yeon Moon ◽  
Yeon Su Choi ◽  
Jung-Kyo Cho ◽  
Minjong Yu ◽  
Eunji Lee ◽  
...  
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Polymeric Nanoparticles ◽  
Drug Carriers ◽  
Effective Drug ◽  
Poly Ethylene Glycol ◽  
Hydrophobic Domain ◽  
Disulfide Linkages ◽  
Self Assembled ◽  
Poly Ethylene

Intracellular thiol can trigger effective drug release from polymeric nanoparticles having multiple disulfide linkages in the hydrophobic domain.

Reversibly cross-linked poly(ethylene glycol)–poly(amino acid)s copolymer micelles: a promising approach to overcome the extracellular stability versus intracellular drug release challenge

RSC Advances ◽  
2015 ◽  
Vol 5 (26) ◽  
pp. 20025-20034 ◽  
Author(s):  
Yuling Li ◽  
Sai Wang ◽  
Dandan Zhu ◽  
Yuling Shen ◽  
Baixiang Du ◽  
...  
Keyword(s):  
Amino Acid ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Lipoic Acid ◽  
Triblock Copolymer ◽  
Intracellular Delivery ◽  
Poly Ethylene Glycol ◽  
Copolymer Micelles ◽  
Poly Ethylene ◽  
Copolymer Poly

Reversibly shell cross-linked micelles based on a lipoic acid (LA) decorated triblock copolymer poly(ethylene glycol)-b-poly(γ-benzyl-l-glutamate)-b-poly(l-phenylalanine) have been developed for efficient intracellular delivery of DOX.

Controlled Release Behaviors of Ketoprofen from Matrix Polymer of Chitosan and poly(ethylene glycol)

2013 ◽  
Vol 813 ◽  
pp. 399-402
Author(s):  
Chimsook Thitipha ◽  
Thitiphan Chimsook
Keyword(s):  
Particle Size ◽  
Controlled Release ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Diffusion Method ◽  
Poly Ethylene Glycol ◽  
Matrix Polymer ◽  
Percentage Yield ◽  
Poly Ethylene ◽  
Composition Ratios

The aim of present work was to prepare floating microsphere of ketoprofen using matrix polymer of chitosan and poly (ethylene glycol) by solvent diffusion method. The floating microsphere of ketoprofen was prepared from matrix polymer of chitosan and poly (ethylene glycol) with various composition ratios and evaluated such as particle size, drug compatibility and drug release of microspheres. The scanning electron microscopy of microspheres confirmed their hollow structures with smooth surface. Formulation CPK 4 to CPK 6 exhibited the best controlled release pattern in ketoprofen. The concentration and size of poly (ethylene-glycol) affected the particle size, percentage yield and drug release of microspheres.

scholarly journals Hydrolysis and drug release from poly(ethylene glycol)-modified lactone polymers with open porosity

2019 ◽  
Vol 113 ◽  
pp. 165-175 ◽  
Author(s):  
Sanja Asikainen ◽  
Kaarlo Paakinaho ◽  
Anna-Kaisa Kyhkynen ◽  
Markus Hannula ◽  
Minna Malin ◽  
...  
Keyword(s):  
Drug Release ◽  
Ethylene Glycol ◽  
Open Porosity ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Star-shaped poly(l-lactide)-b-poly(ethylene glycol) with porphyrin core: synthesis, self-assembly, drug-release behavior and singlet oxygen research

2014 ◽  
Vol 38 (8) ◽  
pp. 3569-3578 ◽  
Author(s):  
Xiao-Hui Dai ◽  
Zhi-Ming Wang ◽  
Lu-You Gao ◽  
Jian-Ming Pan ◽  
Xiao-Hong Wang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Block Copolymer ◽  
Drug Release ◽  
Ethylene Glycol ◽  
Self Assembly ◽  
Release Behavior ◽  
Poly Ethylene Glycol ◽  
Drug Release Behavior ◽  
Porphyrin Core ◽  
Poly Ethylene

pH-induced block copolymer SPPLA-b-PEG with porphyrin core for photodynamic therapy.

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