Nano-cellulose 3D-networks as controlled-release drug carriers

2013 ◽  
Vol 1 (23) ◽  
pp. 2976 ◽  
Author(s):  
Lin Huang ◽  
Xiuli Chen ◽  
Thanh Xuan Nguyen ◽  
Huiru Tang ◽  
Liming Zhang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Carriers ◽  
Release Drug ◽  
Nano Cellulose ◽  
3D Networks

scholarly journals Preparation and Sustained-Release Performance of PLGA Microcapsule Carrier System

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1758
Author(s):  
Shuaikai Ren ◽  
Chunxin Wang ◽  
Liang Guo ◽  
Congcong Xu ◽  
Yan Wang ◽  
...  
Keyword(s):  
Controlled Release ◽  
Biomedical Applications ◽  
Encapsulation Efficiency ◽  
Drug Carriers ◽  
Optimum Conditions ◽  
Carrier System ◽  
Preparation Conditions ◽  
Encapsulation Rate ◽  
Release Drug ◽  
Release Curve

Microcapsules have been widely studied owing to their biocompatibility and potential for application in various areas, particularly drug delivery. However, the size of microcapsules is difficult to control, and the size distribution is very broad via various encapsulation techniques. Therefore, it is necessary to obtain microcapsules with uniform and tailored size for the construction of controlled-release drug carriers. In this study, emulsification and solvent evaporation methods were used to prepare a variety of ovalbumin-loaded poly (lactic-co-glycolic acid) (PLGA) microcapsules to determine the optimal preparation conditions. The particle size of the PLGA microcapsules prepared using the optimum conditions was approximately 200 nm, which showed good dispersibility with an ovalbumin encapsulation rate of more than 60%. In addition, porous microcapsules with different pore sizes were prepared by adding a varying amount of porogen bovine serum albumin (BSA) to the internal water phase. The release curve showed that the rate of protein release from the microcapsules could be controlled by adjusting the pore size. These findings demonstrated that we could tailor the morphology and structure of microcapsules by regulating the preparation conditions, thus controlling the encapsulation efficiency and the release performance of the microcapsule carrier system. We envision that this controlled-release novel microcapsule carrier system shows great potential for biomedical applications.

Controlled-release drug carriers based mesoporous silica spheres with hierarchical hollow/nano structure

2016 ◽  
Vol 24 (1) ◽  
pp. 241-248 ◽  
Author(s):  
Yifei Teng ◽  
Yanqiu Jiang ◽  
Yining Zhang ◽  
Xianzhu Xu ◽  
Kaifeng Lin
Keyword(s):  
Controlled Release ◽  
Mesoporous Silica ◽  
Drug Carriers ◽  
Silica Spheres ◽  
Nano Structure ◽  
Release Drug ◽  
Mesoporous Silica Spheres

Controlled-release drug carriers based hierarchical silica microtubes templated from cellulose acetate nanofibers

2015 ◽  
Vol 132 (38) ◽  
pp. n/a-n/a ◽  
Author(s):  
Chengying Jia ◽  
Junlong Song ◽  
Yongcan Jin ◽  
Orlando J. Rojas
Keyword(s):  
Controlled Release ◽  
Cellulose Acetate ◽  
Drug Carriers ◽  
Release Drug

scholarly journals Thermosensitive star polymer pompons with a core–arm structure as thermo-responsive controlled release drug carriers

RSC Advances ◽  
2018 ◽  
Vol 8 (28) ◽  
pp. 15604-15612 ◽  
Author(s):  
Na Xu ◽  
Xiaobei Huang ◽  
Guangfu Yin ◽  
Meijiao Bu ◽  
Ximing Pu ◽  
...  
Keyword(s):  
Controlled Release ◽  
Drug Carrier ◽  
Drug Carriers ◽  
Star Polymer ◽  
Release Drug

Herein, a thermosensitive star polymer pompon with a core–arm structure was synthesized using a grafting-on method as a thermo-responsive controlled release drug carrier.

scholarly journals Carrier-Free Microspheres of an Anti-Cancer Drug Synthesized via a Sodium Catalyst for Controlled-Release Drug Delivery

Materials ◽  
2018 ◽  
Vol 11 (2) ◽  
pp. 281 ◽  
Author(s):  
Yong Xie ◽  
Xinxin Ma ◽  
Xujie Liu ◽  
Qingming Long ◽  
Yu Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Cancer Drug ◽  
Release Drug ◽  
Anti Cancer ◽  
Carrier Free
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