Effect of virgin coconut oil enriched diet on the antioxidant status and paraoxonase 1 activity in ameliorating the oxidative stress in rats – a comparative study

2013 ◽  
Vol 4 (9) ◽  
pp. 1402 ◽  
Author(s):  
S. Arunima ◽  
T. Rajamohan
Keyword(s):  
Oxidative Stress ◽  
Comparative Study ◽  
Antioxidant Status ◽  
Coconut Oil ◽  
Paraoxonase 1 ◽  
Virgin Coconut Oil

scholarly journals A Comparative Study of the Physicochemical Properties of a Virgin Coconut Oil Emulsion and Commercial Food Supplement Emulsions

Molecules ◽  
2014 ◽  
Vol 19 (7) ◽  
pp. 9187-9202 ◽  
Author(s):  
Yih Khor ◽  
Soo Koh ◽  
Kamariah Long ◽  
Shariah Long ◽  
Sharifah Ahmad ◽  
...  
Keyword(s):  
Comparative Study ◽  
Physicochemical Properties ◽  
Coconut Oil ◽  
Food Supplement ◽  
Virgin Coconut Oil ◽  
Oil Emulsion

scholarly journals Enhanced memory in Wistar rats by virgin coconut oil is associated with increased antioxidative, cholinergic activities and reduced oxidative stress

2017 ◽  
Vol 55 (1) ◽  
pp. 825-832 ◽  
Author(s):  
Nur Syafiqah Rahim ◽  
Siong Meng Lim ◽  
Vasudevan Mani ◽  
Abu Bakar Abdul Majeed ◽  
Kalavathy Ramasamy
Keyword(s):  
Oxidative Stress ◽  
Wistar Rats ◽  
Coconut Oil ◽  
Virgin Coconut Oil

scholarly journals The protective role of virgin coconut oil on the alloxan-induced oxidative stress in the liver, kidneys and heart of diabetic rats

2019 ◽  
Vol 10 (4) ◽  
pp. 2114-2124 ◽  
Author(s):  
Siniša Đurašević ◽  
Nebojša Jasnić ◽  
Marko Prokić ◽  
Ilijana Grigorov ◽  
Vesna Martinović ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Coconut Oil ◽  
Protective Role ◽  
Diabetic Rats ◽  
Toxic Effects ◽  
Virgin Coconut Oil ◽  
Tissue Specific

Our results show that VCO supplementation ameliorates some toxic effects of alloxan induced diabetes, and that the changes are tissue specific.

scholarly journals Virgin Coconut Oil Ameliorates Colchicine Induced Cognitive Dysfunction- A Preclinical Study

2020 ◽  
Vol 26 (1) ◽  
pp. 1-12
Author(s):  
Jeena John ◽  
Naveen Kumar Sapa ◽  
Rekha R Shenoy
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Frontal Cortex ◽  
Cognitive Dysfunction ◽  
Unsaturated Fatty Acids ◽  
Ketone Bodies ◽  
Coconut Oil ◽  
Treated Group ◽  
Virgin Coconut Oil ◽  
Neuroprotective Effects

Background : Virgin coconut oil (VCO) has been identified as a potential cognitive strengthener associated with Alzheimer’s disease (AD). It contains medium chain fatty acids (MCFA) which are absorbed and easily metabolized by the liver to form ketone bodies. Ketone bodies are converted to acetyl Co-A in the brain which then enters the citric acid cycle to provide ATP and also serves as precursors of acetylcholine in neurons. Sunflower oil (SO) contains poly unsaturated fatty acids which has both anti-inflammatory and neuroprotective actions. To compare the neuroprotective effects of VCO and SO on biochemical parameters involved in the cognitive dysfunction induced by colchicine through intracerebroventricular (i.c.v) route.To assess the role of polyphenols and MCFA present in VCO in preventing oxidative stress and its influence on in neuroprotection and memory enhancement. Methods: In the present study, we induced dementia through i.c.v injection of colchicine after giving the diet enriched VCO and SO in rats for 60 days. Rats were sacrificed on the 22nd day after the administration of colchicine. Behavioral parameters were assessed during the study period and biochemical estimations were performed using frontal cortex and hippocampus isolated from rat brain. Results: From the memory and learning tests by Morris water maze, VCO treated group performed better than SO treated rats. VCO reversed the antagonistic effects induced by colchicine by decreasing the acetylcholinesterase and malondialdehyde levels and increasing the levels of catalase and superoxide dismutase. SO only reduced malondialdehyde levels in cortex and hippocampus. Conclusion: The results demonstrated potential beneficiary effects of VCO in the cognitive dysfunction induced by colchicine by enhancing acetylcholine levels in the frontal cortex and hippocampus and also by reducing oxidative stress induced by physiological oxidants.

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