scholarly journals Extracellular matrix and α5β1 integrin signaling control the maintenance of bone formation capacity by human adipose-derived stromal cells

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Nunzia Di Maggio ◽  
Elisa Martella ◽  
Agne Frismantiene ◽  
Therese J. Resink ◽  
Simone Schreiner ◽  
...  
2008 ◽  
Vol 14 (8) ◽  
pp. 1285-1294 ◽  
Author(s):  
Oju Jeon ◽  
Jong Won Rhie ◽  
Il-Kuen Kwon ◽  
Jae-Hwan Kim ◽  
Byung-Soo Kim ◽  
...  

Stem Cells ◽  
2011 ◽  
Vol 29 (8) ◽  
pp. 1241-1255 ◽  
Author(s):  
Benjamin Levi ◽  
Emily R. Nelson ◽  
Shuli Li ◽  
Aaron W. James ◽  
Jeong S. Hyun ◽  
...  

2018 ◽  
Vol 8 (5) ◽  
pp. 624-631
Author(s):  
Xiaoyu Li ◽  
Jinfeng Yao ◽  
Xinya Du ◽  
Wei Jing ◽  
Weidong Tian

Membranes ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 606
Author(s):  
Dilcele Silva Moreira Dziedzic ◽  
Bassam Felipe Mogharbel ◽  
Ana Carolina Irioda ◽  
Priscila Elias Ferreira Stricker ◽  
Maiara Carolina Perussolo ◽  
...  

Periodontitis is a prevalent disease characterized by the loss of periodontal supporting tissues, bone, periodontal ligament, and cementum. The application of a bone tissue engineering strategy with Decellularized Human Amniotic Membrane (DAM) with adipose-derived stromal cells (ASCs) has shown to be convenient and valuable. This study aims to investigate the treatments of a rat periodontal furcation defect model with DAM, ASCs, and a mineralized extracellular matrix (ECM). Rat ASCs were expanded, cultivated on DAM, and with a bone differentiation medium for four weeks, deposited ECM on DAM. Periodontal healing for four weeks was evaluated by micro-computed tomography and histological analysis after treatments with DAM, ASCs, and ECM and compared to untreated defects on five consecutive horizontal levels, from gingival to apical. The results demonstrate that DAM preserves its structure during cultivation and healing periods, supporting cell attachment, permeation, bone deposition on DAM, and periodontal regeneration. DAM and DAM+ASCs enhance bone healing compared to the control on the gingival level. In conclusion, DAM with ASC or without cells and the ECM ensures bone tissue healing. The membrane supported neovascularization and promoted osteoconduction.


2010 ◽  
Vol 34 (1) ◽  
pp. 46-54 ◽  
Author(s):  
Xiaoyu Li ◽  
Jinfeng Yao ◽  
Ling Wu ◽  
Wei Jing ◽  
Wei Tang ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
pp. 20-26
Author(s):  
Shaowen Cheng ◽  
Jingkai Zhao ◽  
Xu Zhang ◽  
Hua Zhang ◽  
Lei Peng ◽  
...  

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