scholarly journals Noninvasive Imaging of Lipid Nanoparticle–Mediated Systemic Delivery of Small-Interfering RNA to the Liver

2010 ◽  
Vol 18 (9) ◽  
pp. 1657-1666 ◽  
Author(s):  
Weikang Tao ◽  
Joseph P Davide ◽  
Mingmei Cai ◽  
Guo-Jun Zhang ◽  
Victoria J South ◽  
...  
Keyword(s):  
Small Interfering Rna ◽  
Noninvasive Imaging ◽  
Systemic Delivery ◽  
Lipid Nanoparticle ◽  
Interfering Rna

scholarly journals Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

2011 ◽  
Vol 59 (8) ◽  
pp. 727-740 ◽  
Author(s):  
Bin Shi ◽  
Ed Keough ◽  
Andrea Matter ◽  
Karen Leander ◽  
Stephanie Young ◽  
...  
Keyword(s):  
Small Interfering Rna ◽  
Lipid Nanoparticle ◽  
Interfering Rna

scholarly journals Nanomedical Devices and Cancer Theranostics

2020 ◽  
Vol 6 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Mohamed Moumaris ◽  
Jean-Michel Bretagne ◽  
Nisen Abuaf
Keyword(s):  
Quantum Dot ◽  
Small Interfering Rna ◽  
Target Genes ◽  
Malignant Tumors ◽  
Whole Body ◽  
Systemic Delivery ◽  
Non Invasive ◽  
Current Therapies ◽  
Cancer Theranostics ◽  
Interfering Rna

The current therapies against cancer showed limited success. Nanotechnology is a promising strategy for cancer tracking, diagnosis, and therapy. The hybrid nanotechnology assembled several materials in a multimodal system to develop multifunctional approaches to cancer treatment. The quantum dot and polymer are some of these hybrid nanoparticle platforms. The quantum dot hybrid system possesses photonic and magnetic properties, allowing photothermal therapy and live multimodal imaging of cancer. These quantum dots were used to convey medicines to cancer cells. Hybrid polymer nanoparticles were utilized for the systemic delivery of small interfering RNA to malignant tumors and metastasis. They allowed non-invasive imaging to track in real-time the biodistribution of small interfering RNA in the whole body. They offer an opportunity to treat cancers by specifically silencing target genes. This review highlights the major nanotechnology approaches to effectively treat cancer and metastasis.

scholarly journals Lipid Nanoparticle-mediated Delivery of Small Interfering RNA for Cancer Therapy

Oleoscience ◽  
2016 ◽  
Vol 16 (6) ◽  
pp. 271-278
Author(s):  
Tomohiro ASAI ◽  
Takehisa DEWA ◽  
Naoto OKU
Keyword(s):  
Cancer Therapy ◽  
Small Interfering Rna ◽  
Lipid Nanoparticle ◽  
Interfering Rna
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